2Q0U
 
 | | Structure of Pectenotoxin-2 and Latrunculin B Bound to Actin | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, CALCIUM ION, ... | | Authors: | Allingham, J.S, Miles, C.O, Rayment, I. | | Deposit date: | 2007-05-22 | | Release date: | 2007-07-17 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | A structural basis for regulation of actin polymerization by pectenotoxins.
J.Mol.Biol., 371, 2007
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3F1R
 | | Crystal structure of FGF20 dimer | | Descriptor: | Fibroblast growth factor 20, SULFATE ION | | Authors: | Kalinina, J, Mohammadi, M. | | Deposit date: | 2008-10-28 | | Release date: | 2009-07-28 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Homodimerization controls the fibroblast growth factor 9 subfamily's receptor binding and heparan sulfate-dependent diffusion in the extracellular matrix
Mol.Cell.Biol., 29, 2009
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2QDI
 | | Drosophila OBP LUSH D118A mutation | | Descriptor: | General odorant-binding protein lush, TRIETHYLENE GLYCOL | | Authors: | Laughlin, J.D, Jones, D.N.M. | | Deposit date: | 2007-06-20 | | Release date: | 2008-06-03 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Activation of pheromone-sensitive neurons is mediated by conformational activation of pheromone-binding protein.
Cell(Cambridge,Mass.), 133, 2008
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1IKW
 | | Wild Type HIV-1 Reverse Transcriptase in Complex with Efavirenz | | Descriptor: | (-)-6-CHLORO-4-CYCLOPROPYLETHYNYL-4-TRIFLUOROMETHYL-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE, POL POLYPROTEIN | | Authors: | Lindberg, J, Unge, T. | | Deposit date: | 2001-05-07 | | Release date: | 2001-06-06 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural basis for the inhibitory efficacy of efavirenz (DMP-266), MSC194 and PNU142721 towards the HIV-1 RT K103N mutant.
Eur.J.Biochem., 269, 2002
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2MXO
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2MQF
 | | NMR structure of spider toxin-TRTX-Hhn2b | | Descriptor: | Mu-theraphotoxin-Hhn2b | | Authors: | Klint, J.K, Chin, Y.K.Y, Mobli, M. | | Deposit date: | 2014-06-19 | | Release date: | 2015-07-15 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Rational Engineering Defines a Molecular Switch That Is Essential for Activity of Spider-Venom Peptides against the Analgesics Target NaV1.7
Mol.Pharmacol., 88, 2015
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7LFF
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1LNZ
 | | Structure of the Obg GTP-binding protein | | Descriptor: | GUANOSINE-5',3'-TETRAPHOSPHATE, MAGNESIUM ION, SPO0B-associated GTP-binding protein | | Authors: | Buglino, J, Shen, V, Hakimian, P, Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2002-05-04 | | Release date: | 2002-09-16 | | Last modified: | 2021-02-03 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural and biochemical analysis of the Obg GTP binding protein
Structure, 10, 2002
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2O0A
 | | The structure of the C-terminal domain of Vik1 has a motor domain fold but lacks a nucleotide-binding site. | | Descriptor: | 1,2-ETHANEDIOL, S.cerevisiae chromosome XVI reading frame ORF YPL253c | | Authors: | Allingham, J.S, Sproul, L.R, Rayment, I, Gilbert, S.P. | | Deposit date: | 2006-11-27 | | Release date: | 2007-03-27 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Vik1 modulates microtubule-Kar3 interactions through a motor domain that lacks an active site.
Cell(Cambridge,Mass.), 128, 2007
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2R2M
 | | 2-(2-Chloro-6-Fluorophenyl)Acetamides as Potent Thrombin Inhibitors | | Descriptor: | Hirudin-3A, N-[2-({[amino(imino)methyl]amino}oxy)ethyl]-2-{6-chloro-3-[(2,2-difluoro-2-phenylethyl)amino]-2-fluorophenyl}acetamide, Thrombin heavy chain, ... | | Authors: | Spurlino, J. | | Deposit date: | 2007-08-27 | | Release date: | 2008-08-26 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | 2-(2-Chloro-6-Fluorophenyl)Acetamides as Potent Thrombin Inhibitors
Bioorg.Med.Chem.Lett., 17, 2007
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1DBY
 | | NMR STRUCTURES OF CHLOROPLAST THIOREDOXIN M CH2 FROM THE GREEN ALGA CHLAMYDOMONAS REINHARDTII | | Descriptor: | CHLOROPLAST THIOREDOXIN M CH2 | | Authors: | Lancelin, J.-M, Guilhaudis, L, Krimm, I, Blackledge, M.J, Marion, D. | | Deposit date: | 1999-11-03 | | Release date: | 1999-11-08 | | Last modified: | 2022-02-16 | | Method: | SOLUTION NMR | | Cite: | NMR structures of thioredoxin m from the green alga Chlamydomonas reinhardtii.
Proteins, 41, 2000
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1ANF
 | | MALTODEXTRIN BINDING PROTEIN WITH BOUND MALTOSE | | Descriptor: | MALTODEXTRIN-BINDING PROTEIN, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | Authors: | Spurlino, J.C, Quiocho, F.A. | | Deposit date: | 1997-06-25 | | Release date: | 1997-12-24 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | Extensive features of tight oligosaccharide binding revealed in high-resolution structures of the maltodextrin transport/chemosensory receptor.
Structure, 5, 1997
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2XGA
 | | MTSL spin-labelled Shigella Flexneri Spa15 | | Descriptor: | S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, SURFACE PRESENTATION OF ANTIGENS PROTEIN SPAK | | Authors: | Lillington, J.E.D, Johnson, S, Lea, S.M. | | Deposit date: | 2010-06-02 | | Release date: | 2010-12-01 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Shigella Flexneri Spa15 Crystal Structure Verified in Solution by Double Electron Electron Resonance.
