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PDB: 45 件
4Z4F
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BU of 4z4f by Molmil
Human Argonaute2 Bound to t1-DAP Target RNA
分子名称: MAGNESIUM ION, PHENOL, Protein argonaute-2, ...
著者Schirle, N.T, MacRae, I.J.
登録日2015-04-02
公開日2015-09-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015
4Z4D
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BU of 4z4d by Molmil
Human Argonaute2 Bound to t1-G Target RNA
分子名称: ISOPROPYL ALCOHOL, MAGNESIUM ION, PHENOL, ...
著者Schirle, N.T, MacRae, I.J.
登録日2015-04-02
公開日2015-09-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015
4Z4C
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BU of 4z4c by Molmil
Human Argonaute2 Bound to t1-C Target RNA
分子名称: ISOPROPYL ALCOHOL, MAGNESIUM ION, PHENOL, ...
著者Schirle, N.T, MacRae, I.J.
登録日2015-04-02
公開日2015-09-23
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.303 Å)
主引用文献Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015
7KX9
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BU of 7kx9 by Molmil
Cryo-EM structure of Ephydatia fluviatilis PiwiA-piRNA-target complex
分子名称: MAGNESIUM ION, Piwi-A, RNA (5'-R(P*UP*CP*UP*CP*UP*UP*GP*AP*GP*UP*UP*GP*GP*AP*CP*AP*AP*AP*UP*GP*GP*CP*AP*(OMG))-3'), ...
著者Anzelon, T.A, Chowdhury, S, Lander, G.C, MacRae, I.J.
登録日2020-12-03
公開日2021-07-14
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis for piRNA targeting.
Nature, 597, 2021
7KX7
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BU of 7kx7 by Molmil
Cryo-EM structure of Ephydatia fluviatilis PiwiA-piRNA complex
分子名称: MAGNESIUM ION, Piwi-A, RNA (5'-R(P*UP*CP*UP*CP*AP*GP*(OMC))-3')
著者Anzelon, T.A, Chowdhury, S, Lander, G.C, MacRae, I.J.
登録日2020-12-03
公開日2021-07-14
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis for piRNA targeting.
Nature, 597, 2021
7KI3
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BU of 7ki3 by Molmil
Human Argonaute2:miR-122 bound to the HCV genotype 1a site-1 RNA
分子名称: BARIUM ION, HCV genotype 1a miR-122 site-1, Protein argonaute-2, ...
著者Gebert, L.F.R, MacRae, I.J.
登録日2020-10-22
公開日2021-10-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A structured RNA motif locks Argonaute2:miR-122 onto the 5' end of the HCV genome.
Nat Commun, 12, 2021
4Z4H
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BU of 4z4h by Molmil
Human Argonaute2 A481T Mutant Bound to t1-A Target RNA
分子名称: MAGNESIUM ION, PHENOL, Protein argonaute-2, ...
著者Schirle, N.T, MacRae, I.J.
登録日2015-04-02
公開日2015-09-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.504 Å)
主引用文献Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015
4Z4I
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BU of 4z4i by Molmil
Human Argonaute2 A481T Mutant Bound to t1-G Target RNA
分子名称: MAGNESIUM ION, PHENOL, Protein argonaute-2, ...
著者Schirle, N.T, MacRae, I.J.
登録日2015-04-02
公開日2015-09-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.801 Å)
主引用文献Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015
4Z4E
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BU of 4z4e by Molmil
Human Argonaute2 Bound to t1-U Target RNA
分子名称: ISOPROPYL ALCOHOL, MAGNESIUM ION, PHENOL, ...
著者Schirle, N.T, MacRae, I.J.
登録日2015-04-02
公開日2015-09-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015
4Z4G
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BU of 4z4g by Molmil
Human Argonaute2 Bound to t1-Inosine Target RNA
分子名称: MAGNESIUM ION, PHENOL, Protein argonaute-2, ...
著者Schirle, N.T, MacRae, I.J.
登録日2015-04-02
公開日2015-09-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.
Elife, 4, 2015
6BJG
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BU of 6bjg by Molmil
CIRV p19 mutant T111H in complex with siRNA
分子名称: RNA (5'-R(P*CP*GP*UP*AP*CP*GP*CP*GP*GP*AP*AP*UP*AP*CP*UP*UP*CP*GP*AP*UP*U)-3'), RNA (5'-R(P*UP*CP*GP*AP*AP*GP*UP*AP*UP*UP*CP*CP*GP*CP*GP*UP*AP*CP*GP*UP*U)-3'), RNA silencing suppressor p19
著者Foss, D.V, Schirle, N, Pezacki, J.P, Macrae, I.J.
登録日2017-11-06
公開日2019-01-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Structural insights into interactions between viral suppressor of RNA silencing protein p19 mutants and small RNAs.
Febs Open Bio, 9, 2019
6BJH
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BU of 6bjh by Molmil
CIRV p19 mutant T111S in complex with siRNA
分子名称: RNA (5'-R(P*CP*GP*UP*AP*CP*GP*CP*GP*GP*AP*AP*UP*AP*CP*UP*UP*CP*GP*AP*UP*U)-3'), RNA (5'-R(P*UP*CP*GP*AP*AP*GP*UP*AP*UP*UP*CP*CP*GP*CP*GP*UP*AP*CP*GP*UP*U)-3'), RNA silencing suppressor p19
著者Foss, D.V, Schirle, N.T, MacRae, I.J, Pezacki, J.P.
