2Q0U

Structure of Pectenotoxin-2 and Latrunculin B Bound to Actin

Summary for 2Q0U

Entry DOI	10.2210/pdb2q0u/pdb
Related	1ESV 1IJJ 1QZ5 1YXQ 2ASM 2FXU
Descriptor	Actin, CALCIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
Functional Keywords	pectenotoxin, latrunculin b, actin, anti-tumor, filament capping, natural product, cytotoxin, macrolide, structural protein
Biological source	Oryctolagus cuniculus (rabbit)
Cellular location	Cytoplasm, cytoskeleton: P68135
Total number of polymer chains	1
Total formula weight	43715.52
Authors	Allingham, J.S.,Miles, C.O.,Rayment, I. (deposition date: 2007-05-22, release date: 2007-07-17, Last modification date: 2023-08-30)
Primary citation	Allingham, J.S.,Miles, C.O.,Rayment, I. A structural basis for regulation of actin polymerization by pectenotoxins. J.Mol.Biol., 371:959-970, 2007 Cited by PubMed: 17599353 DOI: 10.1016/j.jmb.2007.05.056 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.45 Å)

Structure validation