6JI3
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![BU of 6ji3 by Molmil](/molmil-images/mine/6ji3) | BRD4-BD1 bound with ligand 103 | 分子名称: | (3~{R})-4-cyclopropyl-1,3-dimethyl-6-(1~{H}-pyrrol-2-yl)-3~{H}-quinoxalin-2-one, Bromodomain-containing protein 4 | 著者 | Cao, D.Y, Li, Y.L, Du, Z.Y, Li, J, Xiong, B. | 登録日 | 2019-02-20 | 公開日 | 2020-02-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | brd4-bd1 bound with ligand 103 To Be Published
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3D2R
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![BU of 3d2r by Molmil](/molmil-images/mine/3d2r) | Crystal structure of pyruvate dehydrogenase kinase isoform 4 in complex with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | 著者 | Kato, M, Wynn, R.M, Chuang, L.C, Tso, S.-C, Li, J, Chuang, D.T. | 登録日 | 2008-05-08 | 公開日 | 2008-08-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Pyruvate Dehydrogenase Kinase-4 Structures Reveal a Metastable Open Conformation Fostering Robust Core-free Basal Activity. J.Biol.Chem., 283, 2008
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1Z5T
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![BU of 1z5t by Molmil](/molmil-images/mine/1z5t) | Crystal Structure of [d(CGCGAA(Z3dU)(Z3dU)CGCG)]2, Z3dU:5-(3-aminopropyl)-2'-deoxyuridine, in presence of thallium I. | 分子名称: | 5'-D(*CP*GP*CP*GP*AP*AP*(ZDU)P*(ZDU)P*CP*GP*CP*G)-3', SPERMINE, THALLIUM (I) ION | 著者 | Moulaei, T, Maehigashi, T, Lountos, G.T, Komeda, S, Watkins, D, Stone, M.P, Marky, L.A, Li, J.S, Gold, B, Williams, L.D. | 登録日 | 2005-03-19 | 公開日 | 2005-07-26 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure of B-DNA with cations tethered in the major groove. Biochemistry, 44, 2005
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8IU2
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![BU of 8iu2 by Molmil](/molmil-images/mine/8iu2) | Cryo-EM structure of Long-wave-sensitive opsin 1 | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Peng, Q, Cheng, X.Y, Li, J, Lu, Q.Y, Li, Y.Y, Zhang, J. | 登録日 | 2023-03-23 | 公開日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | 主引用文献 | Cryo-EM structure of Long-wave-sensitive opsin 1 To Be Published
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5JHG
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![BU of 5jhg by Molmil](/molmil-images/mine/5jhg) | Crystal structure of the complex between the human RhoA and the DH/PH domain of human ARHGEF11 | 分子名称: | GLYCEROL, Rho guanine nucleotide exchange factor 11, Transforming protein RhoA | 著者 | Wang, R, Chen, Q, Zhang, H, Yan, Z, Li, J, Miao, L, Wang, F. | 登録日 | 2016-04-21 | 公開日 | 2017-04-26 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystallization and preliminary X-ray crystallographic analysis of a small GTPase RhoA bound with its inhibitor and ARHGEF11 To Be Published
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6JI4
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![BU of 6ji4 by Molmil](/molmil-images/mine/6ji4) | brd4-bd1 bound with ligand 138 | 分子名称: | (3R)-4-cyclopropyl-1,3-dimethyl-6-[5-methyl-4-(4-methylphenyl)-4H-1,2,4-triazol-3-yl]-3,4-dihydroquinoxalin-2(1H)-one, Bromodomain-containing protein 4 | 著者 | Cao, D.Y, Li, Y.L, Du, Z.Y, Li, J, Xiong, B. | 登録日 | 2019-02-20 | 公開日 | 2020-02-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | brd4-bd1 bound with ligand 138 To Be Published
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6LTJ
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![BU of 6ltj by Molmil](/molmil-images/mine/6ltj) | Structure of nucleosome-bound human BAF complex | 分子名称: | AT-rich interactive domain-containing protein 1A, Actin, cytoplasmic 1, ... | 著者 | He, S, Wu, Z, Tian, Y, Yu, Z, Yu, J, Wang, X, Li, J, Liu, B, Xu, Y. | 登録日 | 2020-01-22 | 公開日 | 2020-02-12 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structure of nucleosome-bound human BAF complex. Science, 367, 2020
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5GVA
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![BU of 5gva by Molmil](/molmil-images/mine/5gva) | WD40 domain of human AND-1 | 分子名称: | WD repeat and HMG-box DNA-binding protein 1 | 著者 | Guan, C.C, Li, J. | 登録日 | 2016-09-04 | 公開日 | 2017-04-19 | 最終更新日 | 2017-06-21 | 実験手法 | X-RAY DIFFRACTION (1.851 Å) | 主引用文献 | The structure and polymerase-recognition mechanism of the crucial adaptor protein AND-1 in the human replisome J. Biol. Chem., 292, 2017
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6JI5
