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PDB: 86 results

7KEU
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BU of 7keu by Molmil
Cryo-EM structure of the Caspase-1-CARD:ASC-CARD octamer
Descriptor: Apoptosis-associated speck-like protein containing a CARD, Caspase-1
Authors:Hollingsworth, L.R, David, L, Li, Y, Ruan, J, Wu, H.
Deposit date:2020-10-12
Release date:2020-11-25
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes.
Nat Commun, 12, 2021
6XKK
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BU of 6xkk by Molmil
Cryo-EM structure of the NLRP1-CARD filament
Descriptor: NACHT, LRR and PYD domains-containing protein 1
Authors:Hollingsworth, L.R, David, L, Li, Y, Sharif, H, Fontana, P, Fu, T, Wu, H.
Deposit date:2020-06-26
Release date:2020-11-25
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes.
Nat Commun, 12, 2021
6XKJ
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BU of 6xkj by Molmil
Cryo-EM structure of CARD8-CARD filament
Descriptor: Caspase recruitment domain-containing protein 8
Authors:Hollingsworth, L.R, David, L, Li, Y, Sharif, H, Fontana, P, Fu, T, Wu, H.
Deposit date:2020-06-26
Release date:2020-11-25
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes.
Nat Commun, 12, 2021
4PXA
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BU of 4pxa by Molmil
DEAD-box RNA helicase DDX3X Cancer-associated mutant D354V
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DDX3X, PHOSPHATE ION
Authors:Epling, L.B, Grace, C.R, Lowe, B.R, Partridge, J.F, Enemark, E.J.
Deposit date:2014-03-22
Release date:2015-03-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Cancer-Associated Mutants of RNA Helicase DDX3X Are Defective in RNA-Stimulated ATP Hydrolysis.
J.Mol.Biol., 427, 2015
4PX9
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BU of 4px9 by Molmil
DEAD-box RNA helicase DDX3X Domain 1 with N-terminal ATP-binding Loop
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DDX3X
Authors:Epling, L.B, Grace, C.R, Lowe, B.R, Partridge, J.F, Enemark, E.J.
Deposit date:2014-03-22
Release date:2015-03-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Cancer-Associated Mutants of RNA Helicase DDX3X Are Defective in RNA-Stimulated ATP Hydrolysis.
J.Mol.Biol., 427, 2015
6X6C
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BU of 6x6c by Molmil
Cryo-EM structure of NLRP1-DPP9-VbP complex
Descriptor: Dipeptidyl peptidase 9, NACHT, LRR and PYD domains-containing protein 1, ...
Authors:Hollingsworth, L.R, Sharif, H, Griswold, A.R, Fontana, P, Mintseris, J, Dagbay, K.B, Paulo, J.A, Gygi, S.P, Bachovchin, D.A, Wu, H.
Deposit date:2020-05-27
Release date:2021-03-10
Last modified:2021-05-12
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation.
Nature, 592, 2021
6X6A
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BU of 6x6a by Molmil
Cryo-EM structure of NLRP1-DPP9 complex
Descriptor: Dipeptidyl peptidase 9, NACHT, LRR and PYD domains-containing protein 1
Authors:Hollingsworth, L.R, Sharif, H, Griswold, A.R, Fontana, P, Mintseris, J, Dagbay, K.B, Paulo, J.A, Gygi, S.P, Bachovchin, D.A, Wu, H.
Deposit date:2020-05-27
Release date:2021-03-10
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation.
Nature, 592, 2021
8K8T
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BU of 8k8t by Molmil
Structure of CUL3-RBX1-KLHL22 complex
Descriptor: Cullin-3, Kelch-like protein 22
Authors:Wang, W, Ling, L, Dai, Z, Zuo, P, Yin, Y.
Deposit date:2023-07-31
Release date:2024-05-22
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:A conserved N-terminal motif of CUL3 contributes to assembly and E3 ligase activity of CRL3 KLHL22.
Nat Commun, 15, 2024
8K9I
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BU of 8k9i by Molmil
Structure of CUL3-RBX1-KLHL22 complex without CUL3 NA motif
Descriptor: Cullin-3, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ...
Authors:Wang, W, Ling, L, Dai, Z, Zuo, P, Yin, Y.
Deposit date:2023-08-01
Release date:2024-05-29
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:A conserved N-terminal motif of CUL3 contributes to assembly and E3 ligase activity of CRL3 KLHL22.
Nat Commun, 15, 2024
2MAI
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BU of 2mai by Molmil
NMR structure of lassomycin
Descriptor: Lassomycin
Authors:Gavrish, E, Sit, C.S, Kandror, O, Spoering, A, Peoples, A, Ling, L, Fetterman, A, Hughes, D, Cao, S, Bissell, A, Torrey, H, Akopian, T, Mueller, A, Epstein, S, Goldberg, A, Clardy, J, Lewis, K.
