6WEK
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![BU of 6wek by Molmil](/molmil-images/mine/6wek) | Structure of cGMP-bound WT TAX-4 reconstituted in lipid nanodiscs | 分子名称: | 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CYCLIC GUANOSINE MONOPHOSPHATE, ... | 著者 | Zheng, X, Fu, Z, Su, D, Zhang, Y, Li, M, Pan, Y, Li, H, Li, S, Grassucci, R.A, Ren, Z, Hu, Z, Li, X, Zhou, M, Li, G, Frank, J, Yang, J. | 登録日 | 2020-04-02 | 公開日 | 2020-06-03 | 最終更新日 | 2020-07-22 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Mechanism of ligand activation of a eukaryotic cyclic nucleotide-gated channel. Nat.Struct.Mol.Biol., 27, 2020
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6WEL
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![BU of 6wel by Molmil](/molmil-images/mine/6wel) | Structure of cGMP-unbound F403V/V407A mutant TAX-4 reconstituted in lipid nanodiscs | 分子名称: | 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cyclic nucleotide-gated cation channel, ... | 著者 | Zheng, X, Fu, Z, Su, D, Zhang, Y, Li, M, Pan, Y, Li, H, Li, S, Grassucci, R.A, Ren, Z, Hu, Z, Li, X, Zhou, M, Li, G, Frank, J, Yang, J. | 登録日 | 2020-04-02 | 公開日 | 2020-06-03 | 最終更新日 | 2020-07-22 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Mechanism of ligand activation of a eukaryotic cyclic nucleotide-gated channel. Nat.Struct.Mol.Biol., 27, 2020
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6WEJ
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![BU of 6wej by Molmil](/molmil-images/mine/6wej) | Structure of cGMP-unbound WT TAX-4 reconstituted in lipid nanodiscs | 分子名称: | 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cyclic nucleotide-gated cation channel, ... | 著者 | Zheng, X, Fu, Z, Su, D, Zhang, Y, Li, M, Pan, Y, Li, H, Li, S, Grassucci, R.A, Ren, Z, Hu, Z, Li, X, Zhou, M, Li, G, Frank, J, Yang, J. | 登録日 | 2020-04-02 | 公開日 | 2020-06-03 | 最終更新日 | 2020-07-22 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Mechanism of ligand activation of a eukaryotic cyclic nucleotide-gated channel. Nat.Struct.Mol.Biol., 27, 2020
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4RM0
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![BU of 4rm0 by Molmil](/molmil-images/mine/4rm0) | Crystal structure of Norovirus OIF P domain in complex with Lewis a trisaccharide | 分子名称: | Capsid protein, beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-alpha-D-glucopyranose, beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Liu, W, Chen, Y, Tan, M, Xia, M, Li, X, Jiang, X, Rao, Z. | 登録日 | 2014-10-18 | 公開日 | 2015-06-24 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.999 Å) | 主引用文献 | A Unique Human Norovirus Lineage with a Distinct HBGA Binding Interface. Plos Pathog., 11, 2015
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4RLZ
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![BU of 4rlz by Molmil](/molmil-images/mine/4rlz) | Crystal structure of Norovirus OIF P domain | 分子名称: | Capsid protein, GLYCEROL | 著者 | Liu, W, Chen, Y, Tan, M, Xia, M, Li, X, Jiang, X, Rao, Z. | 登録日 | 2014-10-18 | 公開日 | 2015-06-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | 主引用文献 | A Unique Human Norovirus Lineage with a Distinct HBGA Binding Interface. Plos Pathog., 11, 2015
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4UIS
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![BU of 4uis by Molmil](/molmil-images/mine/4uis) | The cryoEM structure of human gamma-Secretase complex | 分子名称: | GAMMA-SECRETASE, LYSOZYME | 著者 | Sun, L, Zhao, L, Yang, G, Yan, C, Zhou, R, Zhou, X, Xie, T, Zhao, Y, Wu, S, Li, X, Shi, Y. | 登録日 | 2015-04-03 | 公開日 | 2015-06-10 | 最終更新日 | 2017-08-02 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structural Basis of Human Gamma-Secretase Assembly. Proc.Natl.Acad.Sci.USA, 112, 2015
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6LH8
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![BU of 6lh8 by Molmil](/molmil-images/mine/6lh8) | Structure of aerolysin-like protein (Bombina maxima) | 分子名称: | aerolysin-like protein | 著者 | Bian, X.L, Wang, Q.Q, Li, X, Teng, M.Q, Zhang, Y. | 登録日 | 2019-12-07 | 公開日 | 2020-06-10 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.729 Å) | 主引用文献 | A cellular endolysosome-modulating pore-forming protein from a toad is negatively regulated by its paralog under oxidizing conditions. J.Biol.Chem., 295, 2020
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6LHZ
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![BU of 6lhz by Molmil](/molmil-images/mine/6lhz) | Structure of aerolysin-like protein (Bombina maxima) | 分子名称: | aerolysin-like protein | 著者 | Bian, X.L, Wang, Q.Q, Li, X, Teng, M.Q, Zhang, Y. | 登録日 | 2019-12-10 | 公開日 | 2020-06-10 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | A cellular endolysosome-modulating pore-forming protein from a toad is negatively regulated by its paralog under oxidizing conditions. J.Biol.Chem., 295, 2020
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5ADY
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![BU of 5ady by Molmil](/molmil-images/mine/5ady) | Cryo-EM structures of the 50S ribosome subunit bound with HflX | 分子名称: | 23S RRNA, 50S RIBOSOMAL PROTEIN L1, 50S RIBOSOMAL PROTEIN L10, ... | 著者 | Zhang, Y, Mandava, C.S, Cao, W, Li, X, Zhang, D, Li, N, Zhang, Y, Zhang, X, Qin, Y, Mi, K, Lei, J, Sanyal, S, Gao, N. | 登録日 | 2015-08-25 | 公開日 | 2015-10-14 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Hflx is a Ribosome Splitting Factor Rescuing Stalled Ribosomes Under Stress Conditions Nat.Struct.Mol.Biol., 22, 2015
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4I8B
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![BU of 4i8b by Molmil](/molmil-images/mine/4i8b) | Crystal Structure of Thioredoxin from Schistosoma Japonicum | 分子名称: | Thioredoxin | 著者 | Wu, Q, Peng, Y, Zhao, J, Li, X, Fan, X, Zhou, X, Chen, J, Luo, Z, Shi, D. | 登録日 | 2012-12-03 | 公開日 | 2013-12-04 | 最終更新日 | 2015-06-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Expression, characterization and crystal structure of thioredoxin from Schistosoma japonicum. Parasitology, 142, 2015
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3AQQ
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![BU of 3aqq by Molmil](/molmil-images/mine/3aqq) | Crystal structure of human CRHSP-24 | 分子名称: | Calcium-regulated heat stable protein 1 | 著者 | Hou, H, Wang, F, Zhang, W, Wang, D, Li, X, Bartlam, M, Yao, X, Rao, Z. | 登録日 | 2010-11-17 | 公開日 | 2010-12-22 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.798 Å) | 主引用文献 | CRHSP-24 is a novel cargo adaptor trafficking between stress granules and processing bodies To be Published
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8WYI
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![BU of 8wyi by Molmil](/molmil-images/mine/8wyi) | T cell receptor delta 2 gamma 9 with TCRD TM domain chimera of TRAC | 分子名称: | Signal peptide,flag tag,T cell receptor delta variable 2,T cell receptor delta constant,T cell receptor alpha chain constant,T cell receptor delta variable 2,T cell receptor delta constant,T cell receptor alpha chain constant, Signal peptide,flag tag,T cell receptor gamma variable 9,T cell receptor gamma constant 1,T cell receptor gamma variable 9,T cell receptor gamma constant 1, T-cell surface glycoprotein CD3 delta chain, ... | 著者 | Xin, W, Huang, B, Chi, X, Liu, Y, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q. | 登録日 | 2023-10-31 | 公開日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structures of human gamma delta T cell receptor-CD3 complex. Nature, 2024
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8WY0
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![BU of 8wy0 by Molmil](/molmil-images/mine/8wy0) | T cell receptor delta 2 gamma 9 with F283A, F290A, and F291A | 分子名称: | CHOLESTEROL, Signal peptide,flag tag,T cell receptor delta variable 2,T cell receptor delta constant, Signal peptide,flag tag,T cell receptor gamma variable 9,T cell receptor gamma constant 1, ... | 著者 | Xin, W, Huang, B, Chi, X, Liu, Y, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q. | 登録日 | 2023-10-30 | 公開日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structures of human gamma delta T cell receptor-CD3 complex. Nature, 2024
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8YC0
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![BU of 8yc0 by Molmil](/molmil-images/mine/8yc0) | T cell receptor V delta2 V gamma9 in GDN | 分子名称: | CHOLESTEROL, T cell receptor delta variable 2,T cell receptor delta constant, T cell receptor gamma variable 9,T cell receptor gamma constant 1, ... | 著者 | Xin, W, Huang, B, Chi, X, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q. | 登録日 | 2024-02-17 | 公開日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (4.12 Å) | 主引用文献 | Structures of human gamma delta T cell receptor-CD3 complex. Nature, 2024
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8WXE
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![BU of 8wxe by Molmil](/molmil-images/mine/8wxe) | Vgamma5Vdelta1 EH TCR-CD3 complex | 分子名称: | CHOLESTEROL, Signal peptide,flag tag,T cell receptor delta variable 1,T cell receptor delta constant, Signal peptide,flag tag,T cell receptor gamma variable 5,T cell receptor gamma constant 1, ... | 著者 | Xin, W, Huang, B, Chi, X, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q. | 登録日 | 2023-10-28 | 公開日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structures of human gamma delta T cell receptor-CD3 complex. Nature, 2024
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7BW7
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![BU of 7bw7 by Molmil](/molmil-images/mine/7bw7) | Cryo-EM Structure for the Ectodomain of the Full-length Human Insulin Receptor in Complex with 1 Insulin. | 分子名称: | Insulin fusion, Insulin receptor | 著者 | Yu, D, Zhang, X, Sun, J, Li, X, Wu, Z, Han, X, Fan, C, Ma, Y, Ouyang, Q, Wang, T. | 登録日 | 2020-04-13 | 公開日 | 2021-04-14 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Insulin Binding Induced the Ectodomain Conformational Dynamics in the Full-length Human Insulin Receptor To Be Published
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5LME
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![BU of 5lme by Molmil](/molmil-images/mine/5lme) | Specific-DNA binding activity of the cross-brace zinc finger motif of the piggyBac transposase | 分子名称: | ZINC ION, piggyBac transposase | 著者 | Morellet, N, Taylor, J.A, Wieninger, S, Moriau, S, Li, X, Lescop, E, Mathy, N, Bischerour, J, Betermier, M, Bardiaux, B, Nilges, M, Craig, N.L, Hickman, A.B, Dyda, F, Guittet, E. | 登録日 | 2016-07-30 | 公開日 | 2017-12-20 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Sequence-specific DNA binding activity of the cross-brace zinc finger motif of the piggyBac transposase. Nucleic Acids Res., 46, 2018
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3VBH
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![BU of 3vbh by Molmil](/molmil-images/mine/3vbh) | Crystal structure of formaldehyde treated human enterovirus 71 (space group R32) | 分子名称: | CHLORIDE ION, Genome Polyprotein, capsid protein VP1, ... | 著者 | Wang, X, Peng, W, Ren, J, Hu, Z, Xu, J, Lou, Z, Li, X, Yin, W, Shen, X, Porta, C, Walter, T.S, Evans, G, Axford, D, Owen, R, Rowlands, D.J, Wang, J, Stuart, D.I, Fry, E.E, Rao, Z. | 登録日 | 2012-01-02 | 公開日 | 2012-02-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71. Nat.Struct.Mol.Biol., 19, 2012
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3VBR
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![BU of 3vbr by Molmil](/molmil-images/mine/3vbr) | Crystal structure of formaldehyde treated empty human Enterovirus 71 particle (room temperature) | 分子名称: | Genome Polyprotein, capsid protein VP0, capsid protein VP1, ... | 著者 | Wang, X, Peng, W, Ren, J, Hu, Z, Xu, J, Lou, Z, Li, X, Yin, W, Shen, X, Porta, C, Walter, T.S, Evans, G, Axford, D, Owen, R, Rowlands, D.J, Wang, J, Stuart, D.I, Fry, E.E, Rao, Z. | 登録日 | 2012-01-02 | 公開日 | 2012-02-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71. Nat.Struct.Mol.Biol., 19, 2012
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3VBF
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![BU of 3vbf by Molmil](/molmil-images/mine/3vbf) | Crystal structure of formaldehyde treated human Enterovirus 71 (space group I23) | 分子名称: | ADENOSINE MONOPHOSPHATE, CHLORIDE ION, Genome Polyprotein, ... | 著者 | Wang, X, Peng, W, Ren, J, Hu, Z, Xu, J, Lou, Z, Li, X, Yin, W, Shen, X, Porta, C, Walter, T.S, Evans, G, Axford, D, Owen, R, Rowlands, D.J, Wang, J, Stuart, D.I, Fry, E.E, Rao, Z. | 登録日 | 2012-01-02 | 公開日 | 2012-02-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71. Nat.Struct.Mol.Biol., 19, 2012
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6LML
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![BU of 6lml by Molmil](/molmil-images/mine/6lml) | Cryo-EM structure of the human glucagon receptor in complex with Gi1 | 分子名称: | Glucagon, Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Qiao, A, Han, S, Li, X, Sun, F, Zhao, Q, Wu, B. | 登録日 | 2019-12-26 | 公開日 | 2020-04-01 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural basis of Gsand Girecognition by the human glucagon receptor. Science, 367, 2020
