1Z5N
| Crystal structure of MTA/AdoHcy nucleosidase Glu12Gln mutant complexed with 5-methylthioribose and adenine | Descriptor: | 5-S-methyl-5-thio-alpha-D-ribofuranose, ADENINE, MTA/SAH nucleosidase | Authors: | Lee, J.E, Smith, G.D, Horvatin, C, Huang, D.J.T, Cornell, K.A, Riscoe, M.K, Howell, P.L. | Deposit date: | 2005-03-18 | Release date: | 2005-10-04 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural snapshots of MTA/AdoHcy nucleosidase along the reaction coordinate provide insights into enzyme and nucleoside flexibility during catalysis J.Mol.Biol., 352, 2005
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2AOR
| Crystal structure of MutH-hemimethylated DNA complex | Descriptor: | 5'-D(*CP*AP*GP*GP*(6MA)P*TP*CP*CP*AP*AP*GP*CP*TP*TP*GP*GP*AP*TP*CP*CP*TP*G)-3', CALCIUM ION, DNA mismatch repair protein mutH | Authors: | Lee, J.Y, Chang, J, Joseph, N, Ghirlando, R, Rao, D.N, Yang, W. | Deposit date: | 2005-08-13 | Release date: | 2005-10-11 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | MutH complexed with hemi- and unmethylated DNAs: coupling base recognition and DNA cleavage. Mol.Cell, 20, 2005
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1VC1
| Crystal structure of the TM1442 protein from Thermotoga maritima, a homolog of the Bacillus subtilis general stress response anti-anti-sigma factor RsbV | Descriptor: | Putative anti-sigma factor antagonist TM1442 | Authors: | Lee, J.Y, Ahn, H.J, Ha, K.S, Suh, S.W. | Deposit date: | 2004-03-03 | Release date: | 2004-09-28 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of the TM1442 protein from Thermotoga maritima, a homolog of the Bacillus subtilis general stress response anti-anti-sigma factor RsbV Proteins, 56, 2004
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1QL5
| DNA DECAMER DUPLEX CONTAINING T5-T6 PHOTOADDUCT | Descriptor: | DNA (5'-D(*CP*GP*CP*AP*TP*+TP*AP*CP*GP*C)- 3'), DNA (5'-D(*GP*CP*GP*TP*TP*AP*TP*GP*CP*G)-3') | Authors: | Lee, J.-H, Hwang, G.-S, Choi, B.-S. | Deposit date: | 1999-08-24 | Release date: | 2000-04-10 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution Structure of a DNA Decamer Duplex Containing the 3' T.T Base Pair of the Cis-Syn Cyclobutane Pyrimidine Dimer: Implication for the Mutagenic Property of the Cis-Syn Dimer. Nucleic Acids Res., 28, 2000
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3VF0
| Raver1 in complex with metavinculin L954 deletion mutant | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Ribonucleoprotein PTB-binding 1, ... | Authors: | Lee, J.H, Vonrhein, C, Bricogne, G, Izard, T. | Deposit date: | 2012-01-09 | Release date: | 2012-07-25 | Last modified: | 2012-09-19 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | The Metavinculin Tail Domain Directs Constitutive Interactions with Raver1 and vinculin RNA. J.Mol.Biol., 422, 2012
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1QKG
| DNA DECAMER DUPLEX CONTAINING T-T DEWAR PHOTOPRODUCT | Descriptor: | DNA (5'-D(*CP*GP*CP*AP*(HYD)TP*+TP*AP*CP*GP*C)-3'), DNA (5'-D(*GP*CP*GP*TP*GP*AP*TP*GP*CP*G)-3') | Authors: | Lee, J.-H, Bae, S.-H, Choi, Y.-J, Choi, B.-S. | Deposit date: | 1999-07-20 | Release date: | 2000-05-11 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The Dewar Photoproduct of Thymidylyl(3'-->5')-Thymidine (Dewar Product) Exhibits Mutagenic Behavior in Accordance with the "A Rule". Proc.Natl.Acad.Sci.USA, 97, 2000
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5T42
| Structure of the Ebola virus envelope protein MPER/TM domain and its interaction with the fusion loop explains their fusion activity | Descriptor: | Envelope glycoprotein | Authors: | Lee, J, Nyenhuis, D.A, Nelson, E.A, Cafiso, D.S, White, J.M, Tamm, L.K. | Deposit date: | 2016-08-28 | Release date: | 2017-08-30 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure of the Ebola virus envelope protein MPER/TM domain and its interaction with the fusion loop explains their fusion activity. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5UMV
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2EVU
| Crystal structure of aquaporin AqpM at 2.3A resolution | Descriptor: | Aquaporin aqpM, GLYCEROL, octyl beta-D-glucopyranoside | Authors: | Lee, J.K, Kozono, D, Remis, J, Kitagawa, Y, Agre, P, Stroud, R.M, Center for Structures of Membrane Proteins (CSMP) | Deposit date: | 2005-10-31 | Release date: | 2005-12-06 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for conductance by the archaeal aquaporin AqpM at 1.68 A. Proc.Natl.Acad.Sci.Usa, 102, 2005
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3C4B
| Structure of RNaseIIIb and dsRNA binding domains of mouse Dicer | Descriptor: | Endoribonuclease Dicer | Authors: | Lee, J.K, Du, Z, Tjhen, R.J, Stroud, R.M, James, T.L. | Deposit date: | 2008-01-29 | Release date: | 2008-02-19 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Structural and biochemical insights into the dicing mechanism of mouse Dicer: A conserved lysine is critical for dsRNA cleavage. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3HL4
| Crystal structure of a mammalian CTP:phosphocholine cytidylyltransferase with CDP-choline | Descriptor: | Choline-phosphate cytidylyltransferase A, FORMIC ACID, GLYCEROL, ... | Authors: | Lee, J, Paetzel, M, Cornell, R.B. | Deposit date: | 2009-05-26 | Release date: | 2009-09-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of a mammalian CTP: Phosphocholine cytidylyltransferase catalytic domain reveals novel active site residues within a highly conserved nucleotidyl-transferase fold J.Biol.Chem., 284, 2009
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3C4T
| Structure of RNaseIIIb and dsRNA binding domains of mouse Dicer | Descriptor: | CADMIUM ION, Endoribonuclease Dicer | Authors: | Lee, J.K, Du, Z, Tjhen, R.J, Stroud, R.M, James, T.L. | Deposit date: | 2008-01-30 | Release date: | 2008-02-19 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural and biochemical insights into the dicing mechanism of mouse Dicer: A conserved lysine is critical for dsRNA cleavage. Proc.Natl.Acad.Sci.Usa, 105, 2008
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6KHD
| Crystal structure of CLK1 in complex with CX-4945 | Descriptor: | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid, Dual specificity protein kinase CLK1 | Authors: | Lee, J.Y, Yun, J.S, Jin, H, Chang, J.H. | Deposit date: | 2019-07-15 | Release date: | 2019-10-02 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Basis for the Selective Inhibition of Cdc2-Like Kinases by CX-4945. Biomed Res Int, 2019, 2019
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4MRP
| Structure of a bacterial Atm1-family ABC transporter | Descriptor: | ABC transporter related protein, GLUTATHIONE, LAURYL DIMETHYLAMINE-N-OXIDE, ... | Authors: | Lee, J.Y, Yang, J.G, Zhitnitsky, D, Lewinson, O, Rees, D.C. | Deposit date: | 2013-09-17 | Release date: | 2014-03-19 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for heavy metal detoxification by an Atm1-type ABC exporter. Science, 343, 2014
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5AWN
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5CCK
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3NE2
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2AOQ
