4AJS
3D structure of E. coli Isocitrate Dehydrogenase K100M mutant in complex with isocitrate, magnesium(II), Adenosine 2',5'-biphosphate and ribosylnicotinamide-5'-phosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ISOCITRATE DEHYDROGENASE [NADP] | polymer | 416 | 45811.6 | 1 | UniProt (P08200) Pfam (PF00180) | ESCHERICHIA COLI | IDH, IDP, NADP(+)-SPECIFIC ICDH, OXALOSUCCINATE DECARBOXYLASE, ISOCITRATE DEHYDROGENASE |
| 2 | B (A) | ADENOSINE-2'-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (A2P) | |||
| 3 | C (A) | ISOCITRIC ACID | non-polymer | 192.1 | 1 | Chemie (ICT) | |||
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | E (A) | BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE | non-polymer | 335.2 | 1 | Chemie (NMN) | |||
| 6 | F (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 7 | G (A) | water | water | 18.0 | 504 | Chemie (HOH) |
Sequence modifications
A: 1 - 416 (UniProt: P08200)
| PDB | External Database | Details |
|---|---|---|
| Met 100 | Lys 100 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 45811.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1074.9 | |
| All* | Total formula weight | 46886.5 |