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![BU of 6ji5 by Molmil](/molmil-images/mine/6ji5) | brd4-bd1 bound with ligand 167 | 分子名称: | (3R)-4-cyclopentyl-6-[1-(2,4-dimethylphenyl)-3-(4-methylpiperazine-1-carbonyl)-1H-1,2,4-triazol-5-yl]-1,3-dimethyl-3,4-dihydroquinoxalin-2(1H)-one, Bromodomain-containing protein 4 | 著者 | Cao, D.Y, Li, Y.L, Du, Z.Y, Li, J, Xiong, B. | 登録日 | 2019-02-20 | 公開日 | 2020-02-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | brd4-bd1 bound with ligand 167 To Be Published
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2KRG
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![BU of 2krg by Molmil](/molmil-images/mine/2krg) | Solution Structure of human sodium/ hydrogen exchange regulatory factor 1(150-358) | 分子名称: | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 | 著者 | Bhattacharya, S, Dai, Z, Li, J, Baxter, S, Callaway, D.J.E, Cowburn, D, Bu, Z. | 登録日 | 2009-12-17 | 公開日 | 2009-12-29 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | A conformational switch in the scaffolding protein NHERF1 controls autoinhibition and complex formation. J.Biol.Chem., 285, 2010
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6JRL
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![BU of 6jrl by Molmil](/molmil-images/mine/6jrl) | Crystal structure of Drosophila alpha methyldopa-resistant protein/3,4-dihydroxyphenylacetaldehyde synthase | 分子名称: | 3,4-dihydroxyphenylacetaldehyde synthase | 著者 | Wei, S, Vavrick, C.J, Guan, H, Liao, C, Robinson, H, Liang, J, Wang, D, Han, Q, Li, J. | 登録日 | 2019-04-04 | 公開日 | 2019-04-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis for the bifunctional mechanism of Drosophila alpha methyldopa-resistant protein/3,4-dihydroxyphenylacetaldehyde synthase To Be Published
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5GVB
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![BU of 5gvb by Molmil](/molmil-images/mine/5gvb) | SepB domain of human AND-1 | 分子名称: | WD repeat and HMG-box DNA-binding protein 1 | 著者 | Guan, C.C, Li, J. | 登録日 | 2016-09-05 | 公開日 | 2017-04-19 | 最終更新日 | 2017-06-21 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | The structure and polymerase-recognition mechanism of the crucial adaptor protein AND-1 in the human replisome. J. Biol. Chem., 292, 2017
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3EXF
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![BU of 3exf by Molmil](/molmil-images/mine/3exf) | Crystal structure of the pyruvate dehydrogenase (E1p) component of human pyruvate dehydrogenase complex | 分子名称: | MAGNESIUM ION, POTASSIUM ION, Pyruvate dehydrogenase E1 component subunit alpha, ... | 著者 | Kato, M, Wynn, R.M, Chuang, J.L, Tso, S.-C, Machius, M, Li, J, Chuang, D.T. | 登録日 | 2008-10-16 | 公開日 | 2008-11-25 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.998 Å) | 主引用文献 | Structural basis for inactivation of the human pyruvate dehydrogenase complex by phosphorylation: role of disordered phosphorylation loops. Structure, 16, 2008
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3EXG
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![BU of 3exg by Molmil](/molmil-images/mine/3exg) | Crystal structure of the pyruvate dehydrogenase (E1p) component of human pyruvate dehydrogenase complex | 分子名称: | POTASSIUM ION, Pyruvate dehydrogenase E1 component subunit alpha, somatic form, ... | 著者 | Kato, M, Wynn, R.M, Chuang, J.L, Tso, S.-C, Machius, M, Li, J, Chuang, D.T. | 登録日 | 2008-10-16 | 公開日 | 2008-11-25 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.011 Å) | 主引用文献 | Structural basis for inactivation of the human pyruvate dehydrogenase complex by phosphorylation: role of disordered phosphorylation loops. Structure, 16, 2008
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4JFG
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![BU of 4jfg by Molmil](/molmil-images/mine/4jfg) | Crystal structure of sfGFP-66-HqAla | 分子名称: | CESIUM ION, Green fluorescent protein, quinolin-8-ol | 著者 | Wang, J, Liu, X, Li, J, Zhang, W, Hu, M, Zhou, J. | 登録日 | 2013-02-28 | 公開日 | 2013-10-02 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.001 Å) | 主引用文献 | Significant expansion of the fluorescent protein chromophore through the genetic incorporation of a metal-chelating unnatural amino acid. Angew.Chem.Int.Ed.Engl., 52, 2013
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3N2Y
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![BU of 3n2y by Molmil](/molmil-images/mine/3n2y) | |
2FA5
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![BU of 2fa5 by Molmil](/molmil-images/mine/2fa5) | The crystal structure of an unliganded multiple antibiotic-resistance repressor (MarR) from Xanthomonas campestris | 分子名称: | CHLORIDE ION, transcriptional regulator marR/emrR family | 著者 | Chin, K.H, Tu, Z.L, Li, J.N, Chou, C.C, Wang, A.H.J, Chou, S.H. | 登録日 | 2005-12-06 | 公開日 | 2006-11-14 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The crystal structure of XC1739: a putative multiple antibiotic-resistance repressor (MarR) from Xanthomonas campestris at 1.8 A resolution Proteins, 65, 2006