登録日2017-11-06
公開日2019-01-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Structural insights into interactions between viral suppressor of RNA silencing protein p19 mutants and small RNAs.
Febs Open Bio, 9, 2019
6BJV
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BU of 6bjv by Molmil
CIRV p19 protein in complex with siRNA
分子名称: RNA (5'-R(P*CP*GP*UP*AP*CP*GP*CP*GP*GP*AP*AP*UP*AP*CP*UP*UP*CP*GP*AP*UP*U)-3'), RNA (5'-R(P*UP*CP*GP*AP*AP*GP*UP*AP*UP*UP*CP*CP*GP*CP*GP*UP*AP*CP*GP*UP*U)-3'), RNA silencing suppressor p19
著者Foss, D.V, Schirle, N, Pezacki, J.P, Macrae, I.J.
登録日2017-11-07
公開日2019-01-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.198 Å)
主引用文献Structural insights into interactions between viral suppressor of RNA silencing protein p19 mutants and small RNAs.
Febs Open Bio, 9, 2019
6CBD
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BU of 6cbd by Molmil
Crystal Structure of Human Argonaute2 Bound to Three Tryptophans
分子名称: Guide RNA, ISOPROPYL ALCOHOL, MAGNESIUM ION, ...
著者Sheu-Gruttadauria, J, MacRae, I.J.
登録日2018-02-02
公開日2018-04-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.203 Å)
主引用文献Phase Transitions in the Assembly and Function of Human miRISC.
Cell, 173, 2018
6MFR
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BU of 6mfr by Molmil
Human Argonaute2-miR-122 bound to a target RNA with three central mismatches (bu3)
分子名称: PHENOL, PHOSPHATE ION, Protein argonaute-2, ...
著者Sheu-Gruttadauria, J, MacRae, I.J.
登録日2018-09-12
公開日2019-08-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structural Basis for Target-Directed MicroRNA Degradation.
Mol.Cell, 75, 2019
6MFN
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BU of 6mfn by Molmil
Human Argonaute2-miR-27a bound to HSUR1 target RNA
分子名称: PHENOL, Protein argonaute-2, RNA (5'-R(P*UP*CP*UP*GP*UP*GP*AP*UP*AP*A)-3'), ...
著者Sheu-Gruttadauria, J, MacRae, I.J.
登録日2018-09-11
公開日2019-08-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis for Target-Directed MicroRNA Degradation.
Mol.Cell, 75, 2019
6NIT
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BU of 6nit by Molmil
Human Argonaute2-miR-122 bound to a target RNA with four central mismatches (bu4)
分子名称: Protein argonaute-2, RNA (5'-R(P*AP*AP*CP*AP*CP*CP*AP*UP*CP*CP*AP*AP*CP*AP*CP*UP*CP*CP*AP*AP*A)-3'), RNA (5'-R(P*UP*GP*GP*AP*GP*UP*GP*UP*GP*AP*CP*AP*AP*UP*GP*GP*UP*GP*UP*UP*U)-3')
著者Sheu-Gruttadauria, J, MacRae, I.J.
登録日2018-12-31
公開日2019-08-07
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural Basis for Target-Directed MicroRNA Degradation.
Mol.Cell, 75, 2019
6N4O
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BU of 6n4o by Molmil
Human Argonaute2-miR-122 bound to a seed and supplementary paired target
分子名称: Protein argonaute-2, RNA (5'-R(*CP*CP*AP*UP*UP*GP*UP*CP*AP*CP*AP*CP*UP*CP*CP*AP*AP*A)-3'), RNA (5'-R(P*UP*GP*GP*AP*GP*UP*GP*UP*GP*AP*CP*AP*AP*UP*GP*GP*UP*GP*UP*UP*U)-3')
著者Sheu-Gruttadauria, J, MacRae, I.J.
登録日2018-11-19
公開日2019-05-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.899 Å)
主引用文献Beyond the seed: structural basis for supplementary microRNA targeting by human Argonaute2.
Embo J., 38, 2019
6MDZ
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BU of 6mdz by Molmil
Human Argonaute2-miR-122 bound to a target RNA with two central mismatches (bu2)
分子名称: PHENOL, Protein argonaute-2, RNA (5'-R(P*AP*AP*AP*CP*AP*CP*CP*AP*UP*UP*UP*CP*CP*AP*CP*AP*CP*UP*CP*CP*AP*AP*A)-3'), ...
著者Sheu-Gruttadauria, J, MacRae, I.J.
登録日2018-09-05
公開日2019-08-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural Basis for Target-Directed MicroRNA Degradation.
Mol.Cell, 75, 2019
2FFL
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BU of 2ffl by Molmil
Crystal Structure of Dicer from Giardia intestinalis
分子名称: Dicer, MANGANESE (II) ION
著者Doudna, J.A, MacRae, I.J, Adams, P.D.
登録日2005-12-19
公開日2006-01-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.33 Å)
主引用文献Structural Basis of Double-Stranded RNA Processing by Dicer
Science, 311, 2006
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