3BRJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3brj by Molmil](/molmil-images/mine/3brj) | Crystal structure of mannitol operon repressor (MtlR) from Vibrio parahaemolyticus RIMD 2210633 | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Mannitol operon repressor | Authors: | Tan, K, Zhou, M, Moy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2007-12-21 | Release date: | 2008-01-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | The mannitol operon repressor MtlR belongs to a new class of transcription regulators in bacteria. J.Biol.Chem., 284, 2009
|
|
4QLT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4qlt by Molmil](/molmil-images/mine/4qlt) | yCP in complex with tripeptidic epoxyketone inhibitor 2 (PR924) | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, N-[(3-methyl-1H-inden-2-yl)carbonyl]-D-alanyl-N-[(2S,4R)-5-hydroxy-4-methyl-3-oxo-1-phenylpentan-2-yl]-L-tryptophanamide, ... | Authors: | de Bruin, G, Huber, E, Xin, B, van Rooden, E, Al-Ayed, K, Kim, K, Kisselev, A, Driessen, C, van der Marel, G, Groll, M, Overkleeft, H. | Deposit date: | 2014-06-13 | Release date: | 2014-07-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure-based design of beta 1i or beta 5i specific inhibitors of human immunoproteasomes J.Med.Chem., 57, 2014
|
|
6AIT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ait by Molmil](/molmil-images/mine/6ait) | Crystal structure of E. coli BepA | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-barrel assembly-enhancing protease, ZINC ION | Authors: | Umar, M.S.M, Tanaka, Y, Kamikubo, H, Tsukazaki, T. | Deposit date: | 2018-08-24 | Release date: | 2018-12-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.598 Å) | Cite: | Structural Basis for the Function of the beta-Barrel Assembly-Enhancing Protease BepA. J. Mol. Biol., 431, 2019
|
|
6ALZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6alz by Molmil](/molmil-images/mine/6alz) | Crystal structure of Protein Phosphatase 1 bound to the natural inhibitor Tautomycetin | Descriptor: | (2Z)-2-[(1R)-3-{[(2R,3S,4R,7S,8S,11S,13R,16E)-17-ethyl-4,8-dihydroxy-3,7,11,13-tetramethyl-6,15-dioxononadeca-16,18-dien-2-yl]oxy}-1-hydroxy-3-oxopropyl]-3-methylbut-2-enedioic acid, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | Authors: | Choy, M.S, Peti, W, Page, R. | Deposit date: | 2017-08-08 | Release date: | 2017-11-29 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.208 Å) | Cite: | PP1:Tautomycetin Complex Reveals a Path toward the Development of PP1-Specific Inhibitors. J. Am. Chem. Soc., 139, 2017
|
|
6APC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6apc by Molmil](/molmil-images/mine/6apc) | Crystal Structure of Infant Antibody ADI-19425 | Descriptor: | Epididymis luminal protein 214, IGL@ protein, SULFATE ION | Authors: | Gilman, M.S.A, McLellan, J.S. | Deposit date: | 2017-08-17 | Release date: | 2018-03-21 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Infants Infected with Respiratory Syncytial Virus Generate Potent Neutralizing Antibodies that Lack Somatic Hypermutation. Immunity, 48, 2018
|
|
4OIZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4oiz by Molmil](/molmil-images/mine/4oiz) | Structure, interactions and evolutionary implications of a domain-swapped lectin dimer from Mycobacterium smegmatis | Descriptor: | LysM domain protein, methyl alpha-D-mannopyranoside | Authors: | Patra, D, Mishra, P, Surolia, A, Vijayan, M. | Deposit date: | 2014-01-20 | Release date: | 2014-07-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structure, interactions and evolutionary implications of a domain-swapped lectin dimer from Mycobacterium smegmatis. Glycobiology, 24, 2014
|
|
4OYM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4oym by Molmil](/molmil-images/mine/4oym) | Human solAC Complexed with (4-Amino-furazan-3-yl)-(3-methoxy-phenyl)-methanone | Descriptor: | (4-azanyl-1,2,5-oxadiazol-3-yl)-(3-methoxyphenyl)methanone, Adenylate cyclase type 10, GLYCEROL | Authors: | Vinkovic, M. | Deposit date: | 2014-02-12 | Release date: | 2014-04-02 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket. Chemmedchem, 9, 2014
|
|
4OYX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4oyx by Molmil](/molmil-images/mine/4oyx) | Human solAC Complexed with AMPCPP | Descriptor: | Adenylate cyclase type 10, CALCIUM ION, CHLORIDE ION, ... | Authors: | Vinkovic, M. | Deposit date: | 2014-02-13 | Release date: | 2014-04-02 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket. Chemmedchem, 9, 2014
|
|
