3VEV

Glucokinase in complex with an activator and glucose

Summary for 3VEV

• Entry DOI: 10.2210/pdb3vev/pdb
• Related: 3S41 3VEY 3VF6
• Descriptor: Glucokinase, alpha-D-glucopyranose, (2S)-3-cyclopentyl-N-(5-methylpyridin-2-yl)-2-[2-oxo-4-(trifluoromethyl)pyridin-1(2H)-yl]propanamide, ... (5 entities in total)
• Functional Keywords: catalysis reaction, transferase, transferase-transferase activator complex, transferase/transferase activator
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 53592.74

Authors

Liu, S. (deposition date: 2012-01-09, release date: 2012-02-08, Last modification date: 2023-09-13)

• Primary citation: Liu, S.,Ammirati, M.J.,Song, X.,Knafels, J.D.,Zhang, J.,Greasley, S.E.,Pfefferkorn, J.A.,Qiu, X.; Insights into Mechanism of Glucokinase Activation: OBSERVATION OF MULTIPLE DISTINCT PROTEIN CONFORMATIONS.; J.Biol.Chem., 287:13598-13610, 2012; PubMed: 22298776; DOI: 10.1074/jbc.M111.274126

Experimental method

X-RAY DIFFRACTION (1.8 Å)