| Crystal structure of MutH-unmethylated DNA complex | Descriptor: | 5'-D(*GP*CP*AP*TP*GP*AP*TP*CP*AP*TP*GP*C)-3', CALCIUM ION, DNA mismatch repair protein mutH | Authors: | Lee, J.Y, Chang, J, Joseph, N, Ghirlando, R, Rao, D.N, Yang, W. | Deposit date: | 2005-08-13 | Release date: | 2005-10-11 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | MutH complexed with hemi- and unmethylated DNAs: coupling base recognition and DNA cleavage. Mol.Cell, 20, 2005
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4MVD
| Crystal Structure of a Mammalian Cytidylyltransferase | Descriptor: | Choline-phosphate cytidylyltransferase A, [2-CYTIDYLATE-O'-PHOSPHONYLOXYL]-ETHYL-TRIMETHYL-AMMONIUM | Authors: | Lee, J, Cornell, R.B. | Deposit date: | 2013-09-23 | Release date: | 2013-12-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (8 Å) | Cite: | Structural Basis for Autoinhibition of CTP:Phosphocholine Cytidylyltransferase (CCT), the Regulatory Enzyme in Phosphatidylcholine Synthesis, by Its Membrane-binding Amphipathic Helix. J.Biol.Chem., 289, 2014
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7CM0
| Crystal structure of a glutaminyl cyclase in complex with NHV-1009 | Descriptor: | 1-(cyclopentylmethyl)-1-[3-methoxy-4-(2-morpholin-4-ylethoxy)phenyl]-3-[3-(5-methylimidazol-1-yl)propyl]urea, Glutaminyl-peptide cyclotransferase, ZINC ION | Authors: | Lee, J.W, Song, J.Y, Jang, T.H, Ha, J.H. | Deposit date: | 2020-07-23 | Release date: | 2021-12-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Discovery of highly potent human glutaminyl cyclase (QC) inhibitors as anti-Alzheimer's agents by the combination of pharmacophore-based and structure-based design. Eur.J.Med.Chem., 226, 2021
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2B02
| Crystal Structure of ARNT PAS-B Domain | Descriptor: | Aryl hydrocarbon receptor nuclear translocator | Authors: | Lee, J, Botuyan, M.V, Nomine, Y, Ohh, M, Thompson, J.R, Mer, G. | Deposit date: | 2005-09-12 | Release date: | 2006-10-24 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal Structure and Binding Properties of ARNT PAS-B Heterodimerization Domain To be Published
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1XTB
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3QJN
| Structural flexibility of Shank PDZ domain is important for its binding to different ligands | Descriptor: | Beta-PIX, SH3 and multiple ankyrin repeat domains protein 1 | Authors: | Lee, J.H, Park, H, Park, S.J, Kim, H.J, Eom, S.H. | Deposit date: | 2011-01-30 | Release date: | 2011-04-13 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | The structural flexibility of the shank1 PDZ domain is important for its binding to different ligands Biochem.Biophys.Res.Commun., 407, 2011
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2F2B
| Crystal structure of integral membrane protein Aquaporin AqpM at 1.68A resolution | Descriptor: | Aquaporin aqpM, GLYCEROL | Authors: | Lee, J.K, Kozono, D, Remis, J, Kitagawa, Y, Agre, P, Stroud, R.M, Center for Structures of Membrane Proteins (CSMP) | Deposit date: | 2005-11-15 | Release date: | 2005-12-06 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Structural basis for conductance by the archaeal aquaporin AqpM at 1.68 A. Proc.Natl.Acad.Sci.Usa, 102, 2005
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7UJA
| Cryo-EM structure of Human respiratory syncytial virus F variant (construct pXCS847A) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, AM14 Fab heavy chain, AM14 Fab light chain, ... | Authors: | Lees, J.A, Ammirati, M, Han, S. | Deposit date: | 2022-03-30 | Release date: | 2023-04-19 | Last modified: | 2023-05-10 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Rational design of a highly immunogenic prefusion-stabilized F glycoprotein antigen for a respiratory syncytial virus vaccine. Sci Transl Med, 15, 2023
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