4NOM
Crystal structure of asparaginyl endopeptidase (AEP)/Legumain activated at pH 4.5
Summary for 4NOM
Entry DOI | 10.2210/pdb4nom/pdb |
Related | 4NOJ 4NOK 4NOL |
Descriptor | Legumain (2 entities in total) |
Functional Keywords | new fold, asparaginyl endopeptidase, substrate, extracellular, hydrolase |
Biological source | Mus musculus (mouse) |
Cellular location | Lysosome: O89017 |
Total number of polymer chains | 1 |
Total formula weight | 50266.76 |
Authors | |
Primary citation | Zhao, L.,Hua, T.,Crowley, C.,Ru, H.,Ni, X.,Shaw, N.,Jiao, L.,Ding, W.,Qu, L.,Hung, L.W.,Huang, W.,Liu, L.,Ye, K.,Ouyang, S.,Cheng, G.,Liu, Z.J. Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage. Cell Res., 24:344-358, 2014 Cited by PubMed: 24407422DOI: 10.1038/cr.2014.4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.006 Å) |
Structure validation
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