4AJS

3D structure of E. coli Isocitrate Dehydrogenase K100M mutant in complex with isocitrate, magnesium(II), Adenosine 2',5'-biphosphate and ribosylnicotinamide-5'-phosphate

Summary for 4AJS

Entry DOI	10.2210/pdb4ajs/pdb
Related	1AI2 1AI3 1BL5 1CW1 1CW4 1CW7 1GRO 1GRP 1HJ6 1IDC 1IDD 1IDE 1IDF 1IKA 1ISO 1P8F 1PB1 1PB3 1SJS 3ICD 4AJR 4ICD 5ICD 6ICD 7ICD 8ICD 9ICD
Descriptor	ISOCITRATE DEHYDROGENASE [NADP], ADENOSINE-2'-5'-DIPHOSPHATE, ISOCITRIC ACID, ... (7 entities in total)
Functional Keywords	oxidoreductase, oxidative beta-decarboxylation
Biological source	ESCHERICHIA COLI
Total number of polymer chains	1
Total formula weight	46886.50
Authors	Goncalves, S.,Miller, S.P.,Carrondo, M.A.,Dean, A.M.,Matias, P.M. (deposition date: 2012-02-17, release date: 2012-10-31, Last modification date: 2023-12-20)
Primary citation	Goncalves, S.,Miller, S.P.,Carrondo, M.A.,Dean, A.M.,Matias, P.M. Induced Fit and the Catalytic Mechanism of Isocitrate Dehydrogenase. Biochemistry, 51:7098-, 2012 Cited by PubMed: 22891681 DOI: 10.1021/BI300483W PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.802 Å)

Structure validation