7KI3
Human Argonaute2:miR-122 bound to the HCV genotype 1a site-1 RNA
Summary for 7KI3
| Entry DOI | 10.2210/pdb7ki3/pdb |
| Descriptor | Protein argonaute-2, miR-122, HCV genotype 1a miR-122 site-1, ... (4 entities in total) |
| Functional Keywords | argonaute, mir-122, hcv, complex, hydrolase-rna complex, hydrolase/rna |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 6 |
| Total formula weight | 228672.37 |
| Authors | Gebert, L.F.R.,MacRae, I.J. (deposition date: 2020-10-22, release date: 2021-10-06, Last modification date: 2023-10-18) |
| Primary citation | Gebert, L.F.R.,Law, M.,MacRae, I.J. A structured RNA motif locks Argonaute2:miR-122 onto the 5' end of the HCV genome. Nat Commun, 12:6836-6836, 2021 Cited by PubMed: 34824224DOI: 10.1038/s41467-021-27177-9 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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