7D8N

Structure of the inactive form of wild-type peptidylarginine deiminase type III (PAD3) crystallized under the condition with high concentrations of Ca2+

Summary for 7D8N

Entry DOI	10.2210/pdb7d8n/pdb
Related	7D4Y 7D56 7D5R 7D5V
Descriptor	Protein-arginine deiminase type-3, CALCIUM ION, GLYCEROL, ... (5 entities in total)
Functional Keywords	citrullination, inactive, isozyme, post-translational modification, calcium ion, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	150774.55
Authors	Funabashi, K.,Sawata, M.,Unno, M. (deposition date: 2020-10-08, release date: 2021-06-02, Last modification date: 2023-11-29)
Primary citation	Funabashi, K.,Sawata, M.,Nagai, A.,Akimoto, M.,Mashimo, R.,Takahara, H.,Kizawa, K.,Thompson, P.R.,Ite, K.,Kitanishi, K.,Unno, M. Structures of human peptidylarginine deiminase type III provide insights into substrate recognition and inhibitor design. Arch.Biochem.Biophys., 708:108911-108911, 2021 Cited by PubMed: 33971157 DOI: 10.1016/j.abb.2021.108911 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.753 Å)

Structure validation