2AG9
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![BU of 2ag9 by Molmil](/molmil-images/mine/2ag9) | Crystal Structure of the Y137S mutant of GM2-Activator Protein | Descriptor: | Ganglioside GM2 activator, ISOPROPYL ALCOHOL, MYRISTIC ACID | Authors: | Wright, C.S, Mi, L.Z, Lee, S, Rastinejad, F. | Deposit date: | 2005-07-26 | Release date: | 2005-10-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity. Biochemistry, 44, 2005
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2AGC
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![BU of 2agc by Molmil](/molmil-images/mine/2agc) | Crystal Structure of mouse GM2- activator Protein | Descriptor: | Ganglioside GM2 activator, LAURIC ACID, MYRISTIC ACID | Authors: | Wright, C.S, Mi, L.Z, Lee, S, Rastinejad, F. | Deposit date: | 2005-07-26 | Release date: | 2005-10-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity. Biochemistry, 44, 2005
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2F6M
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![BU of 2f6m by Molmil](/molmil-images/mine/2f6m) | Structure of a Vps23-C:Vps28-N subcomplex | Descriptor: | DECYLAMINE-N,N-DIMETHYL-N-OXIDE, MAGNESIUM ION, Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease, ... | Authors: | Kostelansky, M.S, Lee, S, Kim, J, Hurley, J.H. | Deposit date: | 2005-11-29 | Release date: | 2006-04-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and functional organization of the ESCRT-I trafficking complex. Cell(Cambridge,Mass.), 125, 2006
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2AF9
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![BU of 2af9 by Molmil](/molmil-images/mine/2af9) | Crystal Structure analysis of GM2-Activator protein complexed with phosphatidylcholine | Descriptor: | Ganglioside GM2 activator, ISOPROPYL ALCOHOL, LAURIC ACID, ... | Authors: | Wright, C.S, Mi, L.Z, Lee, S, Rastinejad, F. | Deposit date: | 2005-07-25 | Release date: | 2005-10-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity. Biochemistry, 44, 2005
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1YD8
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![BU of 1yd8 by Molmil](/molmil-images/mine/1yd8) | COMPLEX OF HUMAN GGA3 GAT DOMAIN AND UBIQUITIN | Descriptor: | ADP-RIBOSYLATION FACTOR BINDING PROTEIN GGA3, UBIQUIN | Authors: | Prag, G, Lee, S, Mattera, R, Arighi, C.N, Beach, B.M, Bonifacino, J.S, Hurley, J.H. | Deposit date: | 2004-12-23 | Release date: | 2005-02-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural mechanism for ubiquitinated-cargo recognition by the Golgi-localized, {gamma}-ear-containing, ADP-ribosylation-factor-binding proteins Proc.Natl.Acad.Sci.USA, 102, 2005
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2AG2
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![BU of 2ag2 by Molmil](/molmil-images/mine/2ag2) | Crystal Structure Analysis of GM2-activator protein complexed with Phosphatidylcholine | Descriptor: | (7R)-4,7-DIHYDROXY-N,N,N-TRIMETHYL-10-OXO-3,5,9-TRIOXA-4-PHOSPHAHEPTACOSAN-1-AMINIUM 4-OXIDE, 2-(((R)-2,3-DIHYDROXYPROPYL)PHOSPHORYLOXY)-N,N,N-TRIMETHYLETHANAMINIUM, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Wright, C.S, Mi, L.Z, Lee, S, Rastinejad, F. | Deposit date: | 2005-07-26 | Release date: | 2005-10-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity. Biochemistry, 44, 2005
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2F66
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![BU of 2f66 by Molmil](/molmil-images/mine/2f66) | Structure of the ESCRT-I endosomal trafficking complex | Descriptor: | Protein SRN2, SULFATE ION, Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease, ... | Authors: | Kostelansky, M.S, Lee, S, Kim, J, Hurley, J.H. | Deposit date: | 2005-11-28 | Release date: | 2006-04-18 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural and functional organization of the ESCRT-I trafficking complex. Cell(Cambridge,Mass.), 125, 2006
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3NYJ
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![BU of 3nyj by Molmil](/molmil-images/mine/3nyj) | Crystal Structure Analysis of APP E2 domain | Descriptor: | Amyloid beta A4 protein, OSMIUM ION | Authors: | Ha, Y, Hu, J, Lee, S, Liu, X. | Deposit date: | 2010-07-15 | Release date: | 2011-06-01 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The E2 Domains of APP and APLP1 Share a Conserved Mode of Dimerization. Biochemistry, 50, 2011