Deposit date:2013-07-09
Release date:2014-05-07
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Lassomycin, a Ribosomally Synthesized Cyclic Peptide, Kills Mycobacterium tuberculosis by Targeting the ATP-Dependent Protease ClpC1P1P2.
Chem.Biol., 21, 2014
4WMY
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BU of 4wmy by Molmil
Structure of Human intelectin-1 in complex with allyl-beta-galactofuranose
Descriptor: CALCIUM ION, Intelectin-1, prop-2-en-1-yl beta-D-galactofuranoside
Authors:Wangkanont, K, Kiessling, L.L, Forest, K.T.
Deposit date:2014-10-09
Release date:2015-07-01
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Recognition of microbial glycans by human intelectin-1.
Nat.Struct.Mol.Biol., 22, 2015
4WMO
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BU of 4wmo by Molmil
Selenomethionine derivative of Xenopus laevis embryonic epidermal lectin carbohydrate-binding domain
Descriptor: CALCIUM ION, PENTAETHYLENE GLYCOL, XEEL protein
Authors:Wangkanont, K, Kiessling, L.L, Forest, K.T.
Deposit date:2014-10-09
Release date:2016-01-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of Xenopus Embryonic Epidermal Lectin Reveal a Conserved Mechanism of Microbial Glycan Recognition.
J.Biol.Chem., 291, 2016
5EQF
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BU of 5eqf by Molmil
Crystal structure of oxidized UDP-galactopyranose mutase from Corynebacterium diphtheriae with UDP bound in closed form
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, UDP-galactopyranose mutase, ...
Authors:Wangkanont, K, Kiessling, L.L, Forest, K.T.
Deposit date:2015-11-12
Release date:2016-11-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.145 Å)
Cite:Conformational Control of UDP-Galactopyranose Mutase Inhibition.
Biochemistry, 56, 2017
5EQD
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BU of 5eqd by Molmil
Structure of oxidized UDP-galactopyranose mutase from Mycobacterium smegmatis in complex with UDP in opened and closed form
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, NITRATE ION, SULFATE ION, ...
Authors:Wangkanont, K, Kiessling, L.L, Forest, K.T.
Deposit date:2015-11-12
Release date:2016-11-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structural dynamics of UDP-galactopyranose mutase from Mycobacterium smegmatis
to be published
2QW1
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BU of 2qw1 by Molmil
Glucose/galactose binding protein bound to 3-O-methyl D-glucose
Descriptor: 3-O-methyl-beta-D-glucopyranose, CALCIUM ION, D-galactose-binding periplasmic protein, ...
Authors:Borrok, M.J, Kiessling, L.L, Forest, K.T.
Deposit date:2007-08-09
Release date:2008-08-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure-based design of a periplasmic binding protein antagonist that prevents domain closure.
Acs Chem.Biol., 4, 2009
2FW0
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BU of 2fw0 by Molmil
Apo Open Form of Glucose/Galactose Binding Protein
Descriptor: CALCIUM ION, CITRIC ACID, D-galactose-binding periplasmic protein, ...
Authors:Borrok, M.J, Kiessling, L.L, Forest, K.T.
Deposit date:2006-01-31
Release date:2007-02-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Conformational changes of glucose/galactose-binding protein illuminated by open, unliganded, and ultra-high-resolution ligand-bound structures.
Protein Sci., 16, 2007
2FVY
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BU of 2fvy by Molmil
High Resolution Glucose Bound Crystal Structure of GGBP
Descriptor: ACETATE ION, CALCIUM ION, CARBON DIOXIDE, ...
Authors:Borrok, M.J, Kiessling, L.L, Forest, K.T.
Deposit date:2006-01-31
Release date:2007-02-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (0.92 Å)
Cite:Conformational changes of glucose/galactose-binding protein illuminated by open, unliganded, and ultra-high-resolution ligand-bound structures.
Protein Sci., 16, 2007
6YVR
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BU of 6yvr by Molmil
Crystal structure of the neurotensin receptor 1 in complex with the peptide full agonist NTS8-13
Descriptor: Neurotensin receptor type 1,Neurotensin receptor type 1,DARPin crystallisation chaperone, neurotensin NTS8-13 (full agonist), nonyl beta-D-glucopyranoside
Authors:Deluigi, M, Merklinger, L, Hilge, M, Ernst, P, Klipp, A, Klenk, C, Plueckthun, A.
Deposit date:2020-04-28
Release date:2021-02-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.458 Å)
Cite:Complexes of the neurotensin receptor 1 with small-molecule ligands reveal structural determinants of full, partial, and inverse agonism.
