7D56

Structure of the peptidylarginine deiminase type III (PAD3) in complex with Cl-amidine

Summary for 7D56

• Entry DOI: 10.2210/pdb7d56/pdb
• Related: 7D4Y
• Descriptor: Protein-arginine deiminase type-3, N-[(1S)-1-(AMINOCARBONYL)-4-(ETHANIMIDOYLAMINO)BUTYL]BENZAMIDE, CALCIUM ION, ... (7 entities in total)
• Functional Keywords: posttransrational modification, citrullination, calcium-dependent, calcium metabolism, cytosolic protein, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 3
• Total formula weight: 226621.21

Authors

Funabashi, K.,Unno, M. (deposition date: 2020-09-25, release date: 2021-06-02, Last modification date: 2023-11-29)

• Primary citation: Funabashi, K.,Sawata, M.,Nagai, A.,Akimoto, M.,Mashimo, R.,Takahara, H.,Kizawa, K.,Thompson, P.R.,Ite, K.,Kitanishi, K.,Unno, M.; Structures of human peptidylarginine deiminase type III provide insights into substrate recognition and inhibitor design.; Arch.Biochem.Biophys., 708:108911-108911, 2021; PubMed: 33971157; DOI: 10.1016/j.abb.2021.108911

Experimental method

X-RAY DIFFRACTION (3.175 Å)