4WBF
 
 | | Acinetobacter baumannii SDF NDK | | 分子名称: | Nucleoside diphosphate kinase | | 著者 | Hu, Y, Liu, Y. | | 登録日 | 2014-09-03 | | 公開日 | 2015-06-17 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | Structural and Functional Characterization of Acinetobacter baumannii Nucleoside Diphosphate Kinase
Prog.Biochem.Biophys., 42, 2015
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4XOH
 | | Mechanistic insights into anchorage of the contractile ring from yeast to humans | | 分子名称: | Division mal foutue 1 protein | | 著者 | Chen, Z, Wu, J.-Q, Wang, J, Guan, R, Sun, L, Lee, I.-J, Liu, Y, Chen, M. | | 登録日 | 2015-01-16 | | 公開日 | 2015-07-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.801 Å) | | 主引用文献 | Mechanistic insights into the anchorage of the contractile ring by anillin and mid1
Dev.Cell, 33, 2015
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4RZI
 | | Crystal structure of PhaB from Synechocystis sp. PCC 6803 | | 分子名称: | 3-ketoacyl-acyl carrier protein reductase | | 著者 | Xue, S, Liu, Y. | | 登録日 | 2014-12-22 | | 公開日 | 2015-09-30 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.891 Å) | | 主引用文献 | Structure-directed construction of a high-performance version of the enzyme FabG from the photosynthetic microorganism Synechocystis sp. PCC 6803.
Febs Lett., 589, 2015
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4XNR
 | | Vibrio Vulnificus Adenine Riboswitch Aptamer Domain, Synthesized by Position-selective Labeling of RNA (PLOR), in Complex with Adenine | | 分子名称: | ADENINE, MAGNESIUM ION, Vibrio Vulnificus Adenine Riboswitch | | 著者 | Zhang, J, Liu, Y, Wang, Y.-X, Ferre-D'Amare, A.R. | | 登録日 | 2015-01-16 | | 公開日 | 2015-05-06 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Synthesis and applications of RNAs with position-selective labelling and mosaic composition.
Nature, 522, 2015
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4XOI
 | | Structure of hsAnillin bound with RhoA(Q63L) at 2.1 Angstroms resolution | | 分子名称: | Actin-binding protein anillin, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Sun, L, Guan, R, Lee, I.-J, Liu, Y, Chen, M, Wang, J, Wu, J, Chen, Z. | | 登録日 | 2015-01-16 | | 公開日 | 2015-07-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.092 Å) | | 主引用文献 | Mechanistic insights into the anchorage of the contractile ring by anillin and mid1
Dev.Cell, 33, 2015
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4RZG
 | | Crystal Structure Analysis of the DNPA-bounded NUR77 Ligand binding Domain | | 分子名称: | GLYCEROL, Nuclear receptor subfamily 4 group A member 1, pentyl (3,5-dihydroxy-2-nonanoylphenyl)acetate | | 著者 | Li, F, Tian, X, Li, A, Li, L, Liu, Y, Chen, H, Wu, Q, Lin, T. | | 登録日 | 2014-12-21 | | 公開日 | 2015-03-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation.
Nat.Chem.Biol., 11, 2015
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5OFB
 | | Crystal structure of human MORC2 (residues 1-603) with spinal muscular atrophy mutation S87L | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, MORC family CW-type zinc finger protein 2, ... | | 著者 | Douse, C.H, Liu, Y, Modis, Y. | | 登録日 | 2017-07-10 | | 公開日 | 2018-02-14 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Neuropathic MORC2 mutations perturb GHKL ATPase dimerization dynamics and epigenetic silencing by multiple structural mechanisms.
Nat Commun, 9, 2018
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5OFA
 | | Crystal structure of human MORC2 (residues 1-603) with spinal muscular atrophy mutation T424R | | 分子名称: | MAGNESIUM ION, MORC family CW-type zinc finger protein 2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Douse, C.H, Liu, Y, Modis, Y. | | 登録日 | 2017-07-10 | | 公開日 | 2018-02-14 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Neuropathic MORC2 mutations perturb GHKL ATPase dimerization dynamics and epigenetic silencing by multiple structural mechanisms.
Nat Commun, 9, 2018
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8WYI
 | | T cell receptor delta 2 gamma 9 with TCRD TM domain chimera of TRAC | | 分子名称: | Signal peptide,flag tag,T cell receptor delta variable 2,T cell receptor delta constant,T cell receptor alpha chain constant,T cell receptor delta variable 2,T cell receptor delta constant,T cell receptor alpha chain constant, Signal peptide,flag tag,T cell receptor gamma variable 9,T cell receptor gamma constant 1,T cell receptor gamma variable 9,T cell receptor gamma constant 1, T-cell surface glycoprotein CD3 delta chain, ... | | 著者 | Xin, W, Huang, B, Chi, X, Liu, Y, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q. | | 登録日 | 2023-10-31 | | 公開日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structures of human gamma delta T cell receptor-CD3 complex.
