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PDB: 21237 件

7T4R
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BU of 7t4r by Molmil
CryoEM structure of the HCMV Pentamer gH/gL/UL128/UL130/UL131A in complex with THBD and neutralizing fabs MSL-109 and 13H11
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, Envelope glycoprotein L, ...
著者Kschonsak, M, Johnson, M.C, Schelling, R, Green, E.M, Rouge, L, Ho, H, Patel, N, Kilic, C, Kraft, E, Arthur, C.P, Rohou, A.L, Comps-Agrar, L, Martinez-Martin, N, Perez, L, Payandeh, J, Ciferri, C.
登録日2021-12-10
公開日2022-03-23
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for HCMV Pentamer receptor recognition and antibody neutralization.
Sci Adv, 8, 2022
5JKG
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BU of 5jkg by Molmil
The crystal structure of FGFR4 kinase domain in complex with LY2874455
分子名称: 2-[4-[E-2-[5-[(1R)-1-[3,5-bis(chloranyl)pyridin-4-yl]ethoxy]-1H-indazol-3-yl]ethenyl]pyrazol-1-yl]ethanol, Fibroblast growth factor receptor 4
著者Wu, D, Chen, L, Chen, Y.
登録日2016-04-26
公開日2016-10-05
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.352 Å)
主引用文献Crystal Structure of the FGFR4/LY2874455 Complex Reveals Insights into the Pan-FGFR Selectivity of LY2874455
Plos One, 11, 2016
6H6N
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BU of 6h6n by Molmil
UbiJ-SCP2 Ubiquinone synthesis protein
分子名称: CALCIUM ION, TERBIUM(III) ION, Ubiquinone biosynthesis protein UbiJ
著者Fyfe, C.D, Legrand, P, Pecqueur, L, Ciccone, L, Lombard, M, Fontecave, M.
登録日2018-07-28
公開日2019-02-13
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献A Soluble Metabolon Synthesizes the Isoprenoid Lipid Ubiquinone.
Cell Chem Biol, 26, 2019
7BVH
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BU of 7bvh by Molmil
Crystal structure of arabinosyltransferase EmbC2-AcpM2 complex from Mycobacterium smegmatis complexed with di-arabinose
分子名称: CALCIUM ION, Integral membrane indolylacetylinositol arabinosyltransferase EmbC, Meromycolate extension acyl carrier protein, ...
著者Zhao, Y, Zhang, L, Wu, L.J, Wang, Q, Li, J, Besra, G.S, Rao, Z.H.
登録日2020-04-10
公開日2020-04-29
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol.
Science, 368, 2020
6H6P
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BU of 6h6p by Molmil
UbiJ-SCP2 Ubiquinone synthesis protein
分子名称: CALCIUM ION, PENTAETHYLENE GLYCOL, Ubiquinone biosynthesis protein UbiJ
著者Fyfe, C.D, Legrand, P, Pecqueur, L, Ciccone, L, Lombard, M, Fontecave, M.
登録日2018-07-28
公開日2019-02-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A Soluble Metabolon Synthesizes the Isoprenoid Lipid Ubiquinone.
Cell Chem Biol, 26, 2019
3B9L
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BU of 3b9l by Molmil
Human serum albumin complexed with myristate and AZT
分子名称: 3'-azido-3'-deoxythymidine, MYRISTIC ACID, Serum albumin
著者Zhu, L, Yang, F, Chen, L, Meehan, E.J, Huang, M.
登録日2007-11-05
公開日2008-05-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A new drug binding subsite on human serum albumin and drug-drug interaction studied by X-ray crystallography
J.Struct.Biol., 162, 2008
6LKC
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BU of 6lkc by Molmil
Crystal structure of PfaD from Shewanella piezotolerans in complex with FMN
分子名称: CALCIUM ION, FLAVIN MONONUCLEOTIDE, GLYCEROL, ...
著者Zhang, M.L, Li, Q, Meng, S.S, Guo, L.J, He, L, Huang, J.Z, Li, L, Zhang, H.D.
登録日2019-12-19
公開日2020-12-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.998 Å)
主引用文献Structural Insights into the Trans -Acting Enoyl Reductase in the Biosynthesis of Long-Chain Polyunsaturated Fatty Acids in Shewanella piezotolerans .
J.Agric.Food Chem., 69, 2021
7BVF
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BU of 7bvf by Molmil
Cryo-EM structure of Mycobacterium tuberculosis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with ethambutol
分子名称: CALCIUM ION, CARDIOLIPIN, Ethambutol, ...