7YKF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ykf by Molmil](/molmil-images/mine/7ykf) | Crystal structure of MAGI2 PDZ0-GK/pEphexin4 complex | Descriptor: | Ephexin4, Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 | Authors: | Zhang, M, Lin, L, Zhu, J. | Deposit date: | 2022-07-22 | Release date: | 2023-08-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs. Sci Adv, 9, 2023
|
|
4QLQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4qlq by Molmil](/molmil-images/mine/4qlq) | yCP in complex with tripeptidic epoxyketone inhibitor 8 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, N-(morpholin-4-ylacetyl)-L-alanyl-N-[(2S,4R)-1-cyclohexyl-5-hydroxy-4-methyl-3-oxopentan-2-yl]-O-methyl-L-tyrosinamide, ... | Authors: | De Bruin, G, Huber, E, Xin, B, Van Rooden, E, Al-Ayed, K, Kim, K, Kisselev, A, Driessen, C, Van der Marel, G, Groll, M, Overkleeft, H. | Deposit date: | 2014-06-13 | Release date: | 2014-07-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure-based design of beta 1i or beta 5i specific inhibitors of human immunoproteasomes J.Med.Chem., 57, 2014
|
|
7YKI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7yki by Molmil](/molmil-images/mine/7yki) | Crystal structure of MAGI2 PDZ0-GK domain in complex with phospho-SAPAP1 GBR3 peptide | Descriptor: | GLYCEROL, Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, ... | Authors: | Zhang, M, Lin, L, Zhu, J. | Deposit date: | 2022-07-22 | Release date: | 2023-08-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs. Sci Adv, 9, 2023
|
|
4QLY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4qly by Molmil](/molmil-images/mine/4qly) | Crystal structure of CLA-ER, a novel enone reductase catalyzing a key step of a gut-bacterial fatty acid saturation metabolism, biohydrogenation | Descriptor: | Enone reductase CLA-ER, FLAVIN MONONUCLEOTIDE | Authors: | Hou, F, Miyakawa, T, Tanokura, M. | Deposit date: | 2014-06-13 | Release date: | 2015-02-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.005 Å) | Cite: | Structure and reaction mechanism of a novel enone reductase. Febs J., 282, 2015
|
|
7YKG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ykg by Molmil](/molmil-images/mine/7ykg) | Crystal structure of MAGI2 PDZ0-GK/pSGEF complex | Descriptor: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, SGEF | Authors: | Zhang, M, Lin, L, Zhu, J. | Deposit date: | 2022-07-22 | Release date: | 2023-08-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs. Sci Adv, 9, 2023
|
|
7YKH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ykh by Molmil](/molmil-images/mine/7ykh) | Crystal structure of MAGI2 PDZ0-GK domain in complex with phospho-SAPAP1 GBR2 peptide | Descriptor: | GLYCEROL, Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, ... | Authors: | Zhang, M, Lin, L, Zhu, J. | Deposit date: | 2022-07-22 | Release date: | 2023-08-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs. Sci Adv, 9, 2023
|
|
4QCI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4qci by Molmil](/molmil-images/mine/4qci) | PDGF-B blocking antibody bound to PDGF-BB | Descriptor: | Platelet-derived growth factor subunit B, anti-PDGF-BB antibody - Light Chain, anti-PDGF-BB antibody - Heavy chain | Authors: | Kuai, J, Mosyak, L, Tam, M, LaVallie, E, Pullen, N, Carven, G. | Deposit date: | 2014-05-12 | Release date: | 2015-03-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Characterization of Binding Mode of Action of a Blocking Anti-Platelet-Derived Growth Factor (PDGF)-B Monoclonal Antibody, MOR8457, Reveals Conformational Flexibility and Avidity Needed for PDGF-BB To Bind PDGF Receptor-beta. Biochemistry, 54, 2015
|
|
4O16
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4o16 by Molmil](/molmil-images/mine/4o16) | Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors | Descriptor: | 1,2-ETHANEDIOL, 6-({4-[(3,5-difluorophenyl)sulfonyl]benzyl}carbamoyl)-1-(5-O-phosphono-beta-D-ribofuranosyl)imidazo[1,2-a]pyridin-1-ium, Nicotinamide phosphoribosyltransferase, ... | Authors: | Oh, A, Coons, M, Brillantes, B, Wang, W. | Deposit date: | 2013-12-15 | Release date: | 2014-10-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.783 Å) | Cite: | Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors. Plos One, 9, 2014
|
|
4NLF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4nlf by Molmil](/molmil-images/mine/4nlf) | |
