1HJ6

ISOCITRATE DEHYDROGENASE S113E MUTANT COMPLEXED WITH ISOPROPYLMALATE, NADP+ AND MAGNESIUM (FLASH-COOLED)

Summary for 1HJ6

Entry DOI	10.2210/pdb1hj6/pdb
Related	1AI2 1AI3 1BL5 1CW1 1CW4 1CW7 1GRO 1GRP 1IDC 1IDD 1IDE 1IDF 1ISO 1SJS
Descriptor	ISOCITRATE DEHYDROGENASE, GLYCEROL, 3-ISOPROPYLMALIC ACID, ... (6 entities in total)
Functional Keywords	oxidoreductase, oxidoreductase (nad(a)-choh(d)), nadp, phosphorylation, glyoxylate bypass
Biological source	ESCHERICHIA COLI
Total number of polymer chains	1
Total formula weight	46979.67
Authors	Doyle, S.A.,Beernink, P.T.,Koshland Junior, D.E. (deposition date: 2001-01-08, release date: 2001-01-16, Last modification date: 2011-07-13)
Primary citation	Doyle, S.A.,Beernink, P.T.,Koshland Junior, D.E. Structural Basis for a Change in Substrate Specificity: Crystal Structure of S113E Isocitrate Dehydrogenase in a Complex with Isopropylmalate, Mg2+ and Nadp Biochemistry, 40:4234-, 2001 Cited by PubMed: 11284679 DOI: 10.1021/BI002533Q PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation