1ISO
ISOCITRATE DEHYDROGENASE: STRUCTURE OF AN ENGINEERED NADP+--> NAD+ SPECIFICITY-REVERSAL MUTANT
Summary for 1ISO
Entry DOI | 10.2210/pdb1iso/pdb |
Descriptor | ISOCITRATE DEHYDROGENASE, SULFATE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (4 entities in total) |
Functional Keywords | nadp, phosphorylation, glyoxylate bypass, oxidoreductase |
Biological source | Escherichia coli |
Total number of polymer chains | 1 |
Total formula weight | 46652.99 |
Authors | Hurley, J.H. (deposition date: 1996-03-01, release date: 1996-12-07, Last modification date: 2024-05-22) |
Primary citation | Hurley, J.H.,Chen, R.,Dean, A.M. Determinants of cofactor specificity in isocitrate dehydrogenase: structure of an engineered NADP+ --> NAD+ specificity-reversal mutant. Biochemistry, 35:5670-5678, 1996 Cited by PubMed: 8639526DOI: 10.1021/bi953001q PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
Download full validation report