4QEB

Dcps in complex with covalent inhibitor targeting Tyrosine

Summary for 4QEB

• Entry DOI: 10.2210/pdb4qeb/pdb
• Related: 4QDE 4QDV
• Descriptor: m7GpppX diphosphatase, PHOSPHATE ION, 3-{[(2,4-diaminoquinazolin-5-yl)oxy]methyl}benzenesulfonic acid (3 entities in total)
• Functional Keywords: decapping scavenger enzyme, residual cap structure cleavage, mrna degradation, 3'->5' exosome-mediated mrna decay pathway, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: Q96C86
• Total number of polymer chains: 4
• Total formula weight: 155080.65

Authors

Liu, S. (deposition date: 2014-05-15, release date: 2015-05-20, Last modification date: 2024-10-30)

• Primary citation: Liu, S.; Human Dcps in complex with covalent inhibitor; To be Published,

Experimental method

X-RAY DIFFRACTION (3.21 Å)