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5EOZ
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![BU of 5eoz by Molmil](/molmil-images/mine/5eoz) | Mutagenicity of 7-Benzyl guanine lesion and Replication by Human DNA Polymerase beta | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*CP*GP*AP*CP*(GFL)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... | Authors: | Koag, M.C, Lee, S. | Deposit date: | 2015-11-10 | Release date: | 2016-11-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.088 Å) | Cite: | Structural and kinetic studies of the effect of guanine-N7 alkylation and metal cofactors on DNA replication. Biochemistry, 2018
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5EDW
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![BU of 5edw by Molmil](/molmil-images/mine/5edw) | |
5HHH
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![BU of 5hhh by Molmil](/molmil-images/mine/5hhh) | Structure of human DNA polymerase beta Host-Guest complexed with the control G for N7-CBZ-platination | Descriptor: | DNA (5'-D(*CP*CP*GP*AP*CP*GP*GP*AP*GP*GP*AP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*GP*CP*TP*CP*CP*TP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... | Authors: | Koag, M.-C, Lee, S. | Deposit date: | 2016-01-11 | Release date: | 2017-01-18 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.363 Å) | Cite: | Synthesis, structure, and biological evaluation of a platinum-carbazole conjugate. Chem Biol Drug Des, 91, 2018
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7X1K
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![BU of 7x1k by Molmil](/molmil-images/mine/7x1k) | |
4M8A
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![BU of 4m8a by Molmil](/molmil-images/mine/4m8a) | Crystal Structure of Thermotoga maritima FtsH Periplasmic Domain | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ATP-dependent zinc metalloprotease FtsH | Authors: | An, J.Y, Sharif, H, Barrera, F.N, Karabadzhak, A, Kang, G.B, Park, K.J, Sakkiah, S, Lee, K.W, Lee, S, Engelman, D.M, Wang, J, Eom, S.H. | Deposit date: | 2013-08-13 | Release date: | 2014-09-17 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.502 Å) | Cite: | Structural roles of periplasmic and transmembrane domains of FtsH in ATP-dependent proteolysis To be Published
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7EPP
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![BU of 7epp by Molmil](/molmil-images/mine/7epp) | |
6JCM
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![BU of 6jcm by Molmil](/molmil-images/mine/6jcm) | Crystal structure of ligand-free Rv0187. | Descriptor: | ACETATE ION, Probable O-methyltransferase | Authors: | Kim, J, Lee, S. | Deposit date: | 2019-01-29 | Release date: | 2019-12-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Structural and biochemical characterization of Rv0187, an O-methyltransferase from Mycobacterium tuberculosis. Sci Rep, 9, 2019
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6JCL
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![BU of 6jcl by Molmil](/molmil-images/mine/6jcl) | Crystal structure of cofactor-bound Rv0187 from MTB | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Probable O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Kim, J, Lee, S. | Deposit date: | 2019-01-29 | Release date: | 2019-12-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.644 Å) | Cite: | Structural and biochemical characterization of Rv0187, an O-methyltransferase from Mycobacterium tuberculosis. Sci Rep, 9, 2019
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6LHS
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![BU of 6lhs by Molmil](/molmil-images/mine/6lhs) | High resolution structure of FANCA C-terminal domain (CTD) | Descriptor: | Fanconi anemia complementation group A | Authors: | Jeong, E, Lee, S, Shin, J, Kim, Y, Scharer, O, Kim, Y, Kim, H, Cho, Y. | Deposit date: | 2019-12-10 | Release date: | 2020-03-25 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex. Nucleic Acids Res., 48, 2020
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6LHU
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![BU of 6lhu by Molmil](/molmil-images/mine/6lhu) | High resolution structure of FANCA C-terminal domain (CTD) | Descriptor: | Fanconi anemia complementation group A | Authors: | Jeong, E, Lee, S, Shin, J, Kim, Y, Kim, J, Scharer, O, Kim, Y, Kim, H, Cho, Y. | Deposit date: | 2019-12-10 | Release date: | 2020-03-25 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex. Nucleic Acids Res., 48, 2020
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1C3G
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![BU of 1c3g by Molmil](/molmil-images/mine/1c3g) | S. CEREVISIAE HEAT SHOCK PROTEIN 40 SIS1 | Descriptor: | HEAT SHOCK PROTEIN 40 | Authors: | Sha, B, Lee, S, Cyr, D. | Deposit date: | 1999-07-27 | Release date: | 2000-08-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The crystal structure of the peptide-binding fragment from the yeast Hsp40 protein Sis1. Structure, 8, 2000
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1B66
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![BU of 1b66 by Molmil](/molmil-images/mine/1b66) | 6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE | Descriptor: | 6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE, BIOPTERIN, ZINC ION | Authors: | Ploom, T, Thoeny, B, Yim, J, Lee, S, Nar, H, Leimbacher, W, Huber, R, Richardson, J, Auerbach, G. | Deposit date: | 1999-01-20 | Release date: | 1999-04-27 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystallographic and kinetic investigations on the mechanism of 6-pyruvoyl tetrahydropterin synthase. J.Mol.Biol., 286, 1999
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1B6Z
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![BU of 1b6z by Molmil](/molmil-images/mine/1b6z) | 6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE | Descriptor: | 6-pyruvoyl tetrahydropterin synthase, ZINC ION | Authors: | Ploom, T, Thoeny, B, Yim, J, Lee, S, Nar, H, Leimbacher, W, Huber, R, Richardson, J, Auerbach, G. | Deposit date: | 1999-01-18 | Release date: | 2000-01-21 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystallographic and kinetic investigations on the mechanism of 6-pyruvoyl tetrahydropterin synthase. J.Mol.Biol., 286, 1999
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7FD4
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![BU of 7fd4 by Molmil](/molmil-images/mine/7fd4) | A complete three-dimensional structure of the Lon protease translocating a protein substrate (conformation 1) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Alpha-S1-casein, Lon protease, ... | Authors: | Li, S, Hsieh, K, Kuo, C, Lee, S, Pintilie, G, Zhang, K, Chang, C. | Deposit date: | 2021-07-16 | Release date: | 2021-11-03 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Complete three-dimensional structures of the Lon protease translocating a protein substrate. Sci Adv, 7, 2021
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7FD5
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![BU of 7fd5 by Molmil](/molmil-images/mine/7fd5) | A complete three-dimensional structure of the Lon protease translocating a protein substrate (conformation 2) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Alpha-S1-casein, Lon protease, ... | Authors: | Li, S, Hsieh, K, Kuo, C, Lee, S, Pintilie, G, Zhang, K, Chang, C. | Deposit date: | 2021-07-16 | Release date: | 2021-11-03 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Complete three-dimensional structures of the Lon protease translocating a protein substrate. Sci Adv, 7, 2021
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1IA5
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![BU of 1ia5 by Molmil](/molmil-images/mine/1ia5) | POLYGALACTURONASE FROM ASPERGILLUS ACULEATUS | Descriptor: | POLYGALACTURONASE, alpha-D-mannopyranose, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Cho, S.W, Lee, S, Shin, W. | Deposit date: | 2001-03-22 | Release date: | 2001-09-19 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The X-ray structure of Aspergillus aculeatus polygalacturonase and a modeled structure of the polygalacturonase-octagalacturonate complex. J.Mol.Biol., 311, 2001
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7FDA
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![BU of 7fda by Molmil](/molmil-images/mine/7fda) | CryoEM Structure of Reconstituted V-ATPase, state1 | Descriptor: | Fusion of yeast V-type proton ATPase subunit H(NT) and human V-type proton ATPase subunit H(CT), V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | Authors: | Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H. | Deposit date: | 2021-07-16 | Release date: | 2021-12-22 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation. Embo J., 2021
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