8EFN
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![BU of 8efn by Molmil](/molmil-images/mine/8efn) | Structure of Sp-STING3 from Stylophora pistillata coral in complex with 3',3'-cGAMP | Descriptor: | 1,2-ETHANEDIOL, 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, Stimulator of interferon genes protein | Authors: | Li, Y, Slavik, K.M, Morehouse, B.R, Mears, K, Kranzusch, P.J. | Deposit date: | 2022-09-08 | Release date: | 2023-07-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | cGLRs are a diverse family of pattern recognition receptors in innate immunity. Cell, 186, 2023
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1BM6
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![BU of 1bm6 by Molmil](/molmil-images/mine/1bm6) | SOLUTION STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN STROMELYSIN-1 COMPLEXED TO A POTENT NON-PEPTIDIC INHIBITOR, NMR, 20 STRUCTURES | Descriptor: | 1-METHYLOXY-4-SULFONE-BENZENE, 3-METHYLPYRIDINE, CALCIUM ION, ... | Authors: | Li, Y, Zhang, X, Melton, R, Ganu, V, Gonnella, N.C. | Deposit date: | 1998-07-29 | Release date: | 1999-07-29 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the catalytic domain of human stromelysin-1 complexed to a potent, nonpeptidic inhibitor. Biochemistry, 37, 1998
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7KPW
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![BU of 7kpw by Molmil](/molmil-images/mine/7kpw) | Structure of the H-lobe of yeast CKM | Descriptor: | Mediator of RNA polymerase II transcription subunit 12 | Authors: | Li, Y.C, Chao, T.C, Kim, H.J, Cholko, T, Chen, S.F, Nakanishi, K, Chang, C.E, Murakami, K, Garcia, B.A, Boyer, T.G, Tsai, K.L. | Deposit date: | 2020-11-12 | Release date: | 2021-01-27 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module. Sci Adv, 7, 2021
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7KPX
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![BU of 7kpx by Molmil](/molmil-images/mine/7kpx) | Structure of the yeast CKM | Descriptor: | Mediator of RNA polymerase II transcription subunit 12, Mediator of RNA polymerase II transcription subunit 13, Meiotic mRNA stability protein kinase SSN3, ... | Authors: | Li, Y.C, Chao, T.C, Kim, H.J, Cholko, T, Chen, S.F, Nakanishi, K, Chang, C.E, Murakami, K, Garcia, B.A, Boyer, T.G, Tsai, K.L. | Deposit date: | 2020-11-12 | Release date: | 2021-01-27 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module. Sci Adv, 7, 2021
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7KPV
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![BU of 7kpv by Molmil](/molmil-images/mine/7kpv) | Structure of kinase and Central lobes of yeast CKM | Descriptor: | Mediator of RNA polymerase II transcription subunit 12, Mediator of RNA polymerase II transcription subunit 13, Meiotic mRNA stability protein kinase SSN3, ... | Authors: | Li, Y.C, Chao, T.C, Kim, H.J, Cholko, T, Chen, S.F, Nakanishi, K, Chang, C.E, Murakami, K, Garcia, B.A, Boyer, T.G, Tsai, K.L. | Deposit date: | 2020-11-12 | Release date: | 2021-01-27 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module. Sci Adv, 7, 2021
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1XGP
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![BU of 1xgp by Molmil](/molmil-images/mine/1xgp) | |
1XGR
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![BU of 1xgr by Molmil](/molmil-images/mine/1xgr) | Structure for antibody HyHEL-63 Y33I mutant complexed with hen egg lysozyme | Descriptor: | Lysozyme C, antibody kappa heavy chain, antibody kappa light chain | Authors: | Li, Y, Huang, Y, Swaminathan, C.P, Smith-Gill, S.J, Mariuzza, R.A. | Deposit date: | 2004-09-17 | Release date: | 2005-09-06 | Last modified: | 2013-10-02 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Magnitude of the hydrophobic effect at central versus peripheral sites in protein-protein interfaces Structure, 13, 2005
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1XGU
