4JFG
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![BU of 4jfg by Molmil](/molmil-images/mine/4jfg) | Crystal structure of sfGFP-66-HqAla | Descriptor: | CESIUM ION, Green fluorescent protein, quinolin-8-ol | Authors: | Wang, J, Liu, X, Li, J, Zhang, W, Hu, M, Zhou, J. | Deposit date: | 2013-02-28 | Release date: | 2013-10-02 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.001 Å) | Cite: | Significant expansion of the fluorescent protein chromophore through the genetic incorporation of a metal-chelating unnatural amino acid. Angew.Chem.Int.Ed.Engl., 52, 2013
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3PD6
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![BU of 3pd6 by Molmil](/molmil-images/mine/3pd6) | Crystal structure of mouse mitochondrial aspartate aminotransferase, a newly identified kynurenine aminotransferase-IV | Descriptor: | (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Aspartate aminotransferase, ... | Authors: | Han, Q, Robinson, H, Cai, T, Tagle, D.A, Li, J. | Deposit date: | 2010-10-22 | Release date: | 2010-11-10 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Biochemical and structural characterization of mouse mitochondrial aspartate aminotransferase, a newly identified kynurenine aminotransferase-IV. Biosci.Rep., 31, 2011
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3PDB
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![BU of 3pdb by Molmil](/molmil-images/mine/3pdb) | Crystal structure of mouse mitochondrial aspartate aminotransferase in complex with oxaloacetic acid | Descriptor: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Aspartate aminotransferase, mitochondrial, ... | Authors: | Han, Q, Robinson, H, Cai, T, Tagle, D.A, Li, J. | Deposit date: | 2010-10-22 | Release date: | 2010-11-10 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Biochemical and structural characterization of mouse mitochondrial aspartate aminotransferase, a newly identified kynurenine aminotransferase-IV. Biosci.Rep., 31, 2011
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6LAN
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![BU of 6lan by Molmil](/molmil-images/mine/6lan) | Structure of CCDC50 and LC3B complex | Descriptor: | Coiled-coil domain-containing protein 50,Microtubule-associated proteins 1A/1B light chain 3B | Authors: | Liu, L, Li, J, Hou, P. | Deposit date: | 2019-11-12 | Release date: | 2020-09-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.41 Å) | Cite: | A novel selective autophagy receptor, CCDC50, delivers K63 polyubiquitination-activated RIG-I/MDA5 for degradation during viral infection. Cell Res., 31, 2021
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4JCL
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![BU of 4jcl by Molmil](/molmil-images/mine/4jcl) | Crystal structure of Alpha-CGT from Paenibacillus macerans at 1.7 Angstrom resolution | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | Authors: | Wu, L, Zhou, J, Wu, J, Li, J, Chen, J. | Deposit date: | 2013-02-22 | Release date: | 2014-02-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of Alpha-Cgt from Paenibacillus Macerans at 1.7 Angstrom Resolution To be Published
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7YF7
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![BU of 7yf7 by Molmil](/molmil-images/mine/7yf7) | |
7DL2
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![BU of 7dl2 by Molmil](/molmil-images/mine/7dl2) | Cryo-EM structure of human TSC complex | Descriptor: | Hamartin, Isoform 7 of Tuberin, TBC1 domain family member 7, ... | Authors: | Yang, H, Yu, Z, Chen, X, Li, J, Li, N, Cheng, J, Gao, N, Yuan, H, Ye, D, Guan, K, Xu, Y. | Deposit date: | 2020-11-25 | Release date: | 2020-12-16 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Structural insights into TSC complex assembly and GAP activity on Rheb. Nat Commun, 12, 2021
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3UC3
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![BU of 3uc3 by Molmil](/molmil-images/mine/3uc3) | The crystal structure of Snf1-related kinase 2.3 | Descriptor: | COBALT (II) ION, Serine/threonine-protein kinase SRK2I | Authors: | Zhou, X.E, Ng, L.-M, Soon, F.-F, Kovach, A, Suino-Powell, K.M, Li, J, Melcher, K, Xu, H.E. | Deposit date: | 2011-10-25 | Release date: | 2011-12-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for basal activity and autoactivation of abscisic acid (ABA) signaling SnRK2 kinases. Proc.Natl.Acad.Sci.USA, 108, 2011
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8YKW
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![BU of 8ykw by Molmil](/molmil-images/mine/8ykw) | Cryo-EM structure of succinate receptor SUCR1 bound to succinic acid | Descriptor: | Antibody fragment ScFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Li, C, Liu, H, Li, J, Zhu, H, Fu, W, Xu, H.E. | Deposit date: | 2024-03-05 | Release date: | 2024-05-29 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.75 Å) | Cite: | Molecular basis of ligand recognition and activation of the human succinate receptor SUCR1. Cell Res., 2024
