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4QGN

Human acireductone dioxygenase with iron ion and L-methionine in active center

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenasepolymer18321800.71UniProt (Q9BV57)
Pfam (PF03079)
Homo sapiens (human)Acireductone dioxygenase (Fe(2+)-requiring), ARD, Fe-ARD, Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1, MTCBP-1, Submergence-induced protein-like factor, Sip-L
2B
(A)
FE (III) IONnon-polymer55.81Chemie (FE)
3C, D
(A)
CHLORIDE IONnon-polymer35.52Chemie (CL)
4E
(A)
SELENOMETHIONINEnon-polymer196.11Chemie (MSE)
5F, G, H, I
(A)
SULFATE IONnon-polymer96.14Chemie (SO4)
6J
(A)
ACETATE IONnon-polymer59.01Chemie (ACT)
7K
(A)
waterwater18.026Chemie (HOH)
Sequence modifications
A: 1 - 179 (UniProt: Q9BV57)
PDBExternal DatabaseDetails
Gly -3-expression tag
Ala -2-expression tag
Ala -1-expression tag
Ala 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight21800.7
Non-Polymers*Number of molecules9
Total formula weight766.2
All*Total formula weight22566.8
*Water molecules are not included.

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PDB entries from 2026-01-14

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