J.Mol.Biol., 405, 2011
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1DEN
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1DEM
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2GTE
 | | Drosophila OBP LUSH bound to attractant pheromone 11-cis-vaccenyl acetate | | Descriptor: | (Z)-OCTADEC-11-ENYL ACETATE, General odorant-binding protein lush, PHOSPHATE ION | | Authors: | Laughlin, J.D, Ha, T, Smith, D.P, Jones, D.N.M. | | Deposit date: | 2006-04-27 | | Release date: | 2007-06-12 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Activation of pheromone-sensitive neurons is mediated by conformational activation of pheromone-binding protein
Cell(Cambridge,Mass.), 133, 2008
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5VY9
 | | S. cerevisiae Hsp104:casein complex, Middle Domain Conformation | | Descriptor: | Alpha-S1-casein, Heat shock protein 104, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | | Authors: | Gates, S.N, Yokom, A.L, Lin, J.-B, Jackrel, M.E, Rizo, A.N, Kendsersky, N.M, Buell, C.E, Sweeny, E.A, Chuang, E, Torrente, M.P, Mack, K.L, Su, M, Shorter, J, Southworth, D.R. | | Deposit date: | 2017-05-24 | | Release date: | 2017-07-19 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (6.7 Å) | | Cite: | Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104.
Science, 357, 2017
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4W2E
 | | Crystal structure of Elongation Factor 4 (EF4/LepA) bound to the Thermus thermophilus 70S ribosome | | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Gagnon, M.G, Lin, J, Steitz, T.A. | | Deposit date: | 2014-06-04 | | Release date: | 2014-10-01 | | Last modified: | 2023-07-26 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal structure of elongation factor 4 bound to a clockwise ratcheted ribosome.
Science, 345, 2014
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2GAS
 | | Crystal Structure of Isoflavone Reductase | | Descriptor: | isoflavone reductase | | Authors: | Wang, X, He, X, Lin, J, Shao, H, Chang, Z, Dixon, R.A. | | Deposit date: | 2006-03-09 | | Release date: | 2006-04-25 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal Structure of Isoflavone Reductase from Alfalfa (Medicago sativa L.)
J.Mol.Biol., 358, 2006
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8W7H
 | | Purine Nucleoside Phosphorylase in complex with MMV000848 | | Descriptor: | (2R)-1-(9H-carbazol-9-yl)-3-(cyclopentylamino)propan-2-ol, 1,2-ETHANEDIOL, PHOSPHATE ION, ... | | Authors: | Chung, Z, Lin, J.Q, Lescar, J. | | Deposit date: | 2023-08-30 | | Release date: | 2024-01-17 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Identification and structural validation of purine nucleoside phosphorylase from Plasmodium falciparum as a target of MMV000848.
J.Biol.Chem., 300, 2023
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6LPF
 | | The crystal structure of human cytoplasmic LRS | | Descriptor: | 2'-(L-NORVALYL)AMINO-2'-DEOXYADENOSINE, 5'-O-(L-leucylsulfamoyl)adenosine, GLYCEROL, ... | | Authors: | Liu, R.J, Long, T, Li, H, Li, J, Zhao, J.H, Lin, J.Z, Palencia, A, Wang, M.Z, Cusack, S, Wang, E.D. | | Deposit date: | 2020-01-10 | | Release date: | 2020-03-25 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.49 Å) | | Cite: | Molecular basis of the multifaceted functions of human leucyl-tRNA synthetase in protein synthesis and beyond.
Nucleic Acids Res., 48, 2020
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7DFB
 | | Crystal of Arrestin2-V2Rpp-6-7-Fab30 complex | | Descriptor: | Beta-arrestin-1, FAB30 HEAVY CHAIN, FAB30 LIGHT CHAIN, ... | | Authors: | Sun, J.P, Yu, X, Xiao, P, He, Q.T, Lin, J.Y, Zhu, Z.L. | | Deposit date: | 2020-11-06 | | Release date: | 2021-07-28 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.28 Å) | | Cite: | Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2.
Nat Commun, 12, 2021
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7DF9
 | | Crystal of Arrestin2-V2Rpp-1-Fab30 complex | | Descriptor: | Beta-arrestin-1, FAB30 HEAVY CHAIN, FAB30 LIGHT CHAIN, ... | | Authors: | Sun, J.P, Yu, X, Xiao, P, He, Q.T, Lin, J.Y, Zhu, Z.L. | | Deposit date: | 2020-11-06 | | Release date: | 2021-07-28 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.17 Å) | | Cite: | Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2.
Nat Commun, 12, 2021
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7DFA
 | | Crystal of Arrestin2-V2Rpp-4-Fab30 complex | | Descriptor: | Beta-arrestin-1, FAB30 HEAVY CHAIN, FAB30 LIGHT CHAIN, ... | | Authors: | Sun, J.P, Yu, X, Xiao, P, He, Q.T, Lin, J.Y, Zhu, Z.L. | | Deposit date: | 2020-11-06 | | Release date: | 2021-07-28 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.54 Å) | | Cite: | Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2.
Nat Commun, 12, 2021
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7DFC
 | | Crystal of Arrestin2-V2Rpp-3-Fab30 complex | | Descriptor: | Beta-arrestin-1, FAB30 HEAVY CHAIN, FAB30 LIGHT CHAIN, ... | | Authors: | Sun, J.P, Yu, X, Xiao, P, He, Q.T, Lin, J.Y, Zhu, Z.L. | | Deposit date: | 2020-11-06 | | Release date: | 2021-07-28 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.49 Å) | | Cite: | Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2.
Nat Commun, 12, 2021
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