2I8C

Allosteric inhibition of Staphylococcus aureus D-alanine:D-alanine ligase revealed by crystallographic studies

Summary for 2I8C

Entry DOI	10.2210/pdb2i8c/pdb
Related	2I80 2I87
Descriptor	D-alanine-D-alanine ligase, SULFATE ION, ADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
Functional Keywords	d-alanine:d-alanine ligase, adp complex, staphylococcus aureus, lyase
Biological source	Staphylococcus aureus subsp. aureus
Cellular location	Cytoplasm (By similarity): Q5HEB7
Total number of polymer chains	2
Total formula weight	83768.01
Authors	Liu, S.,Chang, J.S.,Herberg, J.T.,Horng, M.,Tomich, P.K.,Lin, A.H.,Marotti, K.R. (deposition date: 2006-09-01, release date: 2006-09-26, Last modification date: 2023-08-30)
Primary citation	Liu, S.,Chang, J.S.,Herberg, J.T.,Horng, M.M.,Tomich, P.K.,Lin, A.H.,Marotti, K.R. Allosteric inhibition of Staphylococcus aureus D-alanine:D-alanine ligase revealed by crystallographic studies. Proc.Natl.Acad.Sci.Usa, 103:15178-15183, 2006 Cited by PubMed: 17015835 DOI: 10.1073/pnas.0604905103 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.46 Å)

Structure validation