4AJ3
3D structure of E. coli Isocitrate Dehydrogenase in complex with Isocitrate, calcium(II) and NADP - The pseudo-Michaelis complex
Summary for 4AJ3
| Entry DOI | 10.2210/pdb4aj3/pdb |
| Related | 4AJA 4AJB 4AJC 4AJR 4AJS |
| Descriptor | NADP ISOCITRATE DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ISOCITRIC ACID, ... (5 entities in total) |
| Functional Keywords | oxidoreductase, oxidative beta-decarboxylation |
| Biological source | ESCHERICHIA COLI |
| Total number of polymer chains | 1 |
| Total formula weight | 46785.17 |
| Authors | Goncalves, S.,Miller, S.P.,Carrondo, M.A.,Dean, A.M.,Matias, P.M. (deposition date: 2012-02-15, release date: 2012-10-31, Last modification date: 2023-12-20) |
| Primary citation | Goncalves, S.,Miller, S.P.,Carrondo, M.A.,Dean, A.M.,Matias, P.M. Induced Fit and the Catalytic Mechanism of Isocitrate Dehydrogenase. Biochemistry, 51:7098-, 2012 Cited by PubMed: 22891681DOI: 10.1021/BI300483W PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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