Nature, 2024
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8WY0
 | | T cell receptor delta 2 gamma 9 with F283A, F290A, and F291A | | 分子名称: | CHOLESTEROL, Signal peptide,flag tag,T cell receptor delta variable 2,T cell receptor delta constant, Signal peptide,flag tag,T cell receptor gamma variable 9,T cell receptor gamma constant 1, ... | | 著者 | Xin, W, Huang, B, Chi, X, Liu, Y, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q. | | 登録日 | 2023-10-30 | | 公開日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structures of human gamma delta T cell receptor-CD3 complex.
Nature, 2024
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1M63
 | | Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes | | 分子名称: | CALCINEURIN B SUBUNIT ISOFORM 1, CALCIUM ION, CYCLOSPORIN A, ... | | 著者 | Huai, Q, Kim, H.-Y, Liu, Y, Zhao, Y, Mondragon, A, Liu, J.O, Ke, H. | | 登録日 | 2002-07-12 | | 公開日 | 2002-09-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal Structure of Calcineurin-Cyclophilin-Cyclosporin Shows Common But Distinct Recognition of Immunophilin-Drug Complexes
Proc.Natl.Acad.Sci.USA, 99, 2002
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1FU6
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1FU5
 | | NMR STRUCTURE OF THE N-SH2 DOMAIN OF THE P85 SUBUNIT OF PI3-KINASE COMPLEXED TO A DOUBLY PHOSPHORYLATED PEPTIDE DERIVED FROM POLYOMAVIRUS MIDDLE T ANTIGEN | | 分子名称: | DOUBLY PHOSPHORYLATED MIDDLE T ANTIGEN, PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY ALPHA SUBUNIT | | 著者 | Weber, T, Schaffhausen, B, Liu, Y, Guenther, U.L. | | 登録日 | 2000-09-14 | | 公開日 | 2001-02-21 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure of the N-SH2 of the p85 subunit of phosphoinositide 3-kinase complexed to a doubly phosphorylated peptide reveals a second phosphotyrosine binding site.
Biochemistry, 39, 2000
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1HCN
 | | STRUCTURE OF HUMAN CHORIONIC GONADOTROPIN AT 2.6 ANGSTROMS RESOLUTION FROM MAD ANALYSIS OF THE SELENOMETHIONYL PROTEIN | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HUMAN CHORIONIC GONADOTROPIN | | 著者 | Wu, H, Lustbader, J.W, Liu, Y, Canfield, R.E, Hendrickson, W.A. | | 登録日 | 1994-07-01 | | 公開日 | 1994-09-30 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of human chorionic gonadotropin at 2.6 A resolution from MAD analysis of the selenomethionyl protein.
Structure, 2, 1994
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1H2I
 | | Human Rad52 protein, N-terminal domain | | 分子名称: | DNA REPAIR PROTEIN RAD52 HOMOLOG | | 著者 | Singleton, M.R, Wentzell, L.M, Liu, Y, West, S.C, Wigley, D.B. | | 登録日 | 2002-08-09 | | 公開日 | 2002-10-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure of the Single-Strand Annealing Domain of Human Rad52 Protein
Proc.Natl.Acad.Sci.USA, 99, 2002
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1J4J
 | | Crystal Structure of Tabtoxin Resistance Protein (form II) complexed with an Acyl Coenzyme A | | 分子名称: | ACETYL COENZYME *A, TABTOXIN RESISTANCE PROTEIN | | 著者 | He, H, Ding, Y, Bartlam, M, Zhang, R, Duke, N, Joachimiak, A, Shao, Y, Cao, Z, Tang, H, Liu, Y, Jiang, F, Liu, J, Zhao, N, Rao, Z. | | 登録日 | 2001-10-02 | | 公開日 | 2003-06-03 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Crystal structure of tabtoxin resistance protein complexed with acetyl coenzyme A reveals the mechanism for beta-lactam acetylation.
J.Mol.Biol., 325, 2003
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8AH0
 | | BK Polyomavirus VP1 mutant VQQ | | 分子名称: | CHLORIDE ION, GLYCEROL, Major capsid protein VP1 | | 著者 | Sorin, M.N, Di Maio, A, Silva, L.M, Ebert, D, Delannoy, C, Nguyen, N.-K, Guerardel, Y, Chai, W, Halary, F, Renaudin-Autain, K, Liu, Y, Bressollette-Bodin, C, Stehle, T, McIlroy, D. | | 登録日 | 2022-07-20 | | 公開日 | 2023-02-22 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.798 Å) | | 主引用文献 | Structural and functional analysis of natural capsid variants suggests sialic acid-independent entry of BK polyomavirus.
Cell Rep, 42, 2023
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8AH1
 | | BK Polyomavirus VP1 mutant N-Q | | 分子名称: | CHLORIDE ION, GLYCEROL, Major capsid protein VP1 | | 著者 | Sorin, M.N, Di Maio, A, Silva, L.M, Ebert, D, Delannoy, C, Nguyen, N.-K, Guerardel, Y, Chai, W, Halary, F, Renaudin-Autain, K, Liu, Y, Bressollette-Bodin, C, Stehle, T, McIlroy, D. | | 登録日 | 2022-07-20 | | 公開日 | 2023-02-22 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.006 Å) | | 主引用文献 | Structural and functional analysis of natural capsid variants suggests sialic acid-independent entry of BK polyomavirus.
