7KPW

Structure of the H-lobe of yeast CKM

Summary for 7KPW

Entry DOI	10.2210/pdb7kpw/pdb
EMDB information	22990
Descriptor	Mediator of RNA polymerase II transcription subunit 12 (1 entity in total)
Functional Keywords	mediator, transcription, cdk8, med13, med12, cycc, cdk, argonaute, rna polymerase ii, piwi
Biological source	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Total number of polymer chains	1
Total formula weight	167049.81
Authors	Li, Y.C.,Chao, T.C.,Kim, H.J.,Cholko, T.,Chen, S.F.,Nakanishi, K.,Chang, C.E.,Murakami, K.,Garcia, B.A.,Boyer, T.G.,Tsai, K.L. (deposition date: 2020-11-12, release date: 2021-01-27, Last modification date: 2024-03-06)
Primary citation	Li, Y.C.,Chao, T.C.,Kim, H.J.,Cholko, T.,Chen, S.F.,Li, G.,Snyder, L.,Nakanishi, K.,Chang, C.E.,Murakami, K.,Garcia, B.A.,Boyer, T.G.,Tsai, K.L. Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module. Sci Adv, 7:-, 2021 Cited by PubMed: 33523904 DOI: 10.1126/sciadv.abd4484 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.9 Å)

Structure validation