著者Zhang, L, Zhao, Y, Gao, Y, Wang, Q, Li, J, Besra, G.S, Rao, Z.
登録日2020-04-10
公開日2020-04-29
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol.
Science, 368, 2020
7BVC
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BU of 7bvc by Molmil
Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with ethambutol
分子名称: 4'-PHOSPHOPANTETHEINE, CALCIUM ION, CARDIOLIPIN, ...
著者Zhang, L, Zhao, Y, Gao, Y, Wang, Q, Li, J, Besra, G.S, Rao, Z.
登録日2020-04-10
公開日2020-04-29
最終更新日2020-07-01
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol.
Science, 368, 2020
7BVE
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BU of 7bve by Molmil
Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbC2-AcpM2 in complex with ethambutol
分子名称: CALCIUM ION, Ethambutol, Integral membrane indolylacetylinositol arabinosyltransferase EmbC, ...
著者Zhang, L, Zhao, Y, Gao, Y, Wang, Q, Li, J, Besra, G.S, Rao, Z.
登録日2020-04-10
公開日2020-04-29
最終更新日2020-07-01
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol.
Science, 368, 2020
8CEA
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BU of 8cea by Molmil
Cytochrome c maturation complex CcmABCD, E154Q
分子名称: Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, Heme exporter protein C, ...
著者Ilcu, L, Zhang, L, Einsle, O.
登録日2023-02-01
公開日2023-09-06
実験手法ELECTRON MICROSCOPY (3.94 Å)
主引用文献Architecture of the Heme-translocating CcmABCD/E complex required for Cytochrome c maturation.
Nat Commun, 14, 2023
8CE1
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BU of 8ce1 by Molmil
Cytochrome c maturation complex CcmABCD
分子名称: Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, Heme exporter protein C, ...
著者Ilcu, L, Zhang, L, Einsle, O.
登録日2023-02-01
公開日2023-09-06
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Architecture of the Heme-translocating CcmABCD/E complex required for Cytochrome c maturation.
Nat Commun, 14, 2023
4NOM
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BU of 4nom by Molmil
Crystal structure of asparaginyl endopeptidase (AEP)/Legumain activated at pH 4.5
分子名称: Legumain
著者Zhao, L, Hua, T, Ru, H, Ni, X, Shaw, N, Jiao, L, Ding, W, Qu, L, Ouyang, S, Liu, Z.J.
登録日2013-11-19
公開日2014-02-19
最終更新日2014-03-19
実験手法X-RAY DIFFRACTION (2.006 Å)
主引用文献Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage.
Cell Res., 24, 2014
7BVG
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BU of 7bvg by Molmil
Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with di-arabinose.
分子名称: 4'-PHOSPHOPANTETHEINE, CALCIUM ION, CARDIOLIPIN, ...
著者Zhang, L, Zhao, Y, Gao, Y, Wang, Q, Li, J, Besra, G.S, Rao, Z.
登録日2020-04-10
公開日2020-04-29
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol.
Science, 368, 2020
4NOK
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BU of 4nok by Molmil
Crystal structure of proenzyme asparaginyl endopeptidase (AEP)/Legumain at pH 7.5
分子名称: Legumain
著者Zhao, L, Hua, T, Ru, H, Ni, X, Shaw, N, Jiao, L, Ding, W, Qu, L, Ouyang, S, Liu, Z.J.
登録日2013-11-19
公開日2014-02-19
最終更新日2014-03-19
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage.
Cell Res., 24, 2014
5NP5
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BU of 5np5 by Molmil
Abl2 SH3 pTyr116/161
分子名称: Abelson tyrosine-protein kinase 2, SULFATE ION
著者Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L.
登録日2017-04-13
公開日2018-05-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions.
J.Biol.Chem., 294, 2019
8P7G
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BU of 8p7g by Molmil
Structural characterization of PHOX2B and its DNA interactions shed lights into the molecular basis of the + 7Ala variant pathogenicity in CCHS
分子名称: Paired mesoderm homeobox protein 2B
著者Russo, L, Diana, D, Fattorusso, R.
登録日2023-05-30
公開日2024-05-15
最終更新日2024-06-26
実験手法SOLUTION NMR
主引用文献Structural characterization of PHOX2B and its DNA interaction shed light on the molecular basis of the +7Ala variant pathogenicity in CCHS.
