6OG2
 
 | | Focus classification structure of the hyperactive ClpB mutant K476C, bound to casein, post-state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Hyperactive disaggregase ClpB | | Authors: | Rizo, A.R, Lin, J.-B, Gates, S.N, Tse, E, Bart, S.M, Castellano, L.M, Dimaio, F, Shorter, J, Southworth, D.R. | | Deposit date: | 2019-04-01 | | Release date: | 2019-06-12 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structural basis for substrate gripping and translocation by the ClpB AAA+ disaggregase.
Nat Commun, 10, 2019
|
|
6TYL
 | | Crystal structure of mammalian Ric-8A:Galpha(i):nanobody complex | | Descriptor: | Guanine nucleotide-binding protein G(i) subunit alpha-1, Nanobody A, Nanobody B, ... | | Authors: | Mou, T.C, McClelland, L, Yates-Hansen, C, Sprang, S.R. | | Deposit date: | 2019-08-09 | | Release date: | 2020-03-11 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structure of the G protein chaperone and guanine nucleotide exchange factor Ric-8A bound to G alpha i1.
Nat Commun, 11, 2020
|
|
1XHZ
 | | Phi29 DNA polymerase, orthorhombic crystal form, ssDNA complex | | Descriptor: | 5'-D(*TP*TP*TP*TP*T)-3', DNA polymerase | | Authors: | Kamtekar, S, Berman, A.J, Wang, J, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A. | | Deposit date: | 2004-09-21 | | Release date: | 2004-12-07 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Insights into Strand Displacement and Processivity from the Crystal Structure of the Protein-Primed DNA Polymerase of Bacteriophage phi29
Mol.Cell, 16, 2004
|
|
6OG3
 | | Focus classification structure of the hyperactive ClpB mutant K476C, bound to casein, NTD-trimer | | Descriptor: | Alpha S1-casein, Hyperactive disaggregase ClpB | | Authors: | Rizo, A.R, Lin, J.-B, Gates, S.N, Tse, E, Bart, S.M, Castellano, L.M, Dimaio, F, Shorter, J, Southworth, D.R. | | Deposit date: | 2019-04-01 | | Release date: | 2019-06-12 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structural basis for substrate gripping and translocation by the ClpB AAA+ disaggregase.
Nat Commun, 10, 2019
|
|
6AS9
 | | Filamentous Assembly of Green Fluorescent Protein Supported by a C-terminal fusion of 18-residues, viewed in space group P212121 form 2 | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, Green fluorescent protein | | Authors: | Sawaya, M.R, Heller, D.M, McPartland, L, Hochschild, A, Eisenberg, D.S. | | Deposit date: | 2017-08-23 | | Release date: | 2018-05-30 | | Last modified: | 2019-11-20 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Atomic insights into the genesis of cellular filaments by globular proteins.
Nat. Struct. Mol. Biol., 25, 2018
|
|
1R6T
 | | crystal structure of human tryptophanyl-tRNA synthetase | | Descriptor: | GLYCEROL, TRYPTOPHANYL-5'AMP, Tryptophanyl-tRNA synthetase | | Authors: | Yang, X.-L, Otero, F.J, Skene, R.J, McRee, D.E, Ribas de Pouplana, L, Schimmel, P. | | Deposit date: | 2003-10-16 | | Release date: | 2004-01-06 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structures that suggest late development of genetic code components for differentiating aromatic side chains
Proc.Natl.Acad.Sci.USA, 100, 2003
|
|
1R6U
 | | Crystal structure of an active fragment of human tryptophanyl-tRNA synthetase with cytokine activity | | Descriptor: | GLYCEROL, TRYPTOPHANYL-5'AMP, Tryptophanyl-tRNA synthetase | | Authors: | Yang, X.-L, Otero, F.J, Skene, R.J, McRee, D.E, Ribas de Pouplana, L, Schimmel, P. | | Deposit date: | 2003-10-16 | | Release date: | 2004-01-06 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Functional and crystal structure analysis of active site adaptations of a potent anti-angiogenic human tRNA synthetase
Structure, 15, 2007
|
|
7ZU0
 | | HOPS tethering complex from yeast | | Descriptor: | E3 ubiquitin-protein ligase PEP5, Vacuolar membrane protein PEP3, Vacuolar morphogenesis protein 6, ... | | Authors: | Shvarev, D, Schoppe, J, Koenig, C, Perz, A, Fuellbrunn, N, Kiontke, S, Langemeyer, L, Januliene, D, Schnelle, K, Kuemmel, D, Froehlich, F, Moeller, A, Ungermann, C. | | Deposit date: | 2022-05-11 | | Release date: | 2022-09-28 | | Last modified: | 2022-10-12 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Structure of the HOPS tethering complex, a lysosomal membrane fusion machinery.
