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7KPV

Structure of kinase and Central lobes of yeast CKM

Functional Information from GO Data
ChainGOidnamespacecontents
A0000122biological_processnegative regulation of transcription by RNA polymerase II
A0000435biological_processpositive regulation of transcription from RNA polymerase II promoter by galactose
A0004672molecular_functionprotein kinase activity
A0004674molecular_functionprotein serine/threonine kinase activity
A0004693molecular_functioncyclin-dependent protein serine/threonine kinase activity
A0005524molecular_functionATP binding
A0005634cellular_componentnucleus
A0006355biological_processregulation of DNA-templated transcription
A0006468biological_processprotein phosphorylation
A0008353molecular_functionRNA polymerase II CTD heptapeptide repeat kinase activity
A0009891biological_processpositive regulation of biosynthetic process
A0016310biological_processphosphorylation
A0016592cellular_componentmediator complex
A0031648biological_processprotein destabilization
A0046872molecular_functionmetal ion binding
A0051321biological_processmeiotic cell cycle
A0051726biological_processregulation of cell cycle
A0060258biological_processnegative regulation of filamentous growth
A0070481biological_processnuclear-transcribed mRNA catabolic process, non-stop decay
A0106310molecular_functionprotein serine kinase activity
A1902554cellular_componentserine/threonine protein kinase complex
A1990508cellular_componentCKM complex
B0000122biological_processnegative regulation of transcription by RNA polymerase II
B0000411biological_processpositive regulation of transcription by galactose
B0000979molecular_functionRNA polymerase II core promoter sequence-specific DNA binding
B0005634cellular_componentnucleus
B0006357biological_processregulation of transcription by RNA polymerase II
B0016538molecular_functioncyclin-dependent protein serine/threonine kinase regulator activity
B0016592cellular_componentmediator complex
B0034605biological_processcellular response to heat
B0045944biological_processpositive regulation of transcription by RNA polymerase II
B0051321biological_processmeiotic cell cycle
B1990508cellular_componentCKM complex
C0000122biological_processnegative regulation of transcription by RNA polymerase II
C0000411biological_processpositive regulation of transcription by galactose
C0003712molecular_functiontranscription coregulator activity
C0003713molecular_functiontranscription coactivator activity
C0005634cellular_componentnucleus
C0006357biological_processregulation of transcription by RNA polymerase II
C0016592cellular_componentmediator complex
C0045944biological_processpositive regulation of transcription by RNA polymerase II
C1990508cellular_componentCKM complex
D0000122biological_processnegative regulation of transcription by RNA polymerase II
D0000435biological_processpositive regulation of transcription from RNA polymerase II promoter by galactose
D0003712molecular_functiontranscription coregulator activity
D0003713molecular_functiontranscription coactivator activity
D0005515molecular_functionprotein binding
D0005634cellular_componentnucleus
D0006357biological_processregulation of transcription by RNA polymerase II
D0016592cellular_componentmediator complex
D0030332molecular_functioncyclin binding
D0045944biological_processpositive regulation of transcription by RNA polymerase II
D1990508cellular_componentCKM complex
Functional Information from PROSITE/UniProt
site_idPS00108
Number of Residues13
DetailsPROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. VlHrDLKpaNIMV
ChainResidueDetails
AVAL282-VAL294

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:17330950
ChainResidueDetails
DSER370

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198
ChainResidueDetails
DSER375

site_idSWS_FT_FI3
Number of Residues3
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956
ChainResidueDetails
DSER425
DSER636
DSER748

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:19779198
ChainResidueDetails
DTHR601

site_idSWS_FT_FI5
Number of Residues1
DetailsMOD_RES: Phosphoserine; by PKA => ECO:0000269|PubMed:15225552, ECO:0007744|PubMed:19779198
ChainResidueDetails
DSER608

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PDB entries from 2024-10-16

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