4AJC

3D structure of E. coli Isocitrate Dehydrogenase K100M mutant in complex with alpha-ketoglutarate, calcium(II) and adenine nucleotide phosphate

Summary for 4AJC

Entry DOI	10.2210/pdb4ajc/pdb
Related	4AJ3 4AJA 4AJB
Descriptor	NADP ISOCITRATE DEHYDROGENASE, ADENOSINE-2'-5'-DIPHOSPHATE, 2-OXOGLUTARIC ACID, ... (6 entities in total)
Functional Keywords	oxidoreductase, oxidative beta-decarboxylation
Biological source	ESCHERICHIA COLI
Total number of polymer chains	1
Total formula weight	46521.02
Authors	Goncalves, S.,Miller, S.P.,Carrondo, M.A.,Dean, A.M.,Matias, P.M. (deposition date: 2012-02-16, release date: 2012-10-31, Last modification date: 2023-12-20)
Primary citation	Goncalves, S.,Miller, S.P.,Carrondo, M.A.,Dean, A.M.,Matias, P.M. Induced Fit and the Catalytic Mechanism of Isocitrate Dehydrogenase. Biochemistry, 51:7098-, 2012 Cited by PubMed: 22891681 DOI: 10.1021/BI300483W PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation