3BW2
 
 | | Crystal structures and site-directed mutagenesis study of nitroalkane oxidase from Streptomyces ansochromogenes | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-nitropropane dioxygenase, FLAVIN MONONUCLEOTIDE | | Authors: | Li, Y.H, Gao, Z.Q, Hou, H.F. | | Deposit date: | 2008-01-08 | | Release date: | 2009-01-13 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure and site-directed mutagenesis of a nitroalkane oxidase from Streptomyces ansochromogenes
Biochem.Biophys.Res.Commun., 405, 2011
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1HQR
 | | CRYSTAL STRUCTURE OF A SUPERANTIGEN BOUND TO THE HIGH-AFFINITY, ZINC-DEPENDENT SITE ON MHC CLASS II | | Descriptor: | HLA-DR ALPHA CHAIN, HLA-DR BETA CHAIN, MYELIN BASIC PROTEIN, ... | | Authors: | Li, Y, Li, H, Dimasi, N, Schlievert, P, Mariuzza, R. | | Deposit date: | 2000-12-19 | | Release date: | 2001-01-03 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Crystal structure of a superantigen bound to the high-affinity, zinc-dependent site on MHC class II.
Immunity, 14, 2001
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4XVJ
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5YYF
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6IUS
 | | A higher kcat Rubisco | | Descriptor: | Ribulose-1,5-bisphosphate carboxylase/oxygenase | | Authors: | Li, Y, Cai, Z. | | Deposit date: | 2018-11-30 | | Release date: | 2019-12-04 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.12 Å) | | Cite: | A higher kcat Rubisco
To Be Published
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4N4H
 | | Crystal structure of the Bromo-PWWP of the mouse zinc finger MYND-type containing 11 isoform alpha in complex with histone H3.1K36me3 | | Descriptor: | DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, Peptide from Histone H3.1, ... | | Authors: | Li, Y, Ren, Y, Li, H. | | Deposit date: | 2013-10-08 | | Release date: | 2014-03-05 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.302 Å) | | Cite: | ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression
Nature, 508, 2014
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4N4G
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8GPX
 | | YFV_E_YD73Fab_postfusion | | Descriptor: | Envelope protein, YD73Fab_H, YD73Fab_K | | Authors: | Li, Y, Wu, L, Chai, Y, Qi, J, Yan, J, Gao, G.F. | | Deposit date: | 2022-08-27 | | Release date: | 2022-11-02 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | A neutralizing-protective supersite of human monoclonal antibodies for yellow fever virus.
Innovation (N Y), 3, 2022
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8GPU
 | | YFV_E_YD6Fab_prefusion | | Descriptor: | Envelope protein, YD6Fab_H, YD6Fab_L | | Authors: | Li, Y, Wu, L, Qi, J, Yan, J, Gao, G.F. | | Deposit date: | 2022-08-27 | | Release date: | 2022-11-02 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.79 Å) | | Cite: | A neutralizing-protective supersite of human monoclonal antibodies for yellow fever virus.
Innovation (N Y), 3, 2022
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6H8Q
 | | Structural basis for Scc3-dependent cohesin recruitment to chromatin | | Descriptor: | Cohesin subunit SCC3, DNA (5'-D(P*CP*TP*TP*TP*CP*GP*TP*TP*TP*CP*CP*TP*TP*GP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*CP*AP*AP*GP*GP*AP*AP*AP*CP*GP*AP*AP*AP*G)-3'), ... | | Authors: | Li, Y, Muir, K, Panne, D. | | Deposit date: | 2018-08-03 | | Release date: | 2018-08-29 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.631 Å) | | Cite: | Structural basis for Scc3-dependent cohesin recruitment to chromatin.
Elife, 7, 2018
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8EFM
 | | Structure of coral STING receptor from Stylophora pistillata in complex with 2',3'-cGAMP | | Descriptor: | SULFATE ION, Stimulator of interferon genes protein, cGAMP | | Authors: | Li, Y, Slavik, K.M, Morehouse, B.R, Mears, K, Kranzusch, P.J. | | Deposit date: | 2022-09-08 | | Release date: | 2023-07-05 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.13 Å) | | Cite: | cGLRs are a diverse family of pattern recognition receptors in innate immunity.
Cell, 186, 2023
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8GPT
 | | YFV_E_YD6scFv_postfusion | | Descriptor: | Envelope protein, YD6_VH, YD6_VL | | Authors: | Li, Y, Wu, L, Qi, J, Yan, J, Gao, G.F. | | Deposit date: | 2022-08-27 | | Release date: | 2022-11-02 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.07 Å) | | Cite: | A neutralizing-protective supersite of human monoclonal antibodies for yellow fever virus.
Innovation (N Y), 3, 2022
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8CX2
 | | Cryo-EM structure of human APOBEC3G/HIV-1 Vif/CBFbeta/ELOB/ELOC dimeric complex in State 2 | | Descriptor: | Core-binding factor subunit beta, DNA dC->dU-editing enzyme APOBEC-3G, Elongin-B, ... | | Authors: | Li, Y, Langley, C, Azumaya, C.M, Echeverria, I, Chesarino, N.M, Emerman, M, Cheng, Y, Gross, J.D. | | Deposit date: | 2022-05-19 | | Release date: | 2023-02-15 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | The structural basis for HIV-1 Vif antagonism of human APOBEC3G.