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3VBO
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![BU of 3vbo by Molmil](/molmil-images/mine/3vbo) | Crystal structure of formaldehyde treated empty human Enterovirus 71 particle (cryo at 100K) | 分子名称: | Genome Polyprotein, capsid protein VP1, capsid protein VP2, ... | 著者 | Wang, X, Peng, W, Ren, J, Hu, Z, Xu, J, Lou, Z, Li, X, Yin, W, Shen, X, Porta, C, Walter, T.S, Evans, G, Axford, D, Owen, R, Rowlands, D.J, Wang, J, Stuart, D.I, Fry, E.E, Rao, Z. | 登録日 | 2012-01-02 | 公開日 | 2012-02-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | 主引用文献 | A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71. Nat.Struct.Mol.Biol., 19, 2012
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5KZN
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![BU of 5kzn by Molmil](/molmil-images/mine/5kzn) | Metabotropic Glutamate Receptor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, Metabotropic glutamate receptor 2 | 著者 | Chappell, M.D, Li, R, Smith, S.C, Dressman, B.A, Tromiczak, E.G, Tripp, A.E, Blanco, M.-J, Vetman, T, Quimby, S.J, Matt, J, Britton, T, Fivush, A.M, Schkeryantz, J.M, Mayhugh, D, Erickson, J.A, Bures, M, Jaramillo, C, Carpintero, M, de Diego, J.E, Barberis, M, Garcia-Cerrada, S, Soriano, J.F, Antonysamy, S, Atwell, S, MacEwan, I, Condon, B, Bradley, C, Wang, J, Zhang, A, Conners, K, Groshong, C, Wasserman, S.R, Koss, J.W, Witkin, J.M, Li, X, Overshiner, C, Wafford, K.A, Seidel, W, Wang, X.-S, Heinz, B.A, Swanson, S, Catlow, J, Bedwell, D, Monn, J.A, Mitch, C.H, Ornstein, P. | 登録日 | 2016-07-25 | 公開日 | 2016-12-28 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Discovery of (1S,2R,3S,4S,5R,6R)-2-Amino-3-[(3,4-difluorophenyl)sulfanylmethyl]-4-hydroxy-bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid Hydrochloride (LY3020371HCl): A Potent, Metabotropic Glutamate 2/3 Receptor Antagonist with Antidepressant-Like Activity. J. Med. Chem., 59, 2016
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5KZQ
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![BU of 5kzq by Molmil](/molmil-images/mine/5kzq) | Metabotropic Glutamate Receptor in complex with antagonist (1~{S},2~{R},3~{S},4~{S},5~{R},6~{R})-2-azanyl-3-[[3,4-bis(fluoranyl)phenyl]sulfanylmethyl]-4-oxidanyl-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid | 分子名称: | (1~{S},2~{R},3~{S},4~{S},5~{R},6~{R})-2-azanyl-3-[[3,4-bis(fluoranyl)phenyl]sulfanylmethyl]-4-oxidanyl-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 2 | 著者 | Chappell, M.D, Li, R, Smith, S.C, Dressman, B.A, Tromiczak, E.G, Tripp, A.E, Blanco, M.-J, Vetman, T, Quimby, S.J, Matt, J, Britton, T, Fivush, A.M, Schkeryantz, J.M, Mayhugh, D, Erickson, J.A, Bures, M, Jaramillo, C, Carpintero, M, de Diego, J.E, Barberis, M, Garcia-Cerrada, S, Soriano, J.F, Antonysamy, S, Atwell, S, MacEwan, I, Condon, B, Bradley, C, Wang, J, Zhang, A, Conners, K, Groshong, C, Wasserman, S.R, Koss, J.W, Witkin, J.M, Li, X, Overshiner, C, Wafford, K.A, Seidel, W, Wang, X.-S, Heinz, B.A, Swanson, S, Catlow, J, Bedwell, D, Monn, J.A, Mitch, C.H, Ornstein, P. | 登録日 | 2016-07-25 | 公開日 | 2016-12-28 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Discovery of (1S,2R,3S,4S,5R,6R)-2-Amino-3-[(3,4-difluorophenyl)sulfanylmethyl]-4-hydroxy-bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid Hydrochloride (LY3020371HCl): A Potent, Metabotropic Glutamate 2/3 Receptor Antagonist with Antidepressant-Like Activity. J. Med. Chem., 59, 2016
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3VBS
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![BU of 3vbs by Molmil](/molmil-images/mine/3vbs) | Crystal structure of human Enterovirus 71 | 分子名称: | Genome Polyprotein, capsid protein VP1, capsid protein VP2, ... | 著者 | Wang, X, Peng, W, Ren, J, Hu, Z, Xu, J, Lou, Z, Li, X, Yin, W, Shen, X, Porta, C, Walter, T.S, Evans, G, Axford, D, Owen, R, Rowlands, D.J, Wang, J, Stuart, D.I, Fry, E.E, Rao, Z. | 登録日 | 2012-01-02 | 公開日 | 2012-02-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71. Nat.Struct.Mol.Biol., 19, 2012
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