5HHH
Structure of human DNA polymerase beta Host-Guest complexed with the control G for N7-CBZ-platination
Summary for 5HHH
Entry DOI | 10.2210/pdb5hhh/pdb |
Related | 5HHI |
Descriptor | DNA polymerase beta, DNA (5'-D(*CP*CP*GP*AP*CP*GP*GP*AP*GP*GP*AP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*GP*CP*TP*CP*CP*TP*C)-3'), ... (6 entities in total) |
Functional Keywords | transferase, lyase-dna complex, lyase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 46823.70 |
Authors | Koag, M.-C.,Lee, S. (deposition date: 2016-01-11, release date: 2017-01-18, Last modification date: 2023-09-27) |
Primary citation | Cheun, Y.,Koag, M.C.,Naguib, Y.W.,Ouzon-Shubeita, H.,Cui, Z.,Pakotiprapha, D.,Lee, S. Synthesis, structure, and biological evaluation of a platinum-carbazole conjugate. Chem Biol Drug Des, 91:116-125, 2018 Cited by PubMed: 28649747DOI: 10.1111/cbdd.13062 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.363 Å) |
Structure validation
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