7KPV

Structure of kinase and Central lobes of yeast CKM

Summary for 7KPV

Entry DOI	10.2210/pdb7kpv/pdb
EMDB information	22989
Descriptor	Meiotic mRNA stability protein kinase SSN3, RNA polymerase II holoenzyme cyclin-like subunit, Mediator of RNA polymerase II transcription subunit 12, ... (4 entities in total)
Functional Keywords	mediator, transcription, kinase, cdk8, med13, med12, cycc, cdk, argonaute, rna polymerase ii, piwi.
Biological source	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) More
Total number of polymer chains	4
Total formula weight	428000.47
Authors	Li, Y.C.,Chao, T.C.,Kim, H.J.,Cholko, T.,Chen, S.F.,Nakanishi, K.,Chang, C.E.,Murakami, K.,Garcia, B.A.,Boyer, T.G.,Tsai, K.L. (deposition date: 2020-11-12, release date: 2021-01-27, Last modification date: 2024-03-06)
Primary citation	Li, Y.C.,Chao, T.C.,Kim, H.J.,Cholko, T.,Chen, S.F.,Li, G.,Snyder, L.,Nakanishi, K.,Chang, C.E.,Murakami, K.,Garcia, B.A.,Boyer, T.G.,Tsai, K.L. Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module. Sci Adv, 7:-, 2021 Cited by PubMed: 33523904 DOI: 10.1126/sciadv.abd4484 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.8 Å)

Structure validation