1FU6

NMR STRUCTURE OF THE N-SH2 DOMAIN OF THE P85 SUBUNIT OF PI3-KINASE

Summary for 1FU6

• Entry DOI: 10.2210/pdb1fu6/pdb
• Related: 1FU5
• Descriptor: PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY ALPHA SUBUNIT (1 entity in total)
• Functional Keywords: central beta-sheet with two flanking alpha-helices, protein binding
• Biological source: Rattus norvegicus (Norway rat)
• Total number of polymer chains: 1
• Total formula weight: 12870.38

Authors

Weber, T.,Schaffhausen, B.,Liu, Y.,Guenther, U.L. (deposition date: 2000-09-14, release date: 2001-02-21, Last modification date: 2022-02-23)

• Primary citation: Weber, T.,Schaffhausen, B.,Liu, Y.,Gunther, U.L.; NMR structure of the N-SH2 of the p85 subunit of phosphoinositide 3-kinase complexed to a doubly phosphorylated peptide reveals a second phosphotyrosine binding site.; Biochemistry, 39:15860-15869, 2000; PubMed: 11123912; DOI: 10.1021/bi001474d

Experimental method

SOLUTION NMR