8JYC

Crystal Structure of Intracellular B30.2 Domain of BTN3A1 and BTN2A1 in Complex with DMAPP

Summary for 8JYC

Entry DOI	10.2210/pdb8jyc/pdb
Descriptor	Butyrophilin subfamily 2 member A1, Butyrophilin subfamily 3 member A1, 1,2-ETHANEDIOL, ... (9 entities in total)
Functional Keywords	butyrophilin, signaling protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	97670.36
Authors	Yuan, L.J.,Yang, Y.Y.,Li, X.,Cai, N.N.,Chen, C.-C.,Guo, R.-T.,Zhang, Y.H. (deposition date: 2023-07-03, release date: 2023-09-13, Last modification date: 2023-10-18)
Primary citation	Yuan, L.,Ma, X.,Yang, Y.,Qu, Y.,Li, X.,Zhu, X.,Ma, W.,Duan, J.,Xue, J.,Yang, H.,Huang, J.W.,Yi, S.,Zhang, M.,Cai, N.,Zhang, L.,Ding, Q.,Lai, K.,Liu, C.,Zhang, L.,Liu, X.,Yao, Y.,Zhou, S.,Li, X.,Shen, P.,Chang, Q.,Malwal, S.R.,He, Y.,Li, W.,Chen, C.,Chen, C.C.,Oldfield, E.,Guo, R.T.,Zhang, Y. Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells. Nature, 621:840-848, 2023 Cited by PubMed: 37674084 DOI: 10.1038/s41586-023-06525-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.29 Å)

Structure validation