5TJC
I-II linker of TRPML1 channel at pH 7.5
Summary for 5TJC
Entry DOI | 10.2210/pdb5tjc/pdb |
Related | 5TJA 5TJB |
Descriptor | Mucolipin-1 (2 entities in total) |
Functional Keywords | endolysosomal lumen, tetramer, calcium and ph regulation, transport protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 25195.06 |
Authors | Li, M.,Zhang, W.K.,Benvin, N.M.,Zhou, X.,Su, D.,Li, H.,Wang, S.,Michailidis, I.E.,Tong, L.,Li, X.,Yang, J. (deposition date: 2016-10-04, release date: 2017-01-25, Last modification date: 2023-10-04) |
Primary citation | Li, M.,Zhang, W.K.,Benvin, N.M.,Zhou, X.,Su, D.,Li, H.,Wang, S.,Michailidis, I.E.,Tong, L.,Li, X.,Yang, J. Structural basis of dual Ca(2+)/pH regulation of the endolysosomal TRPML1 channel. Nat. Struct. Mol. Biol., 24:205-213, 2017 Cited by PubMed: 28112729DOI: 10.1038/nsmb.3362 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
Download full validation report