4QLV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4qlv by Molmil](/molmil-images/mine/4qlv) | yCP in complex with tripeptidic epoxyketone inhibitor 17 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, N-(morpholin-4-ylacetyl)-D-alanyl-N-[(2S,4R)-5-hydroxy-4-methyl-3-oxo-1-phenylpentan-2-yl]-O-methyl-L-tyrosinamide, ... | Authors: | de Bruin, G, Huber, E, Xin, B, van Rooden, E, Al-Ayed, K, Kim, K, Kisselev, A, Driessen, C, van der Marel, G, Groll, M, Overkleeft, H. | Deposit date: | 2014-06-13 | Release date: | 2014-07-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure-based design of beta 1i or beta 5i specific inhibitors of human immunoproteasomes J.Med.Chem., 57, 2014
|
|
4QGN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4qgn by Molmil](/molmil-images/mine/4qgn) | Human acireductone dioxygenase with iron ion and L-methionine in active center | Descriptor: | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, ACETATE ION, CHLORIDE ION, ... | Authors: | Milaczewska, A.M, Chruszcz, M, Petkowski, J.J, Niedzialkowska, E, Minor, W, Borowski, T. | Deposit date: | 2014-05-23 | Release date: | 2015-05-27 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | On the Structure and Reaction Mechanism of Human Acireductone Dioxygenase. Chemistry, 24, 2018
|
|
4QLS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4qls by Molmil](/molmil-images/mine/4qls) | yCP in complex with tripeptidic epoxyketone inhibitor 11 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, N-(morpholin-4-ylacetyl)-D-alanyl-N-[(2S,4R)-1-cyclohexyl-5-hydroxy-4-methyl-3-oxopentan-2-yl]-O-methyl-L-tyrosinamide, ... | Authors: | De Bruin, G, Huber, E, Xin, B, Van Rooden, E, Al-Ayed, K, Kim, K, Kisselev, A, Driessen, C, Van der Marel, G, Groll, M, Overkleeft, H. | Deposit date: | 2014-06-13 | Release date: | 2014-07-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure-based design of beta 1i or beta 5i specific inhibitors of human immunoproteasomes J.Med.Chem., 57, 2014
|
|
4QNH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4qnh by Molmil](/molmil-images/mine/4qnh) | Calcium-calmodulin (T79D) complexed with the calmodulin binding domain from a small conductance potassium channel SK2-a | Descriptor: | CALCIUM ION, Calmodulin, SULFATE ION, ... | Authors: | Zhang, M, Pascal, J.M, Logothetis, D.E, Zhang, J.F. | Deposit date: | 2014-06-17 | Release date: | 2014-08-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Selective phosphorylation modulates the PIP2 sensitivity of the CaM-SK channel complex. Nat.Chem.Biol., 10, 2014
|
|
4NBQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4nbq by Molmil](/molmil-images/mine/4nbq) | Structure of the polynucleotide phosphorylase (CBU_0852) from Coxiella burnetii | Descriptor: | Polyribonucleotide nucleotidyltransferase, SULFATE ION | Authors: | Rudolph, M.J, Cheung, J, Franklin, M.C, Cassidy, M, Gary, E, Burshteyn, F, Love, J. | Deposit date: | 2013-10-23 | Release date: | 2015-06-17 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.9138 Å) | Cite: | Structural genomics for drug design against the pathogen Coxiella burnetii. Proteins, 83, 2015
|
|
4N3M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4n3m by Molmil](/molmil-images/mine/4n3m) | Joint neutron/X-ray structure of urate oxidase in complex with 8-azaxanthine | Descriptor: | 8-AZAXANTHINE, CHLORIDE ION, SODIUM ION, ... | Authors: | Oksanen, E, Blakeley, M.P, Budayova-Spano, M. | Deposit date: | 2013-10-07 | Release date: | 2014-02-05 | Last modified: | 2018-06-13 | Method: | NEUTRON DIFFRACTION (1.919 Å), X-RAY DIFFRACTION | Cite: | The neutron structure of urate oxidase resolves a long-standing mechanistic conundrum and reveals unexpected changes in protonation. Plos One, 9, 2014
|
|
4QTH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4qth by Molmil](/molmil-images/mine/4qth) | Crystal structure of anti-uPAR Fab 8B12 | Descriptor: | anti-uPAR antibody, heavy chain, light chain | Authors: | Zhao, B, Yuan, C, Luo, Z, Huang, M. | Deposit date: | 2014-07-08 | Release date: | 2015-02-25 | Last modified: | 2022-08-24 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Stabilizing a flexible interdomain hinge region harboring the SMB binding site drives uPAR into its closed conformation. J.Mol.Biol., 427, 2015
|
|
4QQB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4qqb by Molmil](/molmil-images/mine/4qqb) | Structural basis for the assembly of the SXL-UNR translation regulatory complex | Descriptor: | Protein sex-lethal, Upstream of N-ras, isoform A, ... | Authors: | Hennig, J, Popowicz, G.M, Sattler, M. | Deposit date: | 2014-06-27 | Release date: | 2014-09-03 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for the assembly of the Sxl-Unr translation regulatory complex. Nature, 515, 2014
|
|