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4JCL
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![BU of 4jcl by Molmil](/molmil-images/mine/4jcl) | Crystal structure of Alpha-CGT from Paenibacillus macerans at 1.7 Angstrom resolution | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | 著者 | Wu, L, Zhou, J, Wu, J, Li, J, Chen, J. | 登録日 | 2013-02-22 | 公開日 | 2014-02-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal Structure of Alpha-Cgt from Paenibacillus Macerans at 1.7 Angstrom Resolution To be Published
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1W2X
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![BU of 1w2x by Molmil](/molmil-images/mine/1w2x) | Crystal structure of the carboxyltransferase domain of acetyl- coenzyme A carboxylase in complex with CP-640186 | 分子名称: | (3R)-1'-(9-ANTHRYLCARBONYL)-3-(MORPHOLIN-4-YLCARBONYL)-1,4'-BIPIPERIDINE, ACETYL-COA CARBOXYLASE | 著者 | Zhang, H, Tweel, B, Li, J, Tong, L. | 登録日 | 2004-07-09 | 公開日 | 2004-09-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structure of the Carboxyltransferase Domain of Acetyl-Coenzyme a Carboxylase in Complex with Cp-640186 Structure, 12, 2004
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7C82
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![BU of 7c82 by Molmil](/molmil-images/mine/7c82) | |
4GF6
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![BU of 4gf6 by Molmil](/molmil-images/mine/4gf6) | crystal structure of GFP with cuprum bound at the Incorporated metal Chelating Amino Acid PYZ151 | 分子名称: | CALCIUM ION, COPPER (II) ION, green fluorescent protein | 著者 | Dong, J, Liu, X, Li, J, Wang, J, Gong, W. | 登録日 | 2012-08-03 | 公開日 | 2012-08-29 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Genetic incorporation of a metal-chelating amino Acid as a probe for protein electron transfer. Angew.Chem.Int.Ed.Engl., 51, 2012
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4GES
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![BU of 4ges by Molmil](/molmil-images/mine/4ges) | crystal structure of GFP-TYR151PYZ with an unnatural amino acid incorporation | 分子名称: | Green fluorescent protein | 著者 | Dong, J, Liu, X, Li, J, Wang, J, Gong, W. | 登録日 | 2012-08-02 | 公開日 | 2012-08-29 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.23 Å) | 主引用文献 | Genetic incorporation of a metal-chelating amino Acid as a probe for protein electron transfer. Angew.Chem.Int.Ed.Engl., 51, 2012
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7VLN
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![BU of 7vln by Molmil](/molmil-images/mine/7vln) | NSD2-PWWP1 domain bound with an imidazol-5-yl benzonitrile compound | 分子名称: | 4-[5-[4-(aminomethyl)-2,6-dimethoxy-phenyl]-3-methyl-imidazol-4-yl]benzenecarbonitrile, Histone-lysine N-methyltransferase NSD2 | 著者 | Cao, D.Y, Li, Y.L, Li, J, Xiong, B. | 登録日 | 2021-10-05 | 公開日 | 2022-07-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | 主引用文献 | Structure-Based Discovery of a Series of NSD2-PWWP1 Inhibitors. J.Med.Chem., 65, 2022
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6AJH
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![BU of 6ajh by Molmil](/molmil-images/mine/6ajh) | Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with AU1235 | 分子名称: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, 1-(2-adamantyl)-3-[2,3,4-tris(fluoranyl)phenyl]urea, Drug exporters of the RND superfamily-like protein,Endolysin, ... | 著者 | Zhang, B, Li, J, Yang, X.L, Wu, L.J, Yang, H.T, Rao, Z.H. | 登録日 | 2018-08-27 | 公開日 | 2018-12-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.818 Å) | 主引用文献 | Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target. Cell, 176, 2019
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3EXI
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![BU of 3exi by Molmil](/molmil-images/mine/3exi) | Crystal structure of the pyruvate dehydrogenase (E1p) component of human pyruvate dehydrogenase complex with the subunit-binding domain (SBD) of E2p, but SBD cannot be modeled into the electron density | 分子名称: | CHLORIDE ION, POTASSIUM ION, Pyruvate dehydrogenase E1 component subunit alpha, ... | 著者 | Kato, M, Wynn, R.M, Chuang, J.L, Tso, S.-C, Machius, M, Li, J, Chuang, D.T. | 登録日 | 2008-10-16 | 公開日 | 2008-11-25 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis for inactivation of the human pyruvate dehydrogenase complex by phosphorylation: role of disordered phosphorylation loops. Structure, 16, 2008
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