8JYC

Crystal Structure of Intracellular B30.2 Domain of BTN3A1 and BTN2A1 in Complex with DMAPP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Butyrophilin subfamily 2 member A1	polymer	218	24676.9	2	UniProt (Q7KYR7) Pfam (PF13765) Pfam (PF00622)	Homo sapiens (human)
2	C, D (C, D)	Butyrophilin subfamily 3 member A1	polymer	196	22661.8	2	UniProt (O00481) Pfam (PF13765) Pfam (PF00622)	Homo sapiens (human)
3	E, L, O, P, Q... (A, B, C)	1,2-ETHANEDIOL	non-polymer		62.1	8	Chemie (EDO)
4	F, G, H, V (A, C)	PENTAETHYLENE GLYCOL	non-polymer		238.3	4	Chemie (1PE)
5	I, J, W (A, C)	TETRAETHYLENE GLYCOL	non-polymer		194.2	3	Chemie (PG4)
6	K (A)	TRIETHYLENE GLYCOL	non-polymer		150.2	1	Chemie (PGE)
7	M, N, S (B)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	3	Chemie (PEG)
8	T, Y (C, D)	DIMETHYLALLYL DIPHOSPHATE	non-polymer		246.1	2	Chemie (DMA)
9	AA, BA, CA, Z (B, C, D, A)	water	water		18.0	330	Chemie (HOH)

Sequence modifications

A, B: 316 - 527 (UniProt: Q7KYR7)

PDB	External Database	Details
Gly 310	-	expression tag
Ala 311	-	expression tag
Gly 312	-	expression tag
Ala 313	-	expression tag
Gly 314	-	expression tag
Ala 315	-	expression tag

C, D: 298 - 483 (UniProt: O00481)

PDB	External Database	Details
Met 296	-	expression tag
Gly 297	-	expression tag
Leu 484	-	expression tag
Glu 485	-	expression tag
His 486	-	expression tag
His 487	-	expression tag
His 488	-	expression tag
His 489	-	expression tag
His 490	-	expression tag
His 491	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	94677.3
Non-Polymers*	Number of molecules	21
	Total formula weight	2993.1
All*	Total formula weight	97670.4

*Water molecules are not included.