4QEB
Dcps in complex with covalent inhibitor targeting Tyrosine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | m7GpppX diphosphatase | polymer | 337 | 38588.6 | 4 | UniProt (Q96C86) Pfam (PF05652) Pfam (PF11969) | Homo sapiens (human) | DCS-1, Decapping scavenger enzyme, Hint-related 7meGMP-directed hydrolase, Histidine triad nucleotide-binding protein 5, Histidine triad protein member 5, HINT-5, Scavenger mRNA-decapping enzyme DcpS |
| 2 | E, F, H, I (A, B, C) | PHOSPHATE ION | non-polymer | 95.0 | 4 | Chemie (PO4) | |||
| 3 | G (B) | 3-{[(2,4-diaminoquinazolin-5-yl)oxy]methyl}benzenesulfonic acid | non-polymer | 346.4 | 1 | Chemie (31G) |
Sequence modifications
A, B, C, D: 2 - 337 (UniProt: Q96C86)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 154354.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 726.2 | |
| All* | Total formula weight | 155080.7 |