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![BU of 1xgu by Molmil](/molmil-images/mine/1xgu) | Structure for antibody HyHEL-63 Y33F mutant complexed with hen egg lysozyme | Descriptor: | Lysozyme C, antibody kappa heavy chain, antibody kappa light chain | Authors: | Li, Y, Huang, Y, Swaminathan, C.P, Smith-Gill, S.J, Mariuzza, R.A. | Deposit date: | 2004-09-17 | Release date: | 2005-09-06 | Last modified: | 2013-10-02 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Magnitude of the hydrophobic effect at central versus peripheral sites in protein-protein interfaces Structure, 13, 2005
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1KQL
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![BU of 1kql by Molmil](/molmil-images/mine/1kql) | Crystal structure of the C-terminal region of striated muscle alpha-tropomyosin at 2.7 angstrom resolution | Descriptor: | Fusion Protein of and striated muscle alpha-tropomyosin and the GCN4 leucine zipper | Authors: | Li, Y, Mui, S, Brown, J.H, Strand, J, Reshetnikova, L, Tobacman, L.S, Cohen, C. | Deposit date: | 2002-01-07 | Release date: | 2002-05-29 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The crystal structure of the C-terminal fragment of striated-muscle alpha-tropomyosin reveals a key troponin T recognition site. Proc.Natl.Acad.Sci.USA, 99, 2002
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1XGT
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![BU of 1xgt by Molmil](/molmil-images/mine/1xgt) | |
5V4B
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![BU of 5v4b by Molmil](/molmil-images/mine/5v4b) | Crystal structure of the Skp1-FBXW7-DISC1 complex | Descriptor: | DISC1 peptide, F-box/WD repeat-containing protein 7, IMIDAZOLE, ... | Authors: | Li, Y, Baillie, G.S, Hao, B. | Deposit date: | 2017-03-08 | Release date: | 2017-09-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | FBXW7 regulates DISC1 stability via the ubiquitin-proteosome system. Mol. Psychiatry, 23, 2018
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1XGQ
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![BU of 1xgq by Molmil](/molmil-images/mine/1xgq) | |
5DO2
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![BU of 5do2 by Molmil](/molmil-images/mine/5do2) | Complex structure of MERS-RBD bound with 4C2 antibody | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4C2 heavy chain, 4C2 light chain, ... | Authors: | Li, Y, Wan, Y, Liu, P, Zhao, J, Lu, G, Qi, J, Wang, Q, Lu, X, Wu, Y, Liu, W, Yuen, K.Y, Perlman, S, Gao, G.F, Yan, J. | Deposit date: | 2015-09-10 | Release date: | 2015-10-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.409 Å) | Cite: | A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein. Cell Res., 25, 2015
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8GJW
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![BU of 8gjw by Molmil](/molmil-images/mine/8gjw) | Structure of a cGAS-like receptor Cv-cGLR1 from C. virginica | Descriptor: | SULFATE ION, cGAS-like receptor 1 | Authors: | Li, Y, Morehouse, B.R, Slavik, K.M, Liu, J, Toyoda, H, Kranzusch, P.J. | Deposit date: | 2023-03-16 | Release date: | 2023-07-05 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | cGLRs are a diverse family of pattern recognition receptors in innate immunity. Cell, 186, 2023
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8GJZ
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![BU of 8gjz by Molmil](/molmil-images/mine/8gjz) | Structure of a STING receptor from S. pistillata Sp-STING1 bound to 2'3'-cUA | Descriptor: | 2'3'-cUA, Stimulator of interferon genes protein | Authors: | Li, Y, Toyoda, H, Slavik, K.M, Morehouse, B.R, Kranzusch, P.J. | Deposit date: | 2023-03-16 | Release date: | 2023-07-05 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.92 Å) | Cite: | cGLRs are a diverse family of pattern recognition receptors in innate immunity. Cell, 186, 2023
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8HM0
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![BU of 8hm0 by Molmil](/molmil-images/mine/8hm0) | F8-A22-E4 complex of MPXV in trimeric form | Descriptor: | DNA polymerase, DNA polymerase processivity factor component A20, E4R | Authors: | Li, Y.N, Shen, Y.P, Hu, Z.W, Yan, R.H. | Deposit date: | 2022-12-02 | Release date: | 2023-05-31 | Last modified: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis for the assembly of the DNA polymerase holoenzyme from a monkeypox virus variant. Sci Adv, 9, 2023
