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3VF6

Glucokinase in complex with glucose and activator

Summary for 3VF6
Entry DOI10.2210/pdb3vf6/pdb
Related3S41 3VEV 3VF6
DescriptorGlucokinase, alpha-D-glucopyranose, 6-({(2S)-3-cyclopentyl-2-[4-(trifluoromethyl)-1H-imidazol-1-yl]propanoyl}amino)pyridine-3-carboxylic acid, ... (5 entities in total)
Functional Keywordscatalysis reaction, transferase, transferase-transferase activator complex, transferase/transferase activator
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight53595.70
Authors
Liu, S. (deposition date: 2012-01-09, release date: 2012-02-08, Last modification date: 2024-02-28)
Primary citationLiu, S.,Ammirati, M.J.,Song, X.,Knafels, J.D.,Zhang, J.,Greasley, S.E.,Pfefferkorn, J.A.,Qiu, X.
Insights into Mechanism of Glucokinase Activation: OBSERVATION OF MULTIPLE DISTINCT PROTEIN CONFORMATIONS.
J.Biol.Chem., 287:13598-13610, 2012
Cited by
PubMed: 22298776
DOI: 10.1074/jbc.M111.274126
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.86 Å)
Structure validation

217705

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