7D5R
Structure of the Ca2+-bound C646A mutant of peptidylarginine deiminase type III (PAD3)
Summary for 7D5R
Entry DOI | 10.2210/pdb7d5r/pdb |
Related | 7D4Y 7D56 |
Descriptor | Protein-arginine deiminase type-3, CALCIUM ION, GLYCEROL, ... (4 entities in total) |
Functional Keywords | deimination, citrullination, peptidylarginine deiminase, post-translational modification, enzyme, isozyme, mutant, cytosolic protein, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 150320.86 |
Authors | Mashimo, R.,Akimoto, M.,Unno, M. (deposition date: 2020-09-28, release date: 2021-06-02, Last modification date: 2023-11-29) |
Primary citation | Funabashi, K.,Sawata, M.,Nagai, A.,Akimoto, M.,Mashimo, R.,Takahara, H.,Kizawa, K.,Thompson, P.R.,Ite, K.,Kitanishi, K.,Unno, M. Structures of human peptidylarginine deiminase type III provide insights into substrate recognition and inhibitor design. Arch.Biochem.Biophys., 708:108911-108911, 2021 Cited by PubMed: 33971157DOI: 10.1016/j.abb.2021.108911 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.148 Å) |
Structure validation
Download full validation report