Cell Rep, 42, 2023
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8AGO
 | | BK Polyomavirus VP1 mutant E73Q | | 分子名称: | CHLORIDE ION, GLYCEROL, Major capsid protein VP1 | | 著者 | Sorin, M.N, Di Maio, A, Silva, L.M, Ebert, D, Delannoy, C, Nguyen, N.-K, Guerardel, Y, Chai, W, Halary, F, Renaudin-Autain, K, Liu, Y, Bressollette-Bodin, C, Stehle, T, McIlroy, D. | | 登録日 | 2022-07-20 | | 公開日 | 2023-02-22 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.853 Å) | | 主引用文献 | Structural and functional analysis of natural capsid variants suggests sialic acid-independent entry of BK polyomavirus.
Cell Rep, 42, 2023
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8AGH
 | | BK Polyomavirus VP1 mutant E73A | | 分子名称: | CHLORIDE ION, GLYCEROL, Major capsid protein VP1 | | 著者 | Sorin, M.N, Di Maio, A, Silva, L.M, Ebert, D, Delannoy, C, Nguyen, N.-K, Guerardel, Y, Chai, W, Halary, F, Renaudin-Autain, K, Liu, Y, Bressollette-Bodin, C, Stehle, T, McIlroy, D. | | 登録日 | 2022-07-20 | | 公開日 | 2023-02-22 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.887 Å) | | 主引用文献 | Structural and functional analysis of natural capsid variants suggests sialic acid-independent entry of BK polyomavirus.
Cell Rep, 42, 2023
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7LJD
 | | Allosteric modulator LY3154207 binding to dopamine-bound dopamine receptor 1 in complex with miniGs protein | | 分子名称: | 2-[2,6-bis(chloranyl)phenyl]-1-[(1S,3R)-3-(hydroxymethyl)-1-methyl-5-(3-methyl-3-oxidanyl-butyl)-3,4-dihydro-1H-isoquinolin-2-yl]ethanone, CHOLESTEROL, D(1A) dopamine receptor, ... | | 著者 | Zhuang, Y, Krumm, B, Zhang, H, Zhou, X.E, Wang, Y, Guo, J, Huang, X.-P, Liu, Y, Wang, L, Cheng, X, Jiang, Y, Jiang, H, Melcher, K, Zhang, C, Yi, W, Roth, B.L, Zhang, Y, Xu, H.E. | | 登録日 | 2021-01-28 | | 公開日 | 2021-03-03 | | 最終更新日 | 2021-05-12 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor.
Cell Res., 31, 2021
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1J48
 | | Crystal Structure of Apo-C1027 | | 分子名称: | Apoprotein of C1027 | | 著者 | Chen, Y, Li, J, Liu, Y, Bartlam, M, Gao, Y, Jin, L, Tang, H, Shao, Y, Zhen, Y, Rao, Z. | | 登録日 | 2001-07-30 | | 公開日 | 2003-06-03 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structure of Apo-C1027 and Computer Modeling Analysis of C1027 Chromophore- Protein Complex
To be published
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7KXT
 | | Crystal structure of human EED | | 分子名称: | 1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-benzimidazol-2-amine, Polycomb protein EED, UNKNOWN ATOM OR ION | | 著者 | Zhu, L, Dong, A, Du, D, Liu, Y, Luo, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2020-12-04 | | 公開日 | 2021-02-24 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction.
J.Med.Chem., 64, 2021
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5NP8
 | | PGK1 in complex with CRT0063465 (3-[2-(4-bromophenyl)-5,7-dimethyl-pyrazolo[1,5-a]pyrimidin-6-yl]propanoic acid) | | 分子名称: | 1,2-ETHANEDIOL, 3-PHOSPHOGLYCERIC ACID, 3-[2-(4-bromophenyl)-5,7-dimethyl-pyrazolo[1,5-a]pyrimidin-6-yl]propanoic acid, ... | | 著者 | Turnbull, A.P, Bilsland, A.E, Liu, Y, Sumpton, D, Stevenson, K, Cairney, C.J, Roffey, J, Jenkinson, D, Keith, W.N. | | 登録日 | 2017-04-13 | | 公開日 | 2018-05-16 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A Novel Pyrazolopyrimidine Ligand of Human PGK1 and Stress Sensor DJ1 Modulates the Shelterin Complex and Telomere Length Regulation.
Neoplasia, 21, 2019
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5LSK
 | | CRYSTAL STRUCTURE OF THE HUMAN KINETOCHORE MIS12-CENP-C COMPLEX | | 分子名称: | Centromere protein C, Kinetochore-associated protein DSN1 homolog, Kinetochore-associated protein NSL1 homolog, ... | | 著者 | Vetter, I.R, Petrovic, A, Keller, J, Liu, Y. | | 登録日 | 2016-09-02 | | 公開日 | 2016-11-16 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.502 Å) | | 主引用文献 | Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores.
Cell, 167, 2016
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