4EWS
 
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6KKU
 | | human KCC1 structure determined in NaCl and GDN | | 分子名称: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | 著者 | Liu, S, Chang, S, Ye, S, Bai, X, Guo, J. | | 登録日 | 2019-07-27 | | 公開日 | 2019-10-23 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM structures of the human cation-chloride cotransporter KCC1.
Science, 366, 2019
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4F2A
 | | Crystal structure of cholestryl esters transfer protein in complex with inhibitors | | 分子名称: | (2R)-3-{[4-(4-chloro-3-ethylphenoxy)pyrimidin-2-yl][3-(1,1,2,2-tetrafluoroethoxy)benzyl]amino}-1,1,1-trifluoropropan-2-ol, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHLORIDE ION, ... | | 著者 | Liu, S, Qiu, X. | | 登録日 | 2012-05-07 | | 公開日 | 2012-09-05 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | | 主引用文献 | Crystal structures of cholesteryl ester transfer protein in complex with inhibitors.
J.Biol.Chem., 287, 2012
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3VEV
 | | Glucokinase in complex with an activator and glucose | | 分子名称: | (2S)-3-cyclopentyl-N-(5-methylpyridin-2-yl)-2-[2-oxo-4-(trifluoromethyl)pyridin-1(2H)-yl]propanamide, Glucokinase, SODIUM ION, ... | | 著者 | Liu, S. | | 登録日 | 2012-01-09 | | 公開日 | 2012-02-08 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Insights into Mechanism of Glucokinase Activation: OBSERVATION OF MULTIPLE DISTINCT PROTEIN CONFORMATIONS.
J.Biol.Chem., 287, 2012
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3VF6
 | | Glucokinase in complex with glucose and activator | | 分子名称: | 6-({(2S)-3-cyclopentyl-2-[4-(trifluoromethyl)-1H-imidazol-1-yl]propanoyl}amino)pyridine-3-carboxylic acid, Glucokinase, SODIUM ION, ... | | 著者 | Liu, S. | | 登録日 | 2012-01-09 | | 公開日 | 2012-02-08 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Insights into Mechanism of Glucokinase Activation: OBSERVATION OF MULTIPLE DISTINCT PROTEIN CONFORMATIONS.
J.Biol.Chem., 287, 2012
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3VEY
 | | glucokinase in complex with glucose and ATPgS | | 分子名称: | 6-methoxy-N-(1-methyl-1H-pyrazol-3-yl)quinazolin-4-amine, Glucokinase, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | 著者 | Liu, S. | | 登録日 | 2012-01-09 | | 公開日 | 2012-02-08 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Insights into Mechanism of Glucokinase Activation: OBSERVATION OF MULTIPLE DISTINCT PROTEIN CONFORMATIONS.
J.Biol.Chem., 287, 2012
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4Q9O
 | | Crystal structure of Upps + inhibitor | | 分子名称: | 3-(2-chlorophenyl)-5-methyl-N-[4-(propan-2-yl)phenyl]-1,2-oxazole-4-carboxamide, Isoprenyl transferase, SULFATE ION | | 著者 | Liu, S, Qiu, X. | | 登録日 | 2014-05-01 | | 公開日 | 2014-10-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Discovery and structural characterization of an allosteric inhibitor of bacterial cis-prenyltransferase.
Protein Sci., 24, 2015
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4QEB
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4QDV
 | | Dcps in complex with covalent ligand | | 分子名称: | 4-{[(2,4-diaminoquinazolin-5-yl)oxy]methyl}benzenesulfonic acid, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Liu, S. | | 登録日 | 2014-05-14 | | 公開日 | 2015-05-20 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Dcps in complex with covalent ligands targeting Tyrosines
To be Published
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4QDE
 | | Dcps in complex with covalent inhibitor | | 分子名称: | 2-{[(2,4-diaminoquinazolin-5-yl)oxy]methyl}benzenesulfonic acid, PHOSPHATE ION, m7GpppX diphosphatase | | 著者 | Liu, S. | | 登録日 | 2014-05-13 | | 公開日 | 2015-05-13 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Dcps in complex with covalent inhibitors
To be Published
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4Q9M
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2MA1
 | | Solution structure of HRDC1 domain of RecQ helicase from Deinococcus radiodurans | | 分子名称: | DNA helicase RecQ | | 著者 | Liu, S, Zhang, W, Gao, Z, Ming, Q, Hou, H, Lan, W, Wu, H, Cao, C, Dong, Y. | | 登録日 | 2013-06-24 | | 公開日 | 2013-07-10 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure of the N-terminal-most HRDC1 domain of RecQ helicase from Deinococcus radiodurans
To be Published
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4TN6
 | | CK1d in complex with inhibitor | | 分子名称: | 4-{4-(4-fluorophenyl)-1-[1-(1,2-oxazol-3-ylmethyl)piperidin-4-yl]-1H-imidazol-5-yl}pyrimidin-2-amine, Casein kinase I isoform delta, SULFATE ION | | 著者 | Liu, S. | | 登録日 | 2014-06-03 | | 公開日 | 2015-08-12 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | CK1D IN COMPLEX WITH inhibitor
To Be Published
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3SIU
 | | Structure of a hPrp31-15.5K-U4atac 5' stem loop complex, monomeric form | | 分子名称: | NHP2-like protein 1, SULFATE ION, U4/U6 small nuclear ribonucleoprotein Prp31, ... | | 著者 | Liu, S, Ghalei, H, Luhrmann, R, Wahl, M.C. | | 登録日 | 2011-06-20 | | 公開日 | 2011-08-10 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.626 Å) | | 主引用文献 | Structural basis for the dual U4 and U4atac snRNA-binding specificity of spliceosomal protein hPrp31.
