7KPV

Structure of kinase and Central lobes of yeast CKM

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000122	biological_process	negative regulation of transcription by RNA polymerase II
A	0000166	molecular_function	nucleotide binding
A	0000307	cellular_component	cyclin-dependent protein kinase holoenzyme complex
A	0004672	molecular_function	protein kinase activity
A	0004674	molecular_function	protein serine/threonine kinase activity
A	0004693	molecular_function	cyclin-dependent protein serine/threonine kinase activity
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0006357	biological_process	regulation of transcription by RNA polymerase II
A	0006468	biological_process	protein phosphorylation
A	0008353	molecular_function	RNA polymerase II CTD heptapeptide repeat kinase activity
A	0009891	biological_process	positive regulation of biosynthetic process
A	0016301	molecular_function	kinase activity
A	0016592	cellular_component	mediator complex
A	0016740	molecular_function	transferase activity
A	0031648	biological_process	protein destabilization
A	0045944	biological_process	positive regulation of transcription by RNA polymerase II
A	0046872	molecular_function	metal ion binding
A	0051321	biological_process	meiotic cell cycle
A	0051726	biological_process	regulation of cell cycle
A	0060258	biological_process	negative regulation of filamentous growth
A	0070481	biological_process	nuclear-transcribed mRNA catabolic process, non-stop decay
A	0106310	molecular_function	protein serine kinase activity
A	1990508	cellular_component	CKM complex
B	0000122	biological_process	negative regulation of transcription by RNA polymerase II
B	0000411	biological_process	positive regulation of transcription by galactose
B	0000979	molecular_function	RNA polymerase II core promoter sequence-specific DNA binding
B	0005634	cellular_component	nucleus
B	0006357	biological_process	regulation of transcription by RNA polymerase II
B	0016538	molecular_function	cyclin-dependent protein serine/threonine kinase regulator activity
B	0016592	cellular_component	mediator complex
B	0034605	biological_process	cellular response to heat
B	0045944	biological_process	positive regulation of transcription by RNA polymerase II
B	0051321	biological_process	meiotic cell cycle
B	1990508	cellular_component	CKM complex
C	0000122	biological_process	negative regulation of transcription by RNA polymerase II
C	0000411	biological_process	positive regulation of transcription by galactose
C	0003712	molecular_function	transcription coregulator activity
C	0003713	molecular_function	transcription coactivator activity
C	0005634	cellular_component	nucleus
C	0006357	biological_process	regulation of transcription by RNA polymerase II
C	0016592	cellular_component	mediator complex
C	0045944	biological_process	positive regulation of transcription by RNA polymerase II
C	1990508	cellular_component	CKM complex
D	0000122	biological_process	negative regulation of transcription by RNA polymerase II
D	0003712	molecular_function	transcription coregulator activity
D	0003713	molecular_function	transcription coactivator activity
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0006357	biological_process	regulation of transcription by RNA polymerase II
D	0016592	cellular_component	mediator complex
D	0030332	molecular_function	cyclin binding
D	0045944	biological_process	positive regulation of transcription by RNA polymerase II
D	1990508	cellular_component	CKM complex

Functional Information from PROSITE/UniProt

site_id	PS00108
Number of Residues	13
Details	PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. VlHrDLKpaNIMV

Chain	Residue	Details
A	VAL282-VAL294

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10027","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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