Sci Adv, 7, 2021
3MMJ
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BU of 3mmj by Molmil
Structure of the PTP-like phytase from Selenomonas ruminantium in complex with myo-inositol hexakisphosphate
Descriptor: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
Authors:Gruninger, R.J, Selinger, L.B, Mosimann, S.C.
Deposit date:2010-04-20
Release date:2011-06-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Substrate binding in protein-tyrosine phosphatase-like inositol polyphosphatases.
J.Biol.Chem., 287, 2012
4WMQ
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BU of 4wmq by Molmil
Structure of Human Intelectin-1
Descriptor: CALCIUM ION, Intelectin-1
Authors:Wangkanont, K, Kiessling, L.L, Forest, K.T.
Deposit date:2014-10-09
Release date:2015-07-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Recognition of microbial glycans by human intelectin-1.
Nat.Struct.Mol.Biol., 22, 2015
6Z4Q
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BU of 6z4q by Molmil
Crystal structure of the neurotensin receptor 1 in complex with the small-molecule inverse agonist SR142948A
Descriptor: 2-[[5-(2,6-dimethoxyphenyl)-1-[4-[3-(dimethylamino)propyl-methyl-carbamoyl]-2-propan-2-yl-phenyl]pyrazol-3-yl]carbonylamino]adamantane-2-carboxylic acid, Neurotensin receptor type 1,Neurotensin receptor type 1,DARPin
Authors:Deluigi, M, Klipp, A, Hilge, M, Merklinger, L, Klenk, C, Plueckthun, A.
Deposit date:2020-05-25
Release date:2021-02-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.923 Å)
Cite:Complexes of the neurotensin receptor 1 with small-molecule ligands reveal structural determinants of full, partial, and inverse agonism.
Sci Adv, 7, 2021
6ZIN
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BU of 6zin by Molmil
Crystal structure of the neurotensin receptor 1 in complex with the small molecule inverse agonist SR48692
Descriptor: 2-[[1-(7-chloranylquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazol-3-yl]carbonylamino]adamantane-2-carboxylic acid, Neurotensin receptor type 1,DARPin,HRV 3C protease recognition sequence
Authors:Deluigi, M, Klipp, A, Hilge, M, Merklinger, L, Klenk, C, Plueckthun, A.
Deposit date:2020-06-26
Release date:2021-02-10
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.639 Å)
Cite:Complexes of the neurotensin receptor 1 with small-molecule ligands reveal structural determinants of full, partial, and inverse agonism.
Sci Adv, 7, 2021
6Z8N
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BU of 6z8n by Molmil
Crystal structure of the neurotensin receptor 1 in complex with the small-molecule full agonist SRI-9829
Descriptor: (2~{S})-4-methyl-2-[(1-quinolin-8-ylsulfonylindol-3-yl)carbonylamino]pentanoic acid, Neurotensin receptor type 1,Neurotensin receptor type 1,Neurotensin receptor type 1,Neurotensin receptor type 1,Neurotensin receptor 1 (NTSR1),Neurotensin receptor 1 (NTSR1)
Authors:Deluigi, M, Klipp, A, Hilge, M, Merklinger, L, Klenk, C, Plueckthun, A.
Deposit date:2020-06-02
Release date:2021-02-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.803 Å)
Cite:Complexes of the neurotensin receptor 1 with small-molecule ligands reveal structural determinants of full, partial, and inverse agonism.
Sci Adv, 7, 2021
6Z4S
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BU of 6z4s by Molmil
Crystal structure of the neurotensin receptor 1 (NTSR1-H4bmx) in complex with the small molecule inverse agonist SR48692
Descriptor: 2-[[1-(7-chloranylquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazol-3-yl]carbonylamino]adamantane-2-carboxylic acid, Neurotensin receptor type 1,DARPin,HRV 3C protease recognition sequence
Authors:Deluigi, M, Klipp, A, Hilge, M, Merklinger, L, Klenk, C, Plueckthun, A.
Deposit date:2020-05-25
Release date:2021-02-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.707 Å)
Cite:Complexes of the neurotensin receptor 1 with small-molecule ligands reveal structural determinants of full, partial, and inverse agonism.
Sci Adv, 7, 2021
6Z66
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BU of 6z66 by Molmil
Crystal structure of apo-state neurotensin receptor 1
Descriptor: Neurotensin receptor type 1,Neurotensin receptor type 1,DARPin
Authors:Deluigi, M, Klipp, A, Hilge, M, Merklinger, L, Klenk, C, Plueckthun, A.
Deposit date:2020-05-27
Release date:2021-02-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.192 Å)
Cite:Complexes of the neurotensin receptor 1 with small-molecule ligands reveal structural determinants of full, partial, and inverse agonism.
Sci Adv, 7, 2021

 

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數據於2024-07-03公開中

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