1VDY
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![BU of 1vdy by Molmil](/molmil-images/mine/1vdy) | NMR Structure of the hypothetical ENTH-VHS domain At3g16270 from Arabidopsis thaliana | Descriptor: | hypothetical protein (RAFL09-17-B18) | Authors: | Lopez-Mendez, B, Pantoja-Uceda, D, Tomizawa, T, Koshiba, S, Kigawa, T, Shirouzu, M, Terada, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Seki, M, Shinozaki, K, Yokoyama, S, Guntert, P, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-03-25 | Release date: | 2005-05-03 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of the hypothetical ENTH-VHS domain AT3G16270 from arabidopsis thaliana To be Published
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3LIJ
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![BU of 3lij by Molmil](/molmil-images/mine/3lij) | Crystal structure of full length CpCDPK3 (cgd5_820) in complex with Ca2+ and AMPPNP | Descriptor: | CALCIUM ION, Calcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands, MAGNESIUM ION, ... | Authors: | Qiu, W, Hutchinson, A, Wernimont, A, Walker, J.R, Sullivan, H, Lin, Y.-H, Mackenzie, F, Kozieradzki, I, Cossar, D, Schapira, M, Senisterra, G, Vedadi, M, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Bochkarev, A, Hui, R, Amani, M, Structural Genomics Consortium (SGC) | Deposit date: | 2010-01-25 | Release date: | 2010-02-02 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of full length CpCDPK3 (cgd5_820) in complex with Ca2+ and AMPPNP To be Published
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4JLG
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![BU of 4jlg by Molmil](/molmil-images/mine/4jlg) | SETD7 in complex with inhibitor (R)-PFI-2 and S-adenosyl-methionine | Descriptor: | 8-fluoro-N-{(2R)-1-oxo-1-(pyrrolidin-1-yl)-3-[3-(trifluoromethyl)phenyl]propan-2-yl}-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide, Histone-lysine N-methyltransferase SETD7, S-ADENOSYLMETHIONINE, ... | Authors: | Dong, A, Wu, H, Zeng, H, El Bakkouri, M, Barsyte, D, Vedadi, M, Tatlock, J, Owen, D, Bunnage, M, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Structural Genomics Consortium (SGC) | Deposit date: | 2013-03-12 | Release date: | 2013-04-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.896 Å) | Cite: | (R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells. Proc.Natl.Acad.Sci.USA, 111, 2014
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4JW2
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![BU of 4jw2 by Molmil](/molmil-images/mine/4jw2) | Selection of specific protein binders for pre-defined targets from an optimized library of artificial helicoidal repeat proteins (alphaRep) | Descriptor: | 1,2-ETHANEDIOL, A3 artificial protein, bA3-2: binder of A3 protein | Authors: | Guellouz, A, Valerio-Lepiniec, M, Urvoas, A, Chevrel, A, Graille, M, Fourati-Kammoun, Z, Desmadril, M, van Tilbeurgh, H, Minard, P. | Deposit date: | 2013-03-27 | Release date: | 2013-09-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Selection of Specific Protein Binders for Pre-Defined Targets from an Optimized Library of Artificial Helicoidal Repeat Proteins (alphaRep). Plos One, 8, 2013
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1HNL
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![BU of 1hnl by Molmil](/molmil-images/mine/1hnl) | |
7D56
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![BU of 7d56 by Molmil](/molmil-images/mine/7d56) | |
7D5V
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![BU of 7d5v by Molmil](/molmil-images/mine/7d5v) | Structure of the C646A mutant of peptidylarginine deiminase type III (PAD3) | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Protein-arginine deiminase type-3 | Authors: | Akimoto, M, Mashimo, R, Unno, M. | Deposit date: | 2020-09-28 | Release date: | 2021-06-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.102 Å) | Cite: | Structures of human peptidylarginine deiminase type III provide insights into substrate recognition and inhibitor design. Arch.Biochem.Biophys., 708, 2021
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4ZQN
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![BU of 4zqn by Molmil](/molmil-images/mine/4zqn) | Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis in the complex with IMP and the inhibitor P41 | Descriptor: | 2-chloro-N,N-dimethyl-5-[({2-[3-(prop-1-en-2-yl)phenyl]propan-2-yl}carbamoyl)amino]benzamide, INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase | Authors: | Kim, Y, Makowska-Grzyska, M, Gu, M, Kavitha, M, Hedstrom, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2015-05-10 | Release date: | 2015-06-17 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mycobacterium tuberculosis IMPDH in Complexes with Substrates, Products and Antitubercular Compounds. Plos One, 10, 2015
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7DAN
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7D5R
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![BU of 7d5r by Molmil](/molmil-images/mine/7d5r) | Structure of the Ca2+-bound C646A mutant of peptidylarginine deiminase type III (PAD3) | Descriptor: | CALCIUM ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Mashimo, R, Akimoto, M, Unno, M. | Deposit date: | 2020-09-28 | Release date: | 2021-06-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.148 Å) | Cite: | Structures of human peptidylarginine deiminase type III provide insights into substrate recognition and inhibitor design. Arch.Biochem.Biophys., 708, 2021
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7D4Y
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5DVH
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![BU of 5dvh by Molmil](/molmil-images/mine/5dvh) | |
7D8N
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![BU of 7d8n by Molmil](/molmil-images/mine/7d8n) | Structure of the inactive form of wild-type peptidylarginine deiminase type III (PAD3) crystallized under the condition with high concentrations of Ca2+ | Descriptor: | CALCIUM ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Funabashi, K, Sawata, M, Unno, M. | Deposit date: | 2020-10-08 | Release date: | 2021-06-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.753 Å) | Cite: | Structures of human peptidylarginine deiminase type III provide insights into substrate recognition and inhibitor design. Arch.Biochem.Biophys., 708, 2021
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6EHA