Nature, 615, 2023
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8CX0
 | | Cryo-EM structure of human APOBEC3G/HIV-1 Vif/CBFbeta/ELOB/ELOC monomeric complex | | Descriptor: | Core-binding factor subunit beta, DNA dC->dU-editing enzyme APOBEC-3G, Elongin-B, ... | | Authors: | Li, Y, Langley, C, Azumaya, C.M, Echeverria, I, Chesarino, N.M, Emerman, M, Cheng, Y, Gross, J.D. | | Deposit date: | 2022-05-19 | | Release date: | 2023-02-15 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | The structural basis for HIV-1 Vif antagonism of human APOBEC3G.
Nature, 615, 2023
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8CX1
 | | Cryo-EM structure of human APOBEC3G/HIV-1 Vif/CBFbeta/ELOB/ELOC dimeric complex in State 1 | | Descriptor: | Core-binding factor subunit beta, DNA dC->dU-editing enzyme APOBEC-3G, Elongin-B, ... | | Authors: | Li, Y, Langley, C, Azumaya, C.M, Echeverria, I, Chesarino, N.M, Emerman, M, Cheng, Y, Gross, J.D. | | Deposit date: | 2022-05-19 | | Release date: | 2023-02-15 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | The structural basis for HIV-1 Vif antagonism of human APOBEC3G.
Nature, 615, 2023
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8F2E
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5Y27
 | | Crystal structure of Se-Met Dpb4-Dpb3 | | Descriptor: | DNA polymerase epsilon subunit D, GLYCEROL, Putative transcription factor C16C4.22 | | Authors: | Li, Y, Gao, F, Su, M, Zhang, F.B, Chen, Y.H. | | Deposit date: | 2017-07-24 | | Release date: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Coordinated regulation of heterochromatin inheritance by Dpb3-Dpb4 complex.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5C2O
 | | Crystal structure of Streptococcus mutans Deoxycytidylate Deaminase complexed with dTTP | | Descriptor: | MAGNESIUM ION, Putative deoxycytidylate deaminase, THYMIDINE-5'-TRIPHOSPHATE, ... | | Authors: | Li, Y.H, Gao, Z.Q, Hou, H.F, Dong, Y.H. | | Deposit date: | 2015-06-16 | | Release date: | 2016-07-13 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Mechanism of the allosteric regulation of Streptococcus mutans 2'-deoxycytidylate deaminase.
Acta Crystallogr D Struct Biol, 72, 2016
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8WNS
 | | Cryo EM map of SLC7A10 in the apo state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Amino acid transporter heavy chain SLC3A2, Asc-type amino acid transporter 1 | | Authors: | Li, Y.N, Guo, Y.Y, Dai, L, Yan, R.H. | | Deposit date: | 2023-10-06 | | Release date: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.42 Å) | | Cite: | Cryo-EM structure of the human Asc-1 transporter complex.
Nat Commun, 15, 2024
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8WNY
 | | Cryo EM map of SLC7A10-SLC3A2 complex in the D-serine bound state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Amino acid transporter heavy chain SLC3A2, Asc-type amino acid transporter 1, ... | | Authors: | Li, Y.N, Guo, Y.Y, Dai, L, Yan, R.H. | | Deposit date: | 2023-10-06 | | Release date: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Cryo-EM structure of the human Asc-1 transporter complex.
Nat Commun, 15, 2024
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8WNT
 | | Cryo EM map of SLC7A10 with L-Alanine substrate | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ALANINE, ... | | Authors: | Li, Y.N, Guo, Y.Y, Dai, L, Yan, R.H. | | Deposit date: | 2023-10-06 | | Release date: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.42 Å) | | Cite: | Cryo-EM structure of the human Asc-1 transporter complex.
Nat Commun, 15, 2024
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8XAB
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8JA5
 | | Crystal structure of Nipah Virus attachment (G) glycoprotein in complex with neutralizing antibody 14F8 | | Descriptor: | 14F8 antibody heavy chain, 14F8 antibody light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Li, Y.H, Huang, X.Y, Xu, J.J, Chen, W. | | Deposit date: | 2023-05-05 | | Release date: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.79 Å) | | Cite: | Crystal structure of Nipah Virus attachment (G) glycoprotein in complex with neutralizing antibody 14F8
To Be Published
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6U18
 | | Directed evolution of a biosensor selective for the macrolide antibiotic clarithromycin | | Descriptor: | CITRATE ANION, CLARITHROMYCIN, Erythromycin resistance repressor protein | | Authors: | Li, Y, Reed, M, Wright, H.T, Cropp, T.A, Williams, G. | | Deposit date: | 2019-08-15 | | Release date: | 2020-08-19 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Development of Genetically Encoded Biosensors for Reporting the Methyltransferase-Dependent Biosynthesis of Semisynthetic Macrolide Antibiotics.
Acs Synth Biol, 2021
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8GZ1
 | | Cryo-EM structure of human NaV1.6/beta1/beta2,apo state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, Sodium channel protein type 8 subunit alpha, ... | | Authors: | Li, Y, Jiang, D. | | Deposit date: | 2022-09-24 | | Release date: | 2023-03-08 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure of human Na V 1.6 channel reveals Na + selectivity and pore blockade by 4,9-anhydro-tetrodotoxin.
Nat Commun, 14, 2023
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