4PXA
DEAD-box RNA helicase DDX3X Cancer-associated mutant D354V
Summary for 4PXA
Entry DOI | 10.2210/pdb4pxa/pdb |
Related | 4PX9 |
Descriptor | ATP-dependent RNA helicase DDX3X, ADENOSINE-5'-DIPHOSPHATE, PHOSPHATE ION (3 entities in total) |
Functional Keywords | dead-box helicase, hydrolase, translation, rna binding protein |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus speckle: O00571 |
Total number of polymer chains | 1 |
Total formula weight | 53592.95 |
Authors | Epling, L.B.,Grace, C.R.,Lowe, B.R.,Partridge, J.F.,Enemark, E.J. (deposition date: 2014-03-22, release date: 2015-03-11, Last modification date: 2023-09-20) |
Primary citation | Epling, L.B.,Grace, C.R.,Lowe, B.R.,Partridge, J.F.,Enemark, E.J. Cancer-Associated Mutants of RNA Helicase DDX3X Are Defective in RNA-Stimulated ATP Hydrolysis. J.Mol.Biol., 427:1779-1796, 2015 Cited by PubMed: 25724843DOI: 10.1016/j.jmb.2015.02.015 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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