Elife, 11, 2022
|
|
1NZP
 | | Solution Structure of the Lyase Domain of Human DNA Polymerase Lambda | | Descriptor: | DNA polymerase lambda | | Authors: | DeRose, E.F, Kirby, T.W, Mueller, G.A, Bebenek, K, Garcia-Diaz, M, Blanco, L, Kunkel, T.A, London, R.E. | | Deposit date: | 2003-02-19 | | Release date: | 2003-08-05 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of the Lyase Domain of Human DNA Polymerase Lambda
Biochemistry, 42, 2003
|
|
1RIQ
 | | The crystal structure of the catalytic fragment of the alanyl-tRNA synthetase | | Descriptor: | Alanyl-tRNA synthetase | | Authors: | Swairjo, M.A, Otero, F.J, Yang, X.-L, Lovato, M.A, Skene, R.J, McRee, D.E, Ribas de Pouplana, L, Schimmel, P. | | Deposit date: | 2003-11-17 | | Release date: | 2004-04-06 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.14 Å) | | Cite: | Alanyl-tRNA Synthetase Crystal Structure and Design for Acceptor-Stem Recognition
Mol.Cell, 13, 2004
|
|
4BD4
 | | Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, mutant H43F | | Descriptor: | GLYCEROL, SUPEROXIDE DISMUTASE [CU-ZN] | | Authors: | Awad, W, Saraboji, K, Danielsson, J, Lang, L, Kurnik, M, Marklund, S.L, Oliveberg, M, Logan, D.T. | | Deposit date: | 2012-10-04 | | Release date: | 2013-02-27 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.78 Å) | | Cite: | Global Structural Motions from the Strain of a Single Hydrogen Bond.
Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
4BCZ
 | | Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form. | | Descriptor: | SUPEROXIDE DISMUTASE [CU-ZN] | | Authors: | Saraboji, K, Awad, W, Danielsson, J, Lang, L, Kurnik, M, Marklund, S.L, Oliveberg, M, Logan, D.T. | | Deposit date: | 2012-10-03 | | Release date: | 2013-02-27 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Global Structural Motions from the Strain of a Single Hydrogen Bond.
Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
4BCY
 | | Monomeric Human Cu,Zn Superoxide dismutase, mutation H43F | | Descriptor: | CADMIUM ION, CHLORIDE ION, COPPER (II) ION, ... | | Authors: | Awad, W, Saraboji, K, Danielsson, J, Lang, L, Kurnik, M, Marklund, S.L, Oliveberg, M, Logan, D.T. | | Deposit date: | 2012-10-03 | | Release date: | 2013-02-27 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.272 Å) | | Cite: | Global Structural Motions from the Strain of a Single Hydrogen Bond.
Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
4XCR
 | | Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, mutant I35A | | Descriptor: | Superoxide dismutase [Cu-Zn] | | Authors: | Wang, H, Logan, D.T, Danielsson, J, Mu, X, Binolfi, A, Theillet, F, Bekei, B, Lang, L, Wennerstrom, H, Selenko, P, Oliveberg, M. | | Deposit date: | 2014-12-18 | | Release date: | 2016-01-20 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.602 Å) | | Cite: | Thermodynamics of protein destabilization in live cells.
Proc. Natl. Acad. Sci. U.S.A., 112, 2015
|
|
4C3O
 | | Structure and function of an oxygen tolerant NiFe hydrogenase from Salmonella | | Descriptor: | CHLORIDE ION, FE3-S4 CLUSTER, FE4-S3 CLUSTER, ... | | Authors: | Bowman, L, Flanagan, L, Fyfe, P.K, Parkin, A, Hunter, W.N, Sargent, F. | | Deposit date: | 2013-08-26 | | Release date: | 2014-01-29 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | How the Structure of the Large Subunit Controls Function in an Oxygen-Tolerant [Nife]-Hydrogenase.
Biochem.J., 458, 2014
|
|
5DFS
 | | Crystal structure of Spider Monkey Cytochrome C at 1.15 Angstrom | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Cytochrome c, ... | | Authors: | MOU, T.C, McClelland, L.J, Jeakins-Cooley, M.E, Goldes, M.E, SPRANG, S.R, BOWLER, B.E. | | Deposit date: | 2015-08-27 | | Release date: | 2016-03-02 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.15 Å) | | Cite: | Disruption of a hydrogen bond network in human versus spider monkey cytochrome c affects heme crevice stability.
