1C3G

S. CEREVISIAE HEAT SHOCK PROTEIN 40 SIS1

Summary for 1C3G

• Entry DOI: 10.2210/pdb1c3g/pdb
• Descriptor: HEAT SHOCK PROTEIN 40 (2 entities in total)
• Functional Keywords: beta sheets, short helices, chaperone
• Biological source: Saccharomyces cerevisiae (baker's yeast)
• Cellular location: Cytoplasm : P25294
• Total number of polymer chains: 1
• Total formula weight: 19097.80

Authors

Sha, B.,Lee, S.,Cyr, D. (deposition date: 1999-07-27, release date: 2000-08-03, Last modification date: 2024-02-07)

Primary citation

Sha, B.,Lee, S.,Cyr, D.M.
The crystal structure of the peptide-binding fragment from the yeast Hsp40 protein Sis1.
Structure, 8:799-807, 2000

PubMed Abstract: Molecular chaperone Hsp40 can bind non-native polypeptide and facilitate Hsp70 in protein refolding. How Hsp40 and other chaperones distinguish between the folded and unfolded states of proteins to bind nonnative polypeptides is a fundamental issue.

PubMed: 10997899
DOI: 10.1107/S090744499900476X

Experimental method

X-RAY DIFFRACTION (2.7 Å)