4QGN

Human acireductone dioxygenase with iron ion and L-methionine in active center

Summary for 4QGN

Entry DOI	10.2210/pdb4qgn/pdb
Descriptor	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, FE (III) ION, CHLORIDE ION, ... (7 entities in total)
Functional Keywords	rmlc-like cupin, oxidoreductase, iron binding, 1, 2-dihydroxy-5-(methylthio)pent-1-en-3-one dioxygenase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: Q9BV57
Total number of polymer chains	1
Total formula weight	22566.85
Authors	Milaczewska, A.M.,Chruszcz, M.,Petkowski, J.J.,Niedzialkowska, E.,Minor, W.,Borowski, T. (deposition date: 2014-05-23, release date: 2015-05-27, Last modification date: 2023-12-06)
Primary citation	Milaczewska, A.,Kot, E.,Amaya, J.A.,Makris, T.M.,Zajac, M.,Korecki, J.,Chumakov, A.,Trzewik, B.,Kedracka-Krok, S.,Minor, W.,Chruszcz, M.,Borowski, T. On the Structure and Reaction Mechanism of Human Acireductone Dioxygenase. Chemistry, 24:5225-5237, 2018 Cited by PubMed: 29193386 DOI: 10.1002/chem.201704617 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.05 Å)

Structure validation