4PX9

DEAD-box RNA helicase DDX3X Domain 1 with N-terminal ATP-binding Loop

Summary for 4PX9

• Entry DOI: 10.2210/pdb4px9/pdb
• Related: 4PXA
• Descriptor: ATP-dependent RNA helicase DDX3X, ADENOSINE-5'-DIPHOSPHATE (2 entities in total)
• Functional Keywords: dead-box helicase, hydrolase, translation, rna binding protein
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus speckle: O00571
• Total number of polymer chains: 3
• Total formula weight: 100347.40

Authors

Epling, L.B.,Grace, C.R.,Lowe, B.R.,Partridge, J.F.,Enemark, E.J. (deposition date: 2014-03-22, release date: 2015-03-11, Last modification date: 2023-09-20)

• Primary citation: Epling, L.B.,Grace, C.R.,Lowe, B.R.,Partridge, J.F.,Enemark, E.J.; Cancer-Associated Mutants of RNA Helicase DDX3X Are Defective in RNA-Stimulated ATP Hydrolysis.; J.Mol.Biol., 427:1779-1796, 2015; PubMed: 25724843; DOI: 10.1016/j.jmb.2015.02.015

Experimental method

X-RAY DIFFRACTION (2.31 Å)