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8YKV
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![BU of 8ykv by Molmil](/molmil-images/mine/8ykv) | Cryo-EM structure of succinate receptor SUCR1 bound to compound 31 | Descriptor: | (2~{S})-2-[[6-[4-(trifluoromethyloxy)phenyl]pyridin-2-yl]carbonylamino]butanedioic acid, Antibody fragment ScFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Li, C, Liu, H, Li, J, Zhu, H, Fu, W, Xu, H.E. | Deposit date: | 2024-03-05 | Release date: | 2024-05-29 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.48 Å) | Cite: | Molecular basis of ligand recognition and activation of the human succinate receptor SUCR1. Cell Res., 2024
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8YKX
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![BU of 8ykx by Molmil](/molmil-images/mine/8ykx) | Cryo-EM structure of succinate receptor SUCR1 bound to maleic acid | Descriptor: | Antibody fragment ScFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Li, C, Liu, H, Li, J, Zhu, H, Fu, W, Xu, H.E. | Deposit date: | 2024-03-05 | Release date: | 2024-05-29 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.69 Å) | Cite: | Molecular basis of ligand recognition and activation of the human succinate receptor SUCR1. Cell Res., 2024
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6LKA
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![BU of 6lka by Molmil](/molmil-images/mine/6lka) | Crystal Structure of EV71-3C protease with a Novel Macrocyclic Compounds | Descriptor: | 3C proteinase, ~{N}-[(2~{S})-1-[[(2~{S},3~{S},6~{S},7~{Z},12~{E})-4,9-bis(oxidanylidene)-6-[[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]methyl]-2-phenyl-1,10-dioxa-5-azacyclopentadeca-7,12-dien-3-yl]amino]-3-methyl-1-oxidanylidene-butan-2-yl]-5-methyl-1,2-oxazole-3-carboxamide | Authors: | Li, P, Wu, S.Q, Xiao, T.Y.C, Li, Y.L, Su, Z.M, Hao, F, Hu, G.P, Hu, J, Lin, F.S, Chen, X.S, Gu, Z.X, He, H.Y, Li, J, Chen, S.H. | Deposit date: | 2019-12-18 | Release date: | 2020-06-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.033 Å) | Cite: | Design, synthesis, and evaluation of a novel macrocyclic anti-EV71 agent. Bioorg.Med.Chem., 28, 2020
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7YL2
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![BU of 7yl2 by Molmil](/molmil-images/mine/7yl2) | Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor Y07004 | Descriptor: | Bromodomain-containing protein 4, GLYCEROL, N-(1-ethyl-2-oxidanylidene-3H-indol-5-yl)cyclohexanesulfonamide, ... | Authors: | Huang, Y, Wei, A, Dong, R, Xu, H, Zhang, C, Chen, Z, Li, J, Wu, X, Zhang, Y, Xu, Y. | Deposit date: | 2022-07-25 | Release date: | 2023-07-26 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor Y07004 To Be Published
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8ZMO
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![BU of 8zmo by Molmil](/molmil-images/mine/8zmo) | Structure of a triple-helix region of human Collagen type XVII from Trautec | Descriptor: | collagen type XVII | Authors: | Chu, Y, Zhai, Y, Fan, X, Fu, S, Li, J, Wu, X, Cai, H, Wang, X, Li, D, Feng, P, Cao, K, Qian, S. | Deposit date: | 2024-05-23 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure of a triple-helix region of human Collagen type XVII from Trautec To Be Published
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1OLX
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![BU of 1olx by Molmil](/molmil-images/mine/1olx) | Roles of His291-alpha and His146-beta' in the reductive acylation reaction catalyzed by human branched-chain alpha-ketoacid dehydrogenase | Descriptor: | 2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, GLYCEROL, ... | Authors: | Wynn, R.M, Machius, M, Chuang, J.L, Li, J, Tomchick, D.R, Chuang, D.T. | Deposit date: | 2003-08-18 | Release date: | 2003-08-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Roles of His291-Alpha and His146-Beta' in the Reductive Acylation Reaction Catalyzed by Human Branched-Chain Alpha-Ketoacid Dehydrogenase: Refined Phosphorylation Loop Structure in the Active Site. J.Biol.Chem., 278, 2003
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8ZMM
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![BU of 8zmm by Molmil](/molmil-images/mine/8zmm) | Structure of a triple-helix region of human Collagen type IV from Trautec | Descriptor: | collagen type IV | Authors: | Chu, Y, Zhai, Y, Fan, X, Fu, S, Li, J, Wu, X, Cai, H, Wang, X, Li, D, Feng, P, Cao, K, Qian, S. | Deposit date: | 2024-05-23 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structure of a triple-helix region of human Collagen type IV from Trautec To Be Published
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8ZMW
