8DJK

HMGCR-UBIAD1 Complex State 2

Summary for 8DJK

• Entry DOI: 10.2210/pdb8djk/pdb
• EMDB information: 27460
• Descriptor: 3-hydroxy-3-methylglutaryl-coenzyme A reductase, UbiA prenyltransferase domain-containing protein 1, Soluble cytochrome b562, ... (7 entities in total)
• Functional Keywords: cholesterol, membrane protein, oxidoreductase-immune system complex, oxidoreductase/immune system
• Biological source: Cricetulus griseus (Chinese hamster); More
• Total number of polymer chains: 5
• Total formula weight: 141394.51

Authors

Chen, H.,Qi, X.,Li, X. (deposition date: 2022-06-30, release date: 2022-08-03)

• Primary citation: Chen, H.,Qi, X.,Faulkner, R.A.,Schumacher, M.M.,Donnelly, L.M.,DeBose-Boyd, R.A.,Li, X.; Regulated degradation of HMG CoA reductase requires conformational changes in sterol-sensing domain.; Nat Commun, 13:4273-4273, 2022; PubMed: 35879350; DOI: 10.1038/s41467-022-32025-5

Experimental method

ELECTRON MICROSCOPY (3.33 Å)