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8HLZ
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![BU of 8hlz by Molmil](/molmil-images/mine/8hlz) | F8-A22-E4 complex of MPXV in hexameric form | Descriptor: | DNA polymerase, DNA polymerase processivity factor component A20, E4R | Authors: | Li, Y.N, Shen, Y.P, Hu, Z.W, Yan, R.H. | Deposit date: | 2022-12-02 | Release date: | 2023-05-31 | Last modified: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis for the assembly of the DNA polymerase holoenzyme from a monkeypox virus variant. Sci Adv, 9, 2023
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1VF6
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![BU of 1vf6 by Molmil](/molmil-images/mine/1vf6) | 2.1 Angstrom crystal structure of the PALS-1-L27N and PATJ L27 heterodimer complex | Descriptor: | MAGUK p55 subfamily member 5, PALS1-associated tight junction protein | Authors: | Li, Y, Lavie, A, Margolis, B, Karnak, D. | Deposit date: | 2004-04-09 | Release date: | 2004-04-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for L27 domain-mediated assembly of signaling and cell polarity complexes. Embo J., 23, 2004
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6O59
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![BU of 6o59 by Molmil](/molmil-images/mine/6o59) | |
3C0F
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![BU of 3c0f by Molmil](/molmil-images/mine/3c0f) | Crystal Structure of a novel non-Pfam protein AF1514 from Archeoglobus fulgidus DSM 4304 solved by S-SAD using a Cr X-ray source | Descriptor: | Uncharacterized protein AF_1514 | Authors: | Li, Y, Bahti, P, Shaw, N, Song, G, Yin, J, Zhu, J.-Y, Zhang, H, Xu, H, Wang, B.-C, Liu, Z.-J. | Deposit date: | 2008-01-20 | Release date: | 2008-02-05 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of a novel non-Pfam protein AF1514 from Archeoglobus fulgidus DSM 4304 solved by S-SAD using a Cr X-ray source. Proteins, 71, 2008
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3D34
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![BU of 3d34 by Molmil](/molmil-images/mine/3d34) | Structure of the F-spondin domain of mindin | Descriptor: | CALCIUM ION, NICKEL (II) ION, Spondin-2 | Authors: | Li, Y, Mariuzza, R.A. | Deposit date: | 2008-05-09 | Release date: | 2009-02-17 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of the F-spondin domain of mindin, an integrin ligand and pattern recognition molecule. Embo J., 28, 2009
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8J4I
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![BU of 8j4i by Molmil](/molmil-images/mine/8j4i) | Unveiling the Role of Human Prohibitin 2 as a Mitochondrial Calcium Channel in Parkinson's Disease | Descriptor: | Prohibitin-2 | Authors: | Li, Y.Y, Fang, Y, Gao, Y.X, Ding, W, Yang, J, Liu, Y, Shen, B, Wang, J.F, Zhou, S. | Deposit date: | 2023-04-20 | Release date: | 2024-06-05 | Method: | SOLUTION NMR | Cite: | Human Prohibitin 2 is a Mitochondrial Ca2+-Selective Channel To Be Published
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7X88
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![BU of 7x88 by Molmil](/molmil-images/mine/7x88) | |
3B98
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![BU of 3b98 by Molmil](/molmil-images/mine/3b98) | Crystal structure of zebrafish prostacyclin synthase (cytochrome P450 8A1) | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, Prostaglandin I2 synthase | Authors: | Li, Y.-C, Chiang, C.-W, Yeh, H.-C, Hsu, P.-Y, Whitby, F.G, Wang, L.-H, Chan, N.-L. | Deposit date: | 2007-11-03 | Release date: | 2007-11-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Structures of Prostacyclin Synthase and Its Complexes with Substrate Analog and Inhibitor Reveal a Ligand-specific Heme Conformation Change J.Biol.Chem., 283, 2008
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4NIC
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![BU of 4nic by Molmil](/molmil-images/mine/4nic) | |