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![BU of 6eha by Molmil](/molmil-images/mine/6eha) | Heme oxygenase 1 in complex with inhibitor | Descriptor: | 1-(3-imidazol-1-ylpropyl)-5-(2-methylpropyl)-4-phenyl-imidazole, Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Grudnik, P, Mieczkowski, M. | Deposit date: | 2017-09-12 | Release date: | 2018-10-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Development and characterization of a new inhibitor of heme oxygenase activity for cancer treatment. Arch.Biochem.Biophys., 671, 2019
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8B4T
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7DK0
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![BU of 7dk0 by Molmil](/molmil-images/mine/7dk0) | Crystal structure of SARS-CoV-2 Spike RBD in complex with MW05 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MW05 heavy chain, MW05 light chain, ... | Authors: | Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M. | Deposit date: | 2020-11-22 | Release date: | 2021-06-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.199 Å) | Cite: | Antibody-dependent enhancement (ADE) of SARS-CoV-2 pseudoviral infection requires Fc gamma RIIB and virus-antibody complex with bivalent interaction. Commun Biol, 5, 2022
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4J70
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![BU of 4j70 by Molmil](/molmil-images/mine/4j70) | Yeast 20S proteasome in complex with the belactosin derivative 3e | Descriptor: | Proteasome component C1, Proteasome component C11, Proteasome component C5, ... | Authors: | Kawamura, S, Unno, Y, List, A, Tanaka, M, Sasaki, T, Arisawa, M, Asai, A, Groll, M, Shuto, S. | Deposit date: | 2013-02-12 | Release date: | 2013-04-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Potent Proteasome Inhibitors Derived from the Unnatural cis-Cyclopropane Isomer of Belactosin A: Synthesis, Biological Activity, and Mode of Action. J.Med.Chem., 56, 2013
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7DJZ
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![BU of 7djz by Molmil](/molmil-images/mine/7djz) | Crystal structure of SARS-CoV-2 Spike RBD in complex with MW01 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, MW01 heavy chain, ... | Authors: | Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M. | Deposit date: | 2020-11-22 | Release date: | 2021-06-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.397 Å) | Cite: | Antibody-dependent enhancement (ADE) of SARS-CoV-2 pseudoviral infection requires Fc gamma RIIB and virus-antibody complex with bivalent interaction. Commun Biol, 5, 2022
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8B5F
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4JSB
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![BU of 4jsb by Molmil](/molmil-images/mine/4jsb) | Crystal structure of Tfu_1878, a putative enoyl-CoA hydratase from Thermobifida fusca YX | Descriptor: | Enoyl-CoA hydratase, SULFATE ION | Authors: | Mikolajczak, K, Porebski, P.J, Cooper, D.R, Ahmed, M, Stead, M, Hillerich, B, Seidel, R, Zimmerman, M, Bonanno, J.B, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2013-03-22 | Release date: | 2013-06-19 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Crystal structure of Tfu_1878, a putative enoyl-CoA hydratase from Thermobifida fusca YX TO BE PUBLISHED
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6RRA
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![BU of 6rra by Molmil](/molmil-images/mine/6rra) | X-RAY STRUCTURE OF THE FERREDOXIN-NADP REDUCTASE FROM BRUCELLA OVIS IN COMPLEX WITH NADP | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Ferredoxin--NADP reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Martinez-Julvez, M, Taleb, V, Medina, M. | Deposit date: | 2019-05-17 | Release date: | 2019-08-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Towards the competent conformation for catalysis in the ferredoxin-NADP+reductase from the Brucella ovis pathogen. Biochim Biophys Acta Bioenerg, 1860, 2019
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8S38
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![BU of 8s38 by Molmil](/molmil-images/mine/8s38) | Crystal structure of Medicago truncatula glutamate dehydrogenase 2 in complex with citrate and NAD | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, CITRIC ACID, ... | Authors: | Grzechowiak, M, Ruszkowski, M. | Deposit date: | 2024-02-19 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Legume-type glutamate dehydrogenase: Structure, activity, and inhibition studies. Int.J.Biol.Macromol., 278, 2024
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8S39
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![BU of 8s39 by Molmil](/molmil-images/mine/8s39) | Crystal structure of Medicago truncatula glutamate dehydrogenase 2 in complex with isophthalic acid and NAD | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Grzechowiak, M, Ruszkowski, M. | Deposit date: | 2024-02-19 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Legume-type glutamate dehydrogenase: Structure, activity, and inhibition studies. Int.J.Biol.Macromol., 278, 2024
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8S3A
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![BU of 8s3a by Molmil](/molmil-images/mine/8s3a) | Crystal structure of Medicago truncatula glutamate dehydrogenase 2 in complex with 2,6-pyridinedicarboxylic acid and NAD | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ... | Authors: | Grzechowiak, M, Ruszkowski, M. | Deposit date: | 2024-02-19 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Legume-type glutamate dehydrogenase: Structure, activity, and inhibition studies. Int.J.Biol.Macromol., 278, 2024
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8S3D
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![BU of 8s3d by Molmil](/molmil-images/mine/8s3d) | Crystal structure of Medicago truncatula glutamate dehydrogenase 2 in complex with 2-amino-2-hydroxyglutarate (reaction intermediate) and NAD | Descriptor: | (2S)-2-azanyl-2-oxidanyl-pentanedioic acid, 1,2-ETHANEDIOL, CALCIUM ION, ... | Authors: | Grzechowiak, M, Ruszkowski, M. | Deposit date: | 2024-02-19 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Legume-type glutamate dehydrogenase: Structure, activity, and inhibition studies. Int.J.Biol.Macromol., 278, 2024
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