Chem Sci, 15, 2024
6LR0
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BU of 6lr0 by Molmil
structure of human bile salt exporter ABCB11
分子名称: Bile salt export pump
著者Wang, L, Hou, W.T, Chen, L, Jiang, Y.L, Xu, D, Sun, L.F, Zhou, C.Z, Chen, Y.
登録日2020-01-15
公開日2020-04-15
最終更新日2023-01-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structure of human bile salts exporter ABCB11.
Cell Res., 30, 2020
6OSO
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BU of 6oso by Molmil
The crystal structure of the isolate tryptophan synthase alpha-chain from Salmonella enterica serovar typhimurium at 1.75 Angstrom resolution
分子名称: CHLORIDE ION, DIMETHYL SULFOXIDE, SULFATE ION, ...
著者Hilario, E, Dunn, M.F, Mueller, L, Chang, C, Fan, L.
登録日2019-05-01
公開日2020-05-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Backbone assignments and conformational dynamics in the S. typhimurium tryptophan synthase alpha-subunit from solution-state NMR.
J.Biomol.Nmr, 74, 2020
3B9M
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BU of 3b9m by Molmil
Human serum albumin complexed with myristate, 3'-azido-3'-deoxythymidine (AZT) and salicylic acid
分子名称: 2-HYDROXYBENZOIC ACID, 3'-azido-3'-deoxythymidine, MYRISTIC ACID, ...
著者Zhu, L, Yang, F, Chen, L, Meehan, E.J, Huang, M.
登録日2007-11-05
公開日2008-05-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A new drug binding subsite on human serum albumin and drug-drug interaction studied by X-ray crystallography
J.Struct.Biol., 162, 2008
6OUY
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BU of 6ouy by Molmil
The crystal structure of the isolate tryptophan synthase alpha-chain from Salmonella enterica serovar typhimurium at 1.60 Angstrom resolution
分子名称: CHLORIDE ION, DIMETHYL SULFOXIDE, SULFATE ION, ...
著者Hilario, E, Dunn, M.F, Mueller, L, Chang, C, Fan, L.
登録日2019-05-06
公開日2020-05-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Backbone assignments and conformational dynamics in the S. typhimurium tryptophan synthase alpha-subunit from solution-state NMR.
J.Biomol.Nmr, 74, 2020
6XEY
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BU of 6xey by Molmil
Cryo-EM structure of the SARS-CoV-2 spike glycoprotein bound to Fab 2-4
分子名称: 2-4 Heavy Chain, 2-4 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Rapp, M, Shapiro, L, Ho, D.D.
登録日2020-06-14
公開日2020-07-22
最終更新日2021-01-27
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike.
Nature, 584, 2020
8OSL
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BU of 8osl by Molmil
Cryo-EM structure of CLOCK-BMAL1 bound to the native Por enhancer nucleosome (map 2, additional 3D classification and flexible refinement)
分子名称: Basic helix-loop-helix ARNT-like protein 1, Circadian locomoter output cycles protein kaput, DNA (147-MER), ...
著者Michael, A.K, Stoos, L, Kempf, G, Cavadini, S, Thoma, N.
登録日2023-04-19
公開日2023-05-24
最終更新日2023-07-26
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Cooperation between bHLH transcription factors and histones for DNA access.
Nature, 619, 2023
8OTS
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BU of 8ots by Molmil
OCT4 and MYC-MAX co-bound to a nucleosome
分子名称: DNA (127-MER), Green fluorescent protein,POU domain, class 5, ...
著者Michael, A.K, Stoos, L, Kempf, G, Cavadini, S, Thoma, N.
登録日2023-04-21
公開日2023-05-24
最終更新日2023-07-26
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cooperation between bHLH transcription factors and histones for DNA access.
Nature, 619, 2023
8OSK
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BU of 8osk by Molmil
Cryo-EM structure of CLOCK-BMAL1 bound to a nucleosomal E-box at position SHL+5.8 (composite map)
分子名称: Basic helix-loop-helix ARNT-like protein 1, Circadian locomoter output cycles protein kaput, DNA (124-MER), ...
著者Stoos, L, Michael, A.K, Kempf, G, Cavadini, S, Thoma, N.H.
登録日2023-04-19
公開日2023-05-24
最終更新日2023-07-26
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cooperation between bHLH transcription factors and histones for DNA access.
Nature, 619, 2023

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