J.Inorg.Biochem., 158, 2016
|
|
1S62
 | | Solution structure of the Escherichia coli TolA C-terminal domain | | Descriptor: | TolA protein | | Authors: | Deprez, C, Blanchard, L, Simorre, J.-P, Gavioli, M, Guerlesquin, F, Lazdunski, C, Lloubes, R, Marion, D. | | Deposit date: | 2004-01-22 | | Release date: | 2005-02-15 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the E.coli TolA C-terminal domain reveals conformational changes upon binding to the phage g3p N-terminal domain.
J.Mol.Biol., 346, 2005
|
|
2WHS
 | | Fluorescent Protein mKeima at pH 3.8 | | Descriptor: | LARGE STOKES SHIFT FLUORESCENT PROTEIN, SULFATE ION | | Authors: | Violot, S, Carpentier, P, Blanchoin, L, Bourgeois, D. | | Deposit date: | 2009-05-06 | | Release date: | 2009-08-11 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Reverse Ph-Dependence of Chromophore Protonation Explains the Large Stokes Shift of the Red Fluorescent Protein Mkeima.
J.Am.Chem.Soc., 131, 2009
|
|
4DZT
 | | Aqualysin I: the crystal structure of a serine protease from an extreme thermophile, Thermus aquaticus YT-1 | | Descriptor: | Aqualysin-1, CALCIUM ION, phenylmethanesulfonic acid | | Authors: | Barnett, B.L, Green, P.R, Strickland, L.C, Oliver, J.D, Rydel, T, Sullivan, J.F. | | Deposit date: | 2012-03-01 | | Release date: | 2012-03-28 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Aqualysin I: the crystal structure of a serine protease from an extreme thermophile, Thermus aquaticus YT-1
To be Published
|
|
4IYE
 | | Crystal structure of AdTx1 (rho-Da1a) from eastern green mamba (Dendroaspis angusticeps) | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Toxin AdTx1 | | Authors: | Stura, E.A, Vera, L, Maiga, A.A, Marchetti, C, Lorphelin, A, Bellanger, L, Servant, D, Gilles, N. | | Deposit date: | 2013-01-28 | | Release date: | 2013-05-08 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.951 Å) | | Cite: | Crystallization of recombinant green mamba rho-Da1a toxin during a lyophilization procedure and its structure determination.
Acta Crystallogr.,Sect.F, 69, 2013
|
|
5SB7
 | | Tubulin-todalam-18-complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Muehlethaler, T, Milanos, L, Ortega, J.A, Blum, T.B, Gioia, D, Prota, A.E, Cavalli, A, Steinmetz, M.O. | | Deposit date: | 2021-07-08 | | Release date: | 2022-04-27 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Rational Design of a Novel Tubulin Inhibitor with a Unique Mechanism of Action.
Angew.Chem.Int.Ed.Engl., 61, 2022
|
|
5SB6
 | | Tubulin-todalam-10-complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Muehlethaler, T, Milanos, L, Ortega, J.A, Blum, T.B, Gioia, D, Prota, A.E, Cavalli, A, Steinmetz, M.O. | | Deposit date: | 2021-07-08 | | Release date: | 2022-04-27 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Rational Design of a Novel Tubulin Inhibitor with a Unique Mechanism of Action.
Angew.Chem.Int.Ed.Engl., 61, 2022
|
|
5SB3
 | | Tubulin-todalam-4-complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Muehlethaler, T, Milanos, L, Ortega, J.A, Blum, T.B, Gioia, D, Prota, A.E, Cavalli, A, Steinmetz, M.O. | | Deposit date: | 2021-07-08 | | Release date: | 2022-04-27 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Rational Design of a Novel Tubulin Inhibitor with a Unique Mechanism of Action.
Angew.Chem.Int.Ed.Engl., 61, 2022
|
|
5SB5
 | | Tubulin-todalam-9-complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Muehlethaler, T, Milanos, L, Ortega, J.A, Blum, T.B, Gioia, D, Prota, A.E, Cavalli, A, Steinmetz, M.O. | | Deposit date: | 2021-07-08 | | Release date: | 2022-04-27 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | Rational Design of a Novel Tubulin Inhibitor with a Unique Mechanism of Action.
Angew.Chem.Int.Ed.Engl., 61, 2022
|
|
5SB4
 | | Tubulin-todalam-8-complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Muehlethaler, T, Milanos, L, Ortega, J.A, Blum, T.B, Gioia, D, Prota, A.E, Cavalli, A, Steinmetz, M.O. | | Deposit date: | 2021-07-08 | | Release date: | 2022-04-27 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Rational Design of a Novel Tubulin Inhibitor with a Unique Mechanism of Action.
Angew.Chem.Int.Ed.Engl., 61, 2022
|
|
