1Z5N

Crystal structure of MTA/AdoHcy nucleosidase Glu12Gln mutant complexed with 5-methylthioribose and adenine

Summary for 1Z5N

Entry DOI	10.2210/pdb1z5n/pdb
Related	1Z5O 1Z5P
Descriptor	MTA/SAH nucleosidase, 5-S-methyl-5-thio-alpha-D-ribofuranose, ADENINE, ... (4 entities in total)
Functional Keywords	mixed alpha/beta, hydrolase
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	51604.98
Authors	Lee, J.E.,Smith, G.D.,Horvatin, C.,Huang, D.J.T.,Cornell, K.A.,Riscoe, M.K.,Howell, P.L. (deposition date: 2005-03-18, release date: 2005-10-04, Last modification date: 2023-08-23)
Primary citation	Lee, J.E.,Smith, G.D.,Horvatin, C.,Huang, D.J.T.,Cornell, K.A.,Riscoe, M.K.,Howell, P.L. Structural snapshots of MTA/AdoHcy nucleosidase along the reaction coordinate provide insights into enzyme and nucleoside flexibility during catalysis J.Mol.Biol., 352:559-574, 2005 Cited by PubMed: 16109423 DOI: 10.1016/j.jmb.2005.07.027 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation