6BJH

CIRV p19 mutant T111S in complex with siRNA

Summary for 6BJH

• Entry DOI: 10.2210/pdb6bjh/pdb
• Descriptor: RNA silencing suppressor p19, RNA (5'-R(P*UP*CP*GP*AP*AP*GP*UP*AP*UP*UP*CP*CP*GP*CP*GP*UP*AP*CP*GP*UP*U)-3'), RNA (5'-R(P*CP*GP*UP*AP*CP*GP*CP*GP*GP*AP*AP*UP*AP*CP*UP*UP*CP*GP*AP*UP*U)-3'), ... (4 entities in total)
• Functional Keywords: viral suppressor, rna silencing sirna, high affinity for human mirna-122, rna binding protein
• Biological source: Carnation Italian ringspot virus (CIRV); More
• Total number of polymer chains: 4
• Total formula weight: 52045.66

Authors

Foss, D.V.,Schirle, N.T.,MacRae, I.J.,Pezacki, J.P. (deposition date: 2017-11-06, release date: 2019-01-16, Last modification date: 2023-10-04)

• Primary citation: Foss, D.V.,Schirle, N.T.,MacRae, I.J.,Pezacki, J.P.; Structural insights into interactions between viral suppressor of RNA silencing protein p19 mutants and small RNAs.; Febs Open Bio, 9:1042-1051, 2019; PubMed: 31021526; DOI: 10.1002/2211-5463.12644

Experimental method

X-RAY DIFFRACTION (2.58 Å)