Rna, 17, 2011
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2I80
 | | Allosteric inhibition of Staphylococcus aureus D-alanine:D-alanine ligase revealed by crystallographic studies | | 分子名称: | 3-CHLORO-2,2-DIMETHYL-N-[4-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE, D-alanine-D-alanine ligase | | 著者 | Liu, S, Chang, J.S, Herberg, J.T, Horng, M.-M, Tomich, P.K, Lin, A.H, Marotti, K.R. | | 登録日 | 2006-08-31 | | 公開日 | 2006-09-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Allosteric inhibition of Staphylococcus aureus D-alanine:D-alanine ligase revealed by crystallographic studies.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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2FYS
 | | Crystal structure of Erk2 complex with KIM peptide derived from MKP3 | | 分子名称: | Dual specificity protein phosphatase 6, Mitogen-activated protein kinase 1 | | 著者 | Liu, S, Sun, J.P, Zhou, B, Zhang, Z.Y. | | 登録日 | 2006-02-08 | | 公開日 | 2006-04-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis of docking interactions between ERK2 and MAP kinase phosphatase 3
Proc.Natl.Acad.Sci.Usa, 103, 2006
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3SIV
 | | Structure of a hPrp31-15.5K-U4atac 5' stem loop complex, dimeric form | | 分子名称: | NHP2-like protein 1, U4/U6 small nuclear ribonucleoprotein Prp31, U4atac snRNA | | 著者 | Liu, S, Ghalei, H, Luhrmann, R, Wahl, M.C. | | 登録日 | 2011-06-20 | | 公開日 | 2011-08-10 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.304 Å) | | 主引用文献 | Structural basis for the dual U4 and U4atac snRNA-binding specificity of spliceosomal protein hPrp31.
Rna, 17, 2011
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2I8C
 | | Allosteric inhibition of Staphylococcus aureus D-alanine:D-alanine ligase revealed by crystallographic studies | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, D-alanine-D-alanine ligase, MAGNESIUM ION, ... | | 著者 | Liu, S, Chang, J.S, Herberg, J.T, Horng, M, Tomich, P.K, Lin, A.H, Marotti, K.R. | | 登録日 | 2006-09-01 | | 公開日 | 2006-09-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | | 主引用文献 | Allosteric inhibition of Staphylococcus aureus D-alanine:D-alanine ligase revealed by crystallographic studies.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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2GV9
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5W4W
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2I87
 | | Allosteric inhibition of Staphylococcus aureus D-alanine:D-alanine ligase revealed by crystallographic studies | | 分子名称: | D-alanine-D-alanine ligase, SULFATE ION | | 著者 | Liu, S, Chang, J.S, Herberg, J.T, Horng, M, Tomich, P.K, Lin, A.H, Marotti, K.R. | | 登録日 | 2006-09-01 | | 公開日 | 2006-10-03 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Allosteric inhibition of Staphylococcus aureus D-alanine:D-alanine ligase revealed by crystallographic studies.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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4KIK
 | | Human IkB kinase beta | | 分子名称: | Inhibitor of nuclear factor kappa-B kinase subunit beta, K-252A | | 著者 | Liu, S, Mosyak, L. | | 登録日 | 2013-05-02 | | 公開日 | 2013-06-26 | | 最終更新日 | 2013-08-28 | | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | | 主引用文献 | Crystal Structure of a Human I kappa B Kinase beta Asymmetric Dimer.
J.Biol.Chem., 288, 2013
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4NV5
 | | C50A mutant of Synechococcus VKOR, C2 crystal form (dehydrated) | | 分子名称: | UBIQUINONE-10, VKORC1/thioredoxin domain protein | | 著者 | Liu, S, Cheng, W, Fowle Grider, R, Shen, G, Li, W. | | 登録日 | 2013-12-04 | | 公開日 | 2014-02-12 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Structures of an intramembrane vitamin K epoxide reductase homolog reveal control mechanisms for electron transfer.
Nat Commun, 5, 2014
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4NV6
 | | C212A mutant of Synechococcus VKOR | | 分子名称: | UBIQUINONE-10, VKORC1/thioredoxin domain protein | | 著者 | Liu, S, Cheng, W, Fowle Grider, R, Shen, G, Li, W. | | 登録日 | 2013-12-04 | | 公開日 | 2014-02-12 | | 実験手法 | X-RAY DIFFRACTION (4.19 Å) | | 主引用文献 | Structures of an intramembrane vitamin K epoxide reductase homolog reveal control mechanisms for electron transfer.
Nat Commun, 5, 2014
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4NV2
 | | C50A mutant of Synechococcus VKOR, C2221 crystal form | | 分子名称: | UBIQUINONE-10, VKORC1/thioredoxin domain protein | | 著者 | Liu, S, Cheng, W, Fowle Grider, R, Shen, G, Li, W. | | 登録日 | 2013-12-04 | | 公開日 | 2014-02-12 | | 実験手法 | X-RAY DIFFRACTION (3.61 Å) | | 主引用文献 | Structures of an intramembrane vitamin K epoxide reductase homolog reveal control mechanisms for electron transfer.
Nat Commun, 5, 2014
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