7D5V

Structure of the C646A mutant of peptidylarginine deiminase type III (PAD3)

Summary for 7D5V

Entry DOI	10.2210/pdb7d5v/pdb
Related	7D4Y 7D56 7D5R
Descriptor	Protein-arginine deiminase type-3, 1,2-ETHANEDIOL, GLYCEROL, ... (4 entities in total)
Functional Keywords	peptidylarginine deiminase, isozyme, mutant, citrullination, post-translational modification, enzyme, cytosolic protein, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	151882.53
Authors	Akimoto, M.,Mashimo, R.,Unno, M. (deposition date: 2020-09-28, release date: 2021-06-02, Last modification date: 2023-11-29)
Primary citation	Funabashi, K.,Sawata, M.,Nagai, A.,Akimoto, M.,Mashimo, R.,Takahara, H.,Kizawa, K.,Thompson, P.R.,Ite, K.,Kitanishi, K.,Unno, M. Structures of human peptidylarginine deiminase type III provide insights into substrate recognition and inhibitor design. Arch.Biochem.Biophys., 708:108911-108911, 2021 Cited by PubMed: 33971157 DOI: 10.1016/j.abb.2021.108911 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.102 Å)

Structure validation