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![BU of 8zmw by Molmil](/molmil-images/mine/8zmw) | Structure of a triple-helix region of human Collagen type VII from Trautec | Descriptor: | ACETATE ION, collagen type VII | Authors: | Chu, Y, Zhai, Y, Fan, X, Fu, S, Li, J, Wu, X, Cai, H, Wang, X, Li, D, Feng, P, Cao, K, Qian, S. | Deposit date: | 2024-05-24 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure of a triple-helix region of human Collagen type VII from Trautec To Be Published
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4LJY
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![BU of 4ljy by Molmil](/molmil-images/mine/4ljy) | Crystal structure of RNA splicing effector Prp5 in complex with ADP | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Zhang, Z.-M, Li, J, Yang, F, Xu, Y, Zhou, J. | Deposit date: | 2013-07-05 | Release date: | 2013-12-11 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of Prp5p reveals interdomain interactions that impact spliceosome assembly. Cell Rep, 5, 2013
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4LAD
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![BU of 4lad by Molmil](/molmil-images/mine/4lad) | Crystal Structure of the Ube2g2:RING-G2BR complex | Descriptor: | E3 ubiquitin-protein ligase AMFR, OXALATE ION, Ubiquitin-conjugating enzyme E2 G2, ... | Authors: | Liang, Y.-H, Li, J, Das, R, Byrd, R.A, Ji, X. | Deposit date: | 2013-06-19 | Release date: | 2013-08-28 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine. Embo J., 32, 2013
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8ZMV
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![BU of 8zmv by Molmil](/molmil-images/mine/8zmv) | Structure of a triple-helix region of human Collagen type XVII from Trautec | Descriptor: | collagen type XVII | Authors: | Chu, Y, Zhai, Y, Fan, X, Fu, S, Li, J, Wu, X, Cai, H, Wang, X, Li, D, Feng, P, Cao, K, Qian, S. | Deposit date: | 2024-05-24 | Release date: | 2024-07-31 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure of a triple-helix region of human Collagen type XVII from Trautec To Be Published
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4LK2
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![BU of 4lk2 by Molmil](/molmil-images/mine/4lk2) | Crystal structure of RNA splicing effector Prp5 | Descriptor: | NICKEL (II) ION, Pre-mRNA-processing ATP-dependent RNA helicase PRP5 | Authors: | Zhang, Z.-M, Li, J, Yang, F, Xu, Y, Zhou, J. | Deposit date: | 2013-07-05 | Release date: | 2013-12-11 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | Crystal structure of Prp5p reveals interdomain interactions that impact spliceosome assembly. Cell Rep, 5, 2013
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1SZJ
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![BU of 1szj by Molmil](/molmil-images/mine/1szj) | |
3PDX
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![BU of 3pdx by Molmil](/molmil-images/mine/3pdx) | Crystal structural of mouse tyrosine aminotransferase | Descriptor: | Tyrosine aminotransferase | Authors: | Mehere, P.V, Han, Q, Lemkul, J.A, Robinson, H, Bevan, D.R, Li, J. | Deposit date: | 2010-10-25 | Release date: | 2010-11-03 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | Tyrosine aminotransferase: biochemical and structural properties and molecular dynamics simulations. Protein Cell, 1, 2010
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6IZQ
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![BU of 6izq by Molmil](/molmil-images/mine/6izq) | PRMT4 bound with a bicyclic compound | Descriptor: | (2R)-1-(methylamino)-3-(1,3,4,5-tetrahydro-2-benzazepin-2-yl)propan-2-ol, Histone-arginine methyltransferase CARM1 | Authors: | Xiong, B, Cao, D.Y, Guo, Z.H, Li, Y.L, Li, J, Huang, X, Shen, J.K. | Deposit date: | 2018-12-20 | Release date: | 2019-12-25 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.449 Å) | Cite: | Design and Synthesis of Potent, Selective Inhibitors of Protein Arginine Methyltransferase 4 against Acute Myeloid Leukemia. J.Med.Chem., 62, 2019
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1OLU
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![BU of 1olu by Molmil](/molmil-images/mine/1olu) | Roles of His291-alpha and His146-beta' in the reductive acylation reaction catalyzed by human branched-chain alpha-ketoacid dehydrogenase | Descriptor: | 2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, GLYCEROL, ... | Authors: | Wynn, R.M, Machius, M, Chuang, J.L, Li, J, Tomchick, D.R, Chuang, D.T. | Deposit date: | 2003-08-15 | Release date: | 2003-08-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Roles of His291-Alpha and His146-Beta' in the Reductive Acylation Reaction Catalyzed by Human Branched-Chain Alpha-Ketoacid Dehydrogenase: Refined Phosphorylation Loop Structure in the Active Site. J